Clinical trials: Refractive Assessment
Refractive Errors, Vision Disorders
Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction
This study is exploratory and examines whether the best-corrected visual acuities (BCVA's) from trial frames created with the refraction results obtained from a novel handheld optical device yields results similar to the…
- Trial name
- NCT04693247
- Testing
- EQ103
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Axial Myopia, Refractive Errors
Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure
The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye…
- Trial name
- NCT03552016
- Testing
- Oral Riboflavin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Refractive Errors
Investigation of the Accuracy of an Automated Refractor to Provide Well-tolerated Eyeglass Prescriptions
At the New England College of Optometry in Boston, MA, subjects ages 18-65 who have received or are receiving treatment for refractive error who choose to enroll in the study will be evaluated using subjective refraction and…
- Trial name
- NCT06883032
- Testing
- AR Eyeglasses first, SR Eyeglasses second, SR Eyeglasses first, AR Eyeglasses second
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- PlenOptika, Inc.
Myopia, Refractive Errors
PiXL as a Treatment for Low Grade Myopia
To assess the improvement in myopia with phototherapeutic intrastromal corneal collagen cross-linking (PiXL) without epithelial debridement (epi-on) in high oxygen environment for low grade myopia.
- Trial name
- NCT04663048
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Umeå University
Ametropia
Three-month Clinical Evaluation of Silicone Hydrogel Definitive 65 Contact Lenses
Comparison of different contact lens materials.
- Trial name
- NCT02249689
- Testing
- Definitive 65, Definitive 74
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit.
- Trial name
- NCT05389072
- Testing
- control contact lens
- Where
- 4 sites in United States, Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT04525170
- Testing
- HPT treatment, untreated
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Eye Cyclorotation Degree, Pupil Shift
Evaluation of Position-induced Cyclorotation Between Wavefront Measurement and Refractive Surgery by the Iris Registration Method
Cyclorotation of eyes may be affected by motion and orientation of the head and body. An automated alignment method with the technique of iris recognition was used to assess the amount and orientation of position-induced…
- Trial name
- NCT00943163
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05431543
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution
- Where
- 5 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia
Visual Outcomes and Contrast Sensitivity After Myopic LASIK
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK procedure using the 200 kHz WaveLight® FS200 Femtosecond Laser and the WaveLight® Allegretto Wave® Eye-Q Laser.
- Trial name
- NCT01746589
- Testing
- bilateral myopic LASIK
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Daniel S. Durrie, MD
Myopia, Hyperopia
Clinical Investigation of the Vision-R800 Device.
Randomized, bilateral, cross-over dispensing study of a standard and VR800 refraction and associated spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT04208750
- Testing
- Vision R-800 Phoropter, Standard Phoropter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Pete Kollbaum, OD, PhD
Myopia
Safety and Effectiveness of Wavefront-Guided LASIK Corrections of Myopic Refractive Errors
The purpose of this clinical trial is to demonstrate that wavefront-guided LASIK is safe and effective for the correction of myopic refractive errors.
- Trial name
- NCT01663363
- Testing
- LASIK correction of myopic refractive errors
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refraction Error, Myopia
The MORE Study: Manifest vs. Online Refraction Evaluation
The assessment of the refractive state of the eye is a fundamental and important part of ophthalmic and optometric clinical practice.
- Conditions
- Refraction Error, Myopia, Astigmatism
- Trial name
- MORE (NCT03313921)
- Testing
- Online Manifest Refraction
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Ametropia
One-month Clinical Evaluation of Silicone Hydrogel Definitive 65 HPT Contact Lenses
Comparison of different contact lens materials.
- Trial name
- NCT02312323
- Testing
- Definitive 65 HPT contact lenses, Definitive 65 contact lenses
- Where
- 2 sites in Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Ametropia
Comparison of Two Toric Contact Lenses on Current Toric Wearers
The purpose of this study is to evaluate and compare the clinical performance of two toric contact lenses amongst 110 subjects, 2-week, single masked (subject), daily wear, randomized, bilateral, crossover study; 4 weeks…
- Trial name
- NCT00639379
- Testing
- senofilcon A toric, alphafilcon A toric
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
The objective of the study was to compare the clinical performance of the two contact lenses when used in combination with three care systems.
- Trial name
- NCT04195581
- Testing
- comfilcon A, fanfilcon A
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Moderate to High Myopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of moderate to high myopia (nearsightedness), when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762541
- Testing
- MEL 80 Treatment of High Myopia
- Where
- 5 sites in United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Refractive Ametropia, Astigmatism
1-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact Lenses
Experienced soft contact lens wearing subjects were enrolled in this 1-week, post-market, bilateral, repeated measures, dispensing study.
- Trial name
- NCT06053736
- Testing
- REVIVE Toric Soft Contact Lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated