Clinical trials: Reduce the Incidence of or Contamination/Infection Transmission;
CGA
Preoperative Comprehensive Geriatric Assessment (CGA) and Postoperative Delirium
The purpose of this research is to find out the best way to reduce delirium in frail, older patients undergoing planned surgery. Delirium is a state of confusion and difficulty concentrating that is temporary.
- Trial name
- NCT07059585
- Testing
- CGA, control
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Tracheal Intubation
Triamcinolone Paste to Reduce the Incidence of Postoperative Sore Throat
The purpose of this study is to determine whether triamcinolone paste applied over tracheal tube is effective to reduce the incidence of postoperative sore throat after tracheal intubation.
- Trial name
- NCT00908817
- Testing
- triamcinolone acetonide, chlorhexidine gluconate
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Soonchunhyang University Hospital
Pregnancy
Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects
The purpose of this study is to determine what dose of medication administered through a combined spinal epidural (CSE) provides the optimal pain relief with the minimal amount of side effects.
- Trial name
- NCT02159807
- Testing
- Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Kidney Failure
RUCONEST® as a Therapeutic Strategy to Reduce the Incidence of Delayed Graft Function
An unmet medical need exists for therapeutic regimens in transplantation that allow immediate postoperative graft function, thereby improving graft survival.
- Trial name
- NCT03791476
- Testing
- rhC1INH, Saline Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Transmission, Other/Miscellaneous
Slippers to Reduce Transfer From Floors to Surfaces
The goal of this study is to determine if wearing slippers will reduce transfer of bacteriophage MS2 from hospital room floors to surfaces in the room and hands of patients.
- Trial name
- NCT04935892
- Testing
- Slippers
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Louis Stokes VA Medical Center
Surgical Wound Infection
Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection
The purpose of this study is to determine if the use of supplemental oxygen at 80% FIO2 can reduce the incidence of surgical site infection after emergency cesarean section.
- Trial name
- NCT01340534
- Testing
- Supplemental oxygen 80% FIO2, Use of air (no oxygen during surgery)
- Where
- Panama
- Volunteers
- 370 people
- Sponsor
- Saint Thomas Hospital, Panama
Urinary Tract Infections, Kidney Transplant; Complications
Double Voiding and Post-transplant UTI
Urinary tract infections (UTI) are common in kidney transplant recipients and are an important cause of illness and hospital admissions.
- Trial name
- NCT05711446
- Testing
- Double Voiding, Regular Voiding
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Weill Medical College of Cornell University
Stroke, Cerebrovascular Accident
Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke
Armodafinil is an FDA approved medication with wakefulness-promoting properties. It is a relatively safe agent with interesting neurochemical effects on the catecholamine system, producing an improvement in cognitive function…
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT01896128
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Burke Rehabilitation Hospital
Suicidal Ideation, Suicide Attempts
A Feasibility Study of a Suicide Prevention Video
This initial study is a pilot feasibility study with a primary objective of assessing the feasibility of a larger study by evaluating the procedures and methodology, as well as collecting pilot data.
- Conditions
- Suicidal Ideation, Suicide Attempts, Psychiatric Illness
- Trial name
- NCT05119946
- Testing
- Suicide prevention video, Standard suicide treatment
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Fraser Health
Acute Graft Versus Host Disease, Malignant Hematologic Neoplasm
Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases
Evaluating the safety and effectiveness of a CD25 monoclonal antibody-based prophylactic acute graft-versus-host-disease (aGVHD) regimen following unrelated umbilical cord blood transplantation (UCBT) for malignant hematologic…
- Trial name
- NCT06480630
- Testing
- Basiliximab
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Anhui Provincial Hospital
Bacterial Contamination Rate of the Cell Phones
Surveillance Study of Bacterial Contamination of the Parent's Cell Phone in the NICU
The purpose of this study is to determine the contamination rate of the parents cell phone in a newborn intensive care setting and identify the types of bacteria contaminating the cell phone as well as evaluating the…
- Trial name
- NCT01560936
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Hypotension, Hemodynamic Instability
The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery
The "Hypotension Prediction Index (HPI)" was established by the Edwards Lifescience Company (Irvine, California, USA) and is CE certified.
- Conditions
- Hypotension, Hemodynamic Instability, Renal Failure, Myocardial Injury
- Trial name
- NCT04149314
- Testing
- HPI based hemodynamic optimization algorithm
- Where
- Germany
- Volunteers
- 142 people
- Sponsor
- University of Giessen
Bladder Cancer
Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery
The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to reducing the incidence of surgical site infections and incidence of unnecessary prescribing of antibiotics.
- Trial name
- MACS (NCT05392634)
- Testing
- Meropenem 1000 mg, Amoxicillin+clavulanic acid 1200 mg or Cefuroksim 1500mg
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Incidence of cs Scar Infection
Normal Saline Versus Betadine Use to Reduce the Incidence of Wound Infection in Cesarean Section
This is a prospective randomized controlled study to the difference between using normal saline or betadine irrigation of wound prior to skin closure in reducing the incidence of wound infection after Cesarean section.
- Trial name
- NCT03725748
- Testing
- irrigation
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Cardiac Disease, Multiple Organ Dysfunction Syndrome
Hemoperfusion Efferon LPS During Cardiac Surgery Using Cardiopulmonary Bypass
More than 1 million people undergo cardiac surgery each year worldwide. Cardiac surgeries still in most cases require cardiopulmonary bypass, use of myocardial protection against aortic clamping and creation of cardioplegic…
- Trial name
- NCT06659289
- Testing
- Efferon LPS
- Where
- Russia
- Volunteers
- 14 people
- Sponsor
- Efferon JSC
Adult Patients Undergoing CABG
Effect of Preoperative Stellate Ganglion Block on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting
The primary objective of this study is to determine the feasibility of preoperative stellate ganglion block in reducing the incidence of postoperative atrial fibrillation in patients undergoing CABG.
- Trial name
- NCT07271615
- Testing
- Stellate Ganglion Block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Virus Diseases, Hepatitis B
Pilot Safety Study to Determine the Ability of the Protector Cap Jet Injector to Prevent Cross-Contamination
The primary purpose of this study is to determine the ability of the Protector Cap Jet Injector to prevent cross-contamination in the next injection sample.
- Trial name
- NCT00219453
- Testing
- Jet Injector with Protector Cap (HSI-500)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- PATH
Periprocedural Myocardial Necrosis
Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs)
An increase in cardiac biomarkers has been shown to occur in 5% to 30% of patients after otherwise successful percutaneous coronary interventions (PCIs)(1) Apart from side-branch occlusion, intimal dissection and coronary spasm…
- Trial name
- ROMA (NCT01007279)
- Testing
- ROSUVASTATIN
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Roma La Sapienza
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation
Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce the severity of oral mucositis (OM) in adult patients with squamous cell…
- Conditions
- Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
- Trial name
- NCT03972527
- Testing
- Photobiomodulation, Routine Oral Care and Analgesia
- Where
- 12 sites in United States
- Volunteers
- 85 people
- Sponsor
- MuReva Phototherapy Inc.
Thyroid Surgery, Inadvertent Parathyroidectomy
Use of the PTEye Device to Reduce Inadvertent Parathyroidectomy During Thyroid Surgery
Inadvertent Parathyroidectomy (IP) during thyroid surgery may lead to transient or permanent hypoparathyroidism and hypocalcemia, which represents significant morbidity.
- Conditions
- Thyroid Surgery, Inadvertent Parathyroidectomy, Enlarged Thyroid
- Trial name
- NCT06927245
- Testing
- PTeye Device
- Volunteers
- 25 people
- Sponsor
- ProMedica Health System