Clinical trials: Reference Values, active
Healthy
Reference Values for the One Repetition Maximum Test of Knee Extensors for Brazilians.
Muscle strength is important for health and can affect how well people live, even increasing the risk of death in adults and older people.
- Trial name
- NCT06648421
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Healthy
Non-contrast Enhanced Cardiac Magnetic Resonance Normal Values and Imaging Protocols
One of the main problems in cardiac magnetic resonance (MR) investigations is the strong dependence of the achieved image quality on optimal settings of sequence parameters and anatomical and physiological situations and it is…
- Trial name
- CMR-TECH (NCT01728597)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Uninfected Healthy Adult Subjects
REF-VALUE Study: Establishment of Reference Values for Biomarkers in Healthy Adults
Circulating biomarkers play a central role in translational research and precision medicine, particularly for the diagnosis, prognostic, monitoring of inflammatory or infectious diseases and patient stratification.
- Trial name
- REF-VALUE Stud (NCT07666191)
- Testing
- Biological Sampling
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Child Development
LIFE Child (LIFE Leipzig Research Centre for Civilization Diseases)
The Leipzig Research Centre for Civilization Diseases (LIFE) Child Study is a prospective longitudinal population-based study with a life course approach to health and disease.
- Trial name
- NCT02550236
- Where
- Germany
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Healthy Adults, Pulmonary Hypertension
A Multicenter Study on the Normal Reference Range and Clinical Significance of the Right Atrioventricular Coupling Index Assessed by Artificial Intelligence-Based Three-Dimensional Echocardiography
This multicenter study aims to establish the normal reference range of the Right Atrioventricular Coupling Index (RACI) in healthy Chinese adults using AI-based 3DE technology.
- Conditions
- Healthy Adults, Pulmonary Hypertension, Tricuspid Regurgitation, Heart Failure
- Trial name
- NCT07292896
- Where
- 25 sites in China
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Immunosenescence, Uninfected Older
Interferon Reference for Older People - REFIPA Study
The diagnosis of respiratory viral infections is mainly based on PCR tests targeting the DNA or RNA of suspected viruses, including SARS-CoV-2, RSV and influenza viruses.
- Trial name
- REFIPA (NCT07239830)
- Testing
- Uninfected older adults
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy Volunteers, Imaging Evaluation
Multimodal Cardiovascular and Hepatic Population Imaging
Medical imaging is increasingly important for understanding diseases, detecting them early, and personalizing treatments. New imaging techniques, which can measure processes in the body without surgery, are opening the door to a…
- Trial name
- ICONIC (NCT06906042)
- Testing
- Imaging examinations, Paramedical examinations, Medical examination
- Where
- France
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Dysphagia, Oropharyngeal
Reference Values for Videofluoroscopic Measures of Swallowing
Dysphagia (swallowing impairment) is a serious health condition seen in many age-related disease and injury processes. Although videofluoroscopy (VF) is an international "gold standard" dysphagia diagnostic exam, there is a…
- Trial name
- NIA_RV (NCT05497219)
- Testing
- Videofluoroscopic Swallowing Study (VF)
- Where
- 5 sites in United States, Canada
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Knee Ligament Injury
Reference Values for Knee Rotational Amplitudes in a Population of Athletes
Rupture of the anterior cruciate ligament (ACL) is a frequent and disabling injury in pivot sports, leading to knee laxity and instability, reduced performance and an increased risk of early osteoarthritis.
- Trial name
- PRELAX (NCT07013019)
- Testing
- Measures of overall (internal+external) knee rotational amplitudes
- Where
- 2 sites in France
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy Volunteer
Normal Values in Hearing and Balance Testing
Background: Researchers at the National Institutes of Health give many tests of hearing and balance. These tests can help detect problems that affect hearing or balance.
- Trial name
- NCT01629108
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Healthy Participants
Global Reference Ranges - Singapore
We aim to undertake the Global Reference Range Study (GRR) to establish a set of healthy adult reference values for measures of fibroinflammation, fat and size/volumes for the liver, and other abdominal and thoracic organs to…
- Trial name
- GRR Singapore (NCT07166471)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Perspectum
Chronic Kidney Disease on Hemodialysis
Reference Values for Lower-Limb Dynamometry in Patients With Chronic Kidney Disease (REHAD-CKD)
Patients with chronic kidney disease (CKD) undergoing hemodialysis present musculoskeletal complications, such as sarcopenia, which impair their functionality and are associated with an increased risk of mortality.
- Trial name
- REHAD- CKD (NCT07642778)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
GERD (Gastroesophageal Reflux Disease)
Normal Values of Ambulatory 24-hour Oesophageal pH-impedance Monitoring in an Indian Cohort of Participants
This study aims to determine normal 24-hour pH-impedance monitoring values, including acid exposure time (AET), in healthy Indian adults. It will help improve GERD diagnosis in India by providing population-specific data.
- Trial name
- NCT06928350
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Prostate CA
Trans and Non-binary Prostate-Specific Antigen Reference Interval Determination Study
The prostate specific antigen (PSA) blood test can help diagnose prostate problems, including cancer. The prostate is an organ in the pelvis. It is found in cisgender men, transgender (trans) women and some non-binary people.
- Trial name
- TransPRIDE (NCT06987045)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Effect of Drug
PFA 100 Evaluation and Reference Interval HOACNY
The purpose of this research is to evaluate instrument functionality and develop a reference range of normal data by healthy volunteers.
- Trial name
- NCT06100510
- Testing
- Aspirin 325mg
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hematology Oncology Associates of Central New York
Gastric Emptying, Bariatric Surgery
Reference Values for Gastric Emptying Scintigraphy After Bariatric Surgery
Oesophageal and gastric scintigraphy evaluates the function of the gastrointestinal system including variables such as oesophageal transit and gastric emptying (GE). Some variables are known to change after bariatric surgery.
- Trial name
- SCATTER (NCT06391255)
- Testing
- scintigraphy
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Iron Deficiency (Without Anemia), Reference Values
Iron Status of Non-anemic Pregnant Women in First Trimester
This cross-sectional study aims to establish reference intervals for iron biomarkers-including serum iron, ferritin, total iron-binding capacity (TIBC), and transferrin saturation (TSAT)-in healthy pregnant women during the first…
- Conditions
- Iron Deficiency (Without Anemia), Reference Values, Iron Deficiency Without Anemia
- Trial name
- NCT06990373
- Where
- Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hung Vuong Hospital
Fetal Growth Retardation, Fetal Neurodevelopmental Disorder
Fetal Magnetic Resonance Imaging: Z-score Reference Ranges for a Large Patient Population in Normal Neuroimaging Measurement
This study aims to establish the z score reference ranges of fetal head circumference and other measurement of fetal measurements including biparietal diameter, fronto-occipital diameter, length of the corpus callosum, lateral…
- Trial name
- FMZSCORE (NCT07004283)
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Pediatric, Coagulation
Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients
This study will determine reference range intervals for the parameters reported by the Quantra System with the QPlus Cartridge in pediatric patients.
- Trial name
- NCT07447713
- Testing
- Quantra System
- Where
- 4 sites in United States, Switzerland
- Volunteers
- 240 people
- Sponsor
- HemoSonics LLC