Clinical trials: Refractive Ametropia
Astigmatism, Presbyopia
North American Comfilcon A Clinical Study
The main objective of this study is to demonstrate acceptable safety and effectiveness (performance) of comfilcon A Sphere, Toric, Multifocal, Toric Multifocal and Energys lenses, when used in the general population.
- Conditions
- Astigmatism, Presbyopia, Ametropia
- Trial name
- NCT06902584
- Testing
- comfilcon A Sphere lens, comfilcon A Toric lens, comfilcon A Multifocal lens
- Where
- 4 sites in United States
- Volunteers
- 182 people
- Sponsor
- CooperVision International Limited (CVIL)
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06295536
- Testing
- Comparator device, Closed-field autorefractometer
- Where
- Hong Kong
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Essilor International
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Roflufocon D
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT02553681
- Testing
- roflufocon D contact lenses, RGP contact lenses made from roflufocon D
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Refractive Ametropia
Evaluation of the Performance of Two Contact Lenses Compared to a Marketed Lens
This study will serve to evaluate and compare the performance of two new lenses to a marketed lens.
- Trial name
- NCT01484028
- Testing
- etafilcon A control lens (1DM), etafilcon A with print and PVP for light eyes (EALE), etafilcon A with print and PVP for dark eyes (EADE)
- Where
- 15 sites in United States
- Volunteers
- 275 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Testing the Safety and Acceptability of Using a Rewetting Drop with Contact Lenses
- Trial name
- NCT00691197
- Testing
- Carboxymethylcellulose sodium and Glycerin, Carboxymethylcellulose sodium
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Allergan
Myopia, Refractive Ametropia
Comparison of Low- Versus High-Level Angle Kappa Compensation Strategies in SMILE Using the VisuMax 800: A Randomized Clinical Trial
The goal of this clinical trial is to compare two intraoperative kappa-angle compensation strategies during small incision lenticule extraction (SMILE) using the VisuMax 800 platform in patients with relatively large kappa-angle…
- Trial name
- NCT07512102
- Testing
- Apply high compensation to the Kappa angle., Apply low compensation to the Kappa angle.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Astigmatism, Ametropia
Optimization for Toric Contact Lenses
The aim of this study is to evaluate the agreement between subjective and objective toric lens prescriptions.
- Trial name
- NCT07557030
- Testing
- Lens 1 ( stenfilcon A ), Lens 2 ( comfilcon A )
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Ametropia
Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical trial is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in an extended wear modality.
- Trial name
- NCT04085328
- Testing
- LID015385 soft contact lenses, Comfilcon A soft contact lenses
- Where
- 42 sites in United States
- Volunteers
- 675 people
- Sponsor
- Alcon Research
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Ametropia, Myopia
Apioc Contact Lens Feasibility
This clinical trial will document the feasibility of the Apioc lens design by assessing which lens shape parameters yield successful on-eye-fit and movement of the Apioc contact lens design and evaluate the subjectively-reported…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03688672
- Testing
- Apioc Contact Lens Design
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Refractive Errors, Ametropia
Clinical Performance of Two Commercial, Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of DAILIES TOTAL1 ( DT1) contact lenses with Infuse contact lenses.
- Conditions
- Refractive Errors, Ametropia, Myopia
- Trial name
- NCT05010512
- Testing
- Delefilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Refractive Ametropia
A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution
Approximately 340 participants (680 eyes) will be enrolled in this three-month, two-arm, 1:1 randomized, parallel-group, bilateral, double-masked study at approximately 22 investigative sites in the United States.
- Trial name
- NCT05565937
- Testing
- BL-3100-NBR03 multi-purpose solution, renu® Advanced Formula multi-purpose solution
- Where
- 19 sites in United States
- Volunteers
- 295 people
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Study of Soft Contact Lens Use With 7 Day Extended Wear
To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses.
- Trial name
- NCT00597467
- Testing
- VISA (comfilcon A) Silicone Hydrogel Soft contact lens, Acuvue 2 Soft Contact Lens
- Where
- 23 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia, Astigmatism
Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
The purpose of this study is to assess the clinical performance of TOTAL30 for Astigmatism (T30fA) soft contact lenses with Biofinity Toric soft contact lenses.
- Trial name
- NCT06165627
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alcon Research
Ametropia
Clinical Characterization of Symptomatic Populations
This is an unmasked, non-randomized, single arm, stratified, dispensing investigation of symptomatic and asymptomatic subject populations.
- Trial name
- NCT03319212
- Testing
- senofilcon A contact lenses
- Where
- 2 sites in United States, Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Dispensing Study for the Phenacite Project
Dispensing Study for the Phenacite Project. The investigational test lens was not the final optical design and the study was not used for design validation.
- Trial name
- NCT02436005
- Testing
- Phenacite, comfilcon A
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Ametropia
Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS)
This study aimed to compare refractive measurements using Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic…
- Trial name
- REFRALENS (NCT06668246)
- Testing
- Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic refraction serving as the gold
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Brest
Myopia
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
- Trial name
- NCT06305663
- Testing
- Bausch + Lomb (kalifilcon A) Myopia Control Soft (Hydrophilic), CooperVision MiSight (omafilcon A/60%) Myopia Control one day Soft Contact Lens
- Where
- 11 sites in China
- Volunteers
- 418 people
- Sponsor
- Bausch & Lomb Incorporated
Ametropia
Three-month Clinical Evaluation of Silicone Hydrogel Definitive 65 Contact Lenses
Comparison of different contact lens materials.
- Trial name
- NCT02249689
- Testing
- Definitive 65, Definitive 74
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd