Clinical trials: Reduction in Pain
Bacterial Load Reduction, Postoperative Pain
Evaluation of Postoperative Pain and Bacterial Load After Hyalone or Calcium Hydroxide Medication in Mandibular First Molars
This randomized controlled clinical trial aims to evaluate the effect of Hyalone hydrogel compared with calcium hydroxide as an intracanal medicament on postoperative pain and bacterial load reduction in mandibular first molars…
- Trial name
- HYACAL-ENDO (NCT07775456)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pain During Outpatient Hysteroscopy, Pain Reduction in Outpatient Hysteroscopy
Warm Versus Room Temperature Saline as a Uterine Distension Medium for Pain Reduction in Women Undergoing Outpatient Hysteroscopy: Protocol for a Randomized Controlled Trial
The goal of this randomized clinical trial is to determine whether using warmed saline at 37°C during outpatient diagnostic hysteroscopy can reduce pain compared with room-temperature saline.
- Trial name
- NCT07773376
- Testing
- Warmed Saline at 37 degrees celsius, Room-Temperature Normal Saline
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Reem Mohamed
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Pain Score Reduction, Cesarian Section
Stratafix vs. PDS (Fascial Closure RCT)
This proposed prospective, randomized, single-blinded controlled trial will directly compare Stratafix anti-microbial barbed sutures and standard PDS sutures for fascial closure at the time of Cesarean delivery.
- Trial name
- NCT07574086
- Testing
- Polydioxanone Plus, Polydioxanone (PDS)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arizona
We Are Not Studying a Disease or Condition, Pain Reduction
Effect of Diode Laser and 20% Benzocaine Anesthetic Gel on Pain Reduction Following Tooth Separation With Elastomeric Separators in Fixed Orthodontic Patients: A Randomized Trial in Karachi-Pakistan
The goal of this clinical trial is to learn if low level laser therapy works equivalent to benzocaine in reducing the pain caused by separators in fixed orthodontic treatment.
- Trial name
- NCT07558720
- Testing
- Laser, Benzocaine 20%
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Postoperative Pain Control, Breast Reduction
Surgeon-Guided Serratus Block in Breast Reduction Surgery
Surgeon guided serratus block, which can be performed by the surgeon in participants undergoing breast reduction surgery, may reduce the sensation of pain from the surgical field in the postoperative period.
- Trial name
- NCT06905574
- Testing
- surgeon guided serratus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- alperen can kokten
Bacterial Count Reduction in Oval Canal After Rotary Instrumentation With Different Systems, Post-operative Pain After Rotary Instrumentation of Oval Canal With Different Systems
Postoperative Pain and Bacterial Reduction in Oval Canals After Instrumentation With Different Noval Rotary Files Systems
Postoperative pain after endodontic treatment can affect a patient's quality of life. It is reported that debris extrusion after the instrumentation technique can influence postoperative pain.
- Trial name
- NCT07019792
- Testing
- Protaper ultimate, Truanatomy file system, Hyflex EDM
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Opioid Analgesia, Pain, Postoperative
The Effect of Tap Block in Pain Relief in Pediatric Patients
TAP block applied for analgesic purposes in pediatric patients undergoing appendectomy surgery provides superior analgesia in analgesic relief in the first 24 hours postoperatively compared to the placebo-control group without…
- Conditions
- Opioid Analgesia, Pain, Postoperative, Pain Score Reduction
- Trial name
- NCT06812169
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arnavutkoy State Hospital
Anesthesia, Acute Pain
Comparative Effects of Ciprofol and Propofol on Pain Intensity on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study
Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in…
- Conditions
- Anesthesia, Acute Pain, Risk Reduction
- Trial name
- NCT06020469
- Where
- China
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Guangdong Second Provincial General Hospital
Anesthesia, Acute Pain
Construction of Perioperative Medical Data Platform and Its Typical Practice to Predict Postoperative Acute Moderate to Severe Pain With Machine Learning Models
Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in…
- Conditions
- Anesthesia, Acute Pain, Risk Reduction
- Trial name
- NCT05569460
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Guangdong Second Provincial General Hospital
Acute Coronary Syndrome, Chest Pain
Standardizing Emergency Work-ups Around Risk Data
Chest pain is the second leading reason for emergency department (ED) visits in the United States. Resource utilization for this ED subpopulation is particularly high, in part due to a dearth of accepted standardized clinical…
- Conditions
- Acute Coronary Syndrome, Chest Pain, Risk Reduction
- Trial name
- STEWARD (NCT03286179)
- Testing
- modified HEART score and/or Emergency Department Assessment of Chest pain Risk Score (EDACS)
- Where
- 12 sites in United States
- Volunteers
- 13,419 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Reduction in Post Ceasarean-section Related Pain in Study Group (TAP Block)
Post Caesarean-Section Pain Control Regimens: Oral Regimen With and Without Transversus Abdominis Plane Block
Patients at Mbarara Regional Referral Hospital (MRRH) in Uganda who present for routine caesarean sections often go without a set post-operative pain control regimen.
- Trial name
- NCT01982929
- Testing
- TAP block (Bupivacaine 0.25% with epinephrine)
- Where
- Uganda
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vicki Modest, MD
Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis
Effect of Occlusal Reduction on Post-operative Pain
effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis
- Conditions
- Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis, Apical Periodontitis
- Trial name
- NCT03189771
- Testing
- occlusal surface reduction
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Haemostatic, Bacterial De-contamination
Pilot Study,Diode Laser 808 nm Supported Direct Pulp Capping in Permanent Teeth
The purpose of this study was to compare the conventional and diode 808 nm laser-assisted techniques in direct pulp capping in permanent teeth .The present study was based on a series of ten clinical studies with pulp exposure…
- Conditions
- Haemostatic, Bacterial De-contamination, Bio-stimulation, Reparative Dentine Formation
- Trial name
- Laser in DPC (NCT01907919)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yazdanfar, Iraj, M.D.
Pain Reduction, Function Improvement
Duloxetine for Pain in Older Adults With Knee Osteoarthritis (OA)
Osteoarthritis (OA), a common disabling condition, is the commonest type of arthritis worldwide.Pain is the leading symptom and is often chronic in na.
- Trial name
- NCT01425827
- Testing
- duloxetine HCL
- Where
- Egypt
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- University of Alexandria