Clinical trials: Reflux Laryngitis
Gastroesophageal Reflux Disease (GERD), Chronic Laryngitis
Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis
Saliva plays a key role in the homeostasis of the digestive tract The reflux of gastroesophageal contents may cause damage to the esophageal, laryngeal and pharyngeal mucosas There seems to be no correlation between the severity…
- Trial name
- NCT01389401
- Testing
- omeprazole
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Laryngopharyngeal Reflux, Laryngopharyngitis Chronic
Method of Early Diagnosis of Laryngopharyngeal Reflux
The investigator will issue a Patient Information Consent for the participant in the study. 1.Patients will be asked to complete the Reflux Symptom Index questionnaire. Clinical survey, medical history. 2.
- Conditions
- Laryngopharyngeal Reflux, Laryngopharyngitis Chronic, Gastro Esophageal Reflux, Laryngitis
- Trial name
- LPR (NCT04771221)
- Testing
- pH metry, Filling out the questionnaire, Endoscopic laryngoscopy
- Where
- 2 sites in Kazakhstan
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Chronic Posterior Laryngitis (CPL)
Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux
This study looks at how effective acid suppression therapy is on symptoms associated with chronic posterior laryngitis (CPL) in patients with documented pharyngeal acid reflux.
- Trial name
- NCT00628667
- Testing
- Esomeprazole
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Laryngopharyngeal Reflux (LPR), Extraesophageal Reflux
Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR
The purpose of this research study is to better understand whether information obtained from a pH probe can help physicians predict whether a patient will respond to the medication that is prescribed for laryngopharyngeal reflux…
- Conditions
- Laryngopharyngeal Reflux (LPR), Extraesophageal Reflux, Reflux Laryngitis, Posterior Laryngitis
- Trial name
- NCT01755221
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic
Kazakh Version of Reflux Symptom Index
Reflux symptoms index (RSI) were developed to identify a clinical index of suspicion for laryngopharyngeal reflux (LPR) in patients with ear, nose, and throat symptoms.
- Conditions
- Laryngopharyngeal Reflux Symptoms, Laryngopharyngitis Chronic, Gastro Esophageal Reflux Disease
- Trial name
- NCT05296655
- Testing
- Reflux Symptom Index Inventory (diagnostic survey), Reflux finding score
- Where
- 2 sites in Kazakhstan
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Laryngitis, Reflux
Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists
Title: Inter-rater reliability of the reflux finding score based on endoscopic laryngeal findings in the diagnosis of laryngopharyngeal reflux disease Participants: Voluntary participants after invitation among members (a total…
- Trial name
- NCT02048449
- Volunteers
- 21 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Gastroesophageal Reflux Disease, Chronic Laryngitis
Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis
Saliva plays an important role in the homeostasis of the digestive tract mucosa. Salivary organic components, such as the Epidermal Growth Factor(EGF) have been found in defficient concentrations in patients with gastroesophageal…
- Trial name
- EGFR (NCT01806220)
- Testing
- Biopsy of the retrocrycoid laryngeal mucosa, Biopsy of the distal esophageal mucosa
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Laryngopharyngeal Reflux
Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux
The purpose of this study is to determine whether Lansoprazole 30mg taken twice daily is effective in the treatment of laryngitis due to gastroesophageal reflux.
- Trial name
- NCT00369265
- Testing
- Lansoprazole, Sugar pill
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- American Institute for Voice and Ear Research
Laryngopharyngeal Reflux
Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment
This study proposes to investigate prospectively, the presence of molecular markers for inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton pump inhibitor (Aciphex) on these molecular…
- Trial name
- NCT00204698
- Testing
- Aciphex
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Utah
Laryngopharyngeal Reflux (LPR)
Quality of Life Validation in Laryngitis
The primary purpose of this study was to establish the psychometric properties of a new disease specific Quality of Life questionnaire, the LPR-HRQL.
- Trial name
- NCT00641264
- Testing
- Omeprazole, Quality of Life questionnaire
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Gastroesophageal Reflux, Laryngitis
Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients
The purpose of this study is to evaluate the efficacy of rabeprazole (pariet) versus placebo in treating reflux laryngitis in Chinese patients.
- Trial name
- NCT00517114
- Testing
- Rabeprazole 20mg twice daily
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hospital Authority, Hong Kong