Clinical trials: Reduced Ejection Fraction
Heart Failure With Reduced Ejection Fraction HFrEF
Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction
Guidelines-directed medical therapy has improved dramatically outcomes in heart failure with reduced ejection fraction (HFrEF) patients.
- Trial name
- NCT05179070
- Testing
- Carvedilol
- Where
- Indonesia
- Volunteers
- 26 people
- Sponsor
- Universitas Sebelas Maret
Heart Failure
REDUCE LAP-HFREF TRIAL
The objective of this pilot study is to evaluate the safety and performance of implanting the IASD® System II in Heart Failure patients with reduced ejection fraction and elevated left sided filling pressures, who remain…
- Trial name
- NCT03093961
- Testing
- IASD implant
- Where
- 4 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Corvia Medical
Heart Failure, Heart Failure With Reduced Ejection Fraction
TRAnscutaneous vaGUS Nerve Stimulation in Patients With Chronic Heart Failure
To verify the efficacy of transcutaneous vagus nerve stimulation (tVNS) on and autonomic balance in patients with chronic heart failure and reduced (HFrEF) or mildly reduced (HFmrEF) left ventricular ejection fraction.
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Midrange Ejection Fraction
- Trial name
- TRAGUS-HF (NCT06355388)
- Testing
- Active tVNS
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
Heart Failure
Heart Failure Ventricular Pressure Time Profile
This proposed study aim to: 1. Determine intra-LV pressure-time profile non-invasively using recently developed echo Doppler VFM analysis and applanation tonometry and myocardial elastic properties, in HF subjects (both HFNEF and…
- Trial name
- HF-VFM (NCT02791074)
- Testing
- NTproBNP, Echocardiography, Arterial tonometry
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Heart Failure, Reduced Ejection Fraction
Cardiometabolic Effects of Dapagliflozin in Heart Failure With Reduced or Mildly Reduced Ejection Fraction
Gliflozins have demonstrated a beneficial effect in terms of incident heart failure and related events in patients with or without diabetes.
- Trial name
- ICARD (NCT05420285)
- Testing
- Dapagliflozin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure, Systolic
TRANSFORM Heart Failure with Reduced Ejection Fraction
The goal of the TRANSFORM-HFrEF trial will be to study the current guideline-directed medical therapy (GDMT) landscape for HFrEF and determine effective methods and models of increasing adherence to GDMT and improving Quality of…
- Trial name
- TRANSFORMHFrEF (NCT04872959)
- Testing
- HealthReveal
- Sponsor
- Massachusetts General Hospital