Clinical trials: Reduction of Cardiovascular Risk Factors
Obesity
Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss
The purpose of the trial was to examine the independent effects of equivalent diet- or exercise-induced weight loss on obesity and related cardiovascular health risk factors.
- Trial name
- NCT00664547
- Testing
- Diet Weight Loss, Exercise Weight Loss, Exercise Without Weight Loss
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Cardiovascular Disease, Dietary Modification
Effects of Reduction in Saturated Fat on Cholesterol and Lipoproteins in Lean and Obese Persons
A randomized controlled clinical trial comparing the effect of substitution of unsaturated fat from nuts and oils for saturated fat from meat and dairy foods on serum lipids in normal weight and obese subjects with elevated LDL…
- Conditions
- Cardiovascular Disease, Dietary Modification, Cardiovascular Risk Factors
- Trial name
- NCT02589769
- Testing
- unsaturated fat for saturated fat, saturated fat
- Where
- Norway
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiovascular Diseases, Metabolic Syndrome
Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention
The purpose of this study is to evaluate the feasibility of a 6-month family-based community intervention to mitigate cardiovascular disease risk factors in Hispanic families in northern Colorado as measured through biometric…
- Trial name
- NCT05322876
- Testing
- Healthy Hearts Family Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System
Diabetes Mellitus, Hypertension
Efficacy of Exercise at a Fitness Club for Cardiovascular Risk Reduction
The purpose of the study is to determine whether exercise has further beneficial effects on improving cardiovascular risk factors such as hypertension, high cholesterol level or diabetes mellitus, when added to the standard…
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- NCT00106236
- Testing
- exercise
- Where
- Japan
- Volunteers
- 561 people
- Sponsor
- Sapporo Health Promotion Foundation
Heart Diseases, Hiv
Whole Food Plant-Based Diet for HIV-Associated Reduction in Cardiovascular Risk (PLANT-HART)
The goal of this clinical trial is to evaluate the impact of using a whole food plant-based diet in the reduction of cardiovascular risk related to HIV in people who live with HIV infection.
- Trial name
- PLANT-HART (NCT05796882)
- Testing
- Whole Food Plant-Based Diet Ad Libitum, Nutritional Standard Care
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Universidad Autonoma de Chihuahua
Reduction of Cardiovascular Risk Factors
PrevA Study - Evaluation of an App-based Nutritional Concept
The PrevA study is designed to evaluate our developed nutritional concept to implement a heart healthy diet. The nutritional concept based on nutrient-optimized daily menu plans for each study day.
- Trial name
- PrevA (NCT04717076)
- Testing
- App-based nutritional concept and fitness tracking, Nutritional concept with individual nutritional counselling, Nutritional concept without individual nutritional counselling
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jena
Cardiovascular Diseases, Cardiovascular Risk Factor
A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.
A 12-week, randomized nutrition intervention for the reduction of cardiovascular disease risk factors in a high-risk population in the southeastern United States.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Obesity
- Trial name
- HHP (NCT03683134)
- Testing
- Mediterranean diet, Olive oil and mixed nuts, American Heart Association
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Auburn University
Atherosclerotic Cardiovascular Disease, Coronary Artery Disease
The Young Heart Study
The purpose of our project is to better understand the characteristics of the young patients with coronary artery disease presenting for cardiac catheterization at our institution and to put forth a program to optimize their risk…
- Trial name
- NCT04462159
- Testing
- Risk Reduction Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Cardiovascular Disease
Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints and Outcomes
The primary objective is to show whether rimonabant reduces the risk of a heart attack (MI), stroke, or death from an MI or stroke in patients with abdominal obesity with other cardiovascular (CV) risk factors.
- Trial name
- CRESCENDO (NCT00263042)
- Testing
- Rimonabant
- Where
- 43 sites in United States, Argentina and 41 more
- Volunteers
- 18,695 people
- Sponsor
- Sanofi
Obesity, Type 2 Diabetes
Activity and Metformin Intervention in Obese Adolescents
The purpose of this study is to assess the sustainability of a two-year intervention aimed at improving body mass index (BMI) and metabolic and vascular health in obese youth.
- Trial name
- REACH (NCT00934570)
- Testing
- Metformin and standard exercise, Metformin Intensive exercise, Intensive exercise
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Diabetes Mellitus
Prevention of Postprandial Hyperglycemia by Acarbose May be a Promising Therapeutic Strategy for Reducing the Increased Risk for Cardiovascular Disease
The use of acarbose in impaired glucose tolerance (IGT) and type 2 diabetic subjects has been associated with a significant reduction of cardiovascular events.
- Trial name
- ABDOMEN (NCT01167231)
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- Poland
- Volunteers
- 3,310 people
- Sponsor
- Bayer
Inflammation, Cardiovascular Diseases
Role of Cherry Consumption in Reducing Risk Factors for Chronic Inflammatory Diseases
The goal of this study is to examine if chronic cherry consumption will decrease lipid peroxidation and serum concentration of inflammatory markers in human subjects with elevated serum C reactive protein (CRP), and to examine…
- Trial name
- NCT01734070
- Testing
- Cherry consumption
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Cardiovascular Risk Factor
Reducing Cardiovascular Risk of African Americans
Diseases such as hypertension and stroke affect mid-life and older African Americans at higher rates than Whites, negatively affecting health status of this group.
- Trial name
- NCT03339050
- Testing
- Health for Hearts United
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cannabis, Cardiovascular Risk Factor
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest and during aerobic exercise.
- Trial name
- NCT04693884
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jamie Burr
Cardiovascular Risk Factor, Lifestyle Risk Reduction
Implementation of a Structured Lifestyle Program in Primary Care. Changes in Lifestyle Habits and Cardiovascular Risk.
The aim of the present study is to describe and evaluate the effect of a structured lifestyle intervention program, focusing on lifestyle habits, in a primary care setting in patients with high cardiovascular risk.
- Conditions
- Cardiovascular Risk Factor, Lifestyle Risk Reduction, Primary Care
- Trial name
- NCT03681002
- Testing
- structured lifestyle program
- Volunteers
- 450 people
- Sponsor
- Uppsala University
Cardiovascular Risk Factor, Lifestyle Risk Reduction
The Effect of Lifestyle Intervention on Cardiovascular Disease Risk Among Women
Patient education in lifestyle changes has a positive effect on health in individuals with cardiovascular (CV) risk. Despite current positive evidence about lifestyle and dietary change in the prevention of CVD, the…
- Trial name
- NCT04601558
- Testing
- The letters with the Cochrane abstracts in the form of blog-shots, The letters with remainder on cardiovascular risk factors
- Where
- Croatia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Cardiovascular Diseases, Cardiovascular Abnormalities
The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
Cardiovascular diseases (CVD), primarily heart disease and stroke, are the leading causes of death and prescription drug use in Canada.
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Heart Attack, Stroke
- Trial name
- NCT03826914
- Testing
- CardioFlex Q10
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Diseases
Cardiovascular Disease Risk of Awareness
The Cardiovascular Risk Reduction Program (CARDIOREP) aims to raise risk awareness and reduce risk factors.
- Trial name
- NCT06000436
- Testing
- Cardiovascular disease risk assessment, Training and Consultancy, Mobile Application
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Cardiovascular Diseases
Evaluating the Effect of Neighborhood Environments on Cardiovascular Risk Factors
Cardiovascular disease (CVD) is one of the main causes of death in the United States. Research has shown that individuals who maintain an active lifestyle are less likely to develop CVD.
- Trial name
- NCT00361673
- Where
- 2 sites in United States
- Volunteers
- 1,140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes, Dyslipidemia
Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic
The purpose of this study is to determine whether a combined behavioral and pharmacological intervention provided by a multidisciplinary team will further reduce LDL-C, smoking, BP and Hb-A1C in diabetic patients with A1c between…
- Conditions
- Diabetes, Dyslipidemia, Hypertension, Coronary Atherosclerosis
- Trial name
- NCT00358033
- Testing
- Counseling, Interactive Education, Group Support
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Providence VA Medical Center