Clinical trials: Refractive Error
Myopia, Presbyopia
Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials
The purpose of this study was to compare visual performance measures between two multifocal contact lenses on presbyopic wearers.
- Trial name
- NCT01371539
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 109 people
- Sponsor
- CIBA VISION
Myopia
Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers
This study was a multi-site, prospective, randomized, non-masked, unilateral, non-dispensing study.
- Trial name
- NCT04886479
- Testing
- Control, Test Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Stable Myopic Refractive Error, With or Without Astigmatism
Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.
- Trial name
- NCT02675751
- Testing
- STAR S4 IR laser with iDesign
- Volunteers
- 167 people
- Sponsor
- Abbott Medical Optics
Myopia
A One-Week Crossover Dispensing Evaluation of New Daily Wear Soft Contact Lenses
The purpose of this study is to validate the clinical performance of a new contact lens design when worn over a period 1 week compared to nelfilcon A (control).
- Trial name
- NCT03306641
- Testing
- Test Contact Lens, Nelfilcon A
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Presbyopia
A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses
The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.
- Trial name
- NCT02719366
- Testing
- comfilcon A Extended Range test lens, comfilcon A control lens
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
The purpose of this study was to assess and compare the effect of the repeated usage of 2 different care systems (one hydrogen peroxide based cleaning and disinfecting system and one PHMB containing multipurpose system) with…
- Trial name
- ID11-56 (NCT01594294)
- Testing
- AOSEPT® Plus contact lens solution, ReNu MultiPlus® contact lens solution, Etafilcon A contact lenses
- Volunteers
- 100 people
- Sponsor
- Alcon Research
Myopia
DW Evaluation of Lotrafilcon B Lenses in a Modified Design
The purpose of this study is to demonstrate that Lotrafilcon B AIR OPTIX® AQUA sphere modified design lenses are noninferior to Lotrafilcon B AIR OPTIX® AQUA in overall lens fit by comparing the percent of subjects satisfying the…
- Trial name
- NCT02157909
- Testing
- Lotrafilcon B sphere modified design contact lenses, Lotrafilcon B sphere contact lenses
- Volunteers
- 134 people
- Sponsor
- Alcon Research
Refractive Error
Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial was to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
- Trial name
- NCT01198600
- Testing
- Habitual contact lens, Lotrafilcon B contact lens, Contact lens cleaning and disinfecting system (ClearCare)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- CIBA VISION
Myopia
Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.
- Trial name
- NCT01362907
- Testing
- Delefilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION
Myopia
Lens Wear Schedules and End-of-Day Comfort
The purpose of this study was to assess the impact of lens-free (recovery) intervals of varying lengths on end-of-day comfort and tear film changes with daily contact lens wear.
- Trial name
- INVERMERE (NCT01433549)
- Testing
- Lotrafilcon B, Senofilcon A
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CIBA VISION
Myopia
Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression Rate
Our project is a 24-month longitudinal randomized controlled trial that aims to investigate the myopia development after topical application of 0.01% atropine in children with either fast or slow myopia progression classified…
- Trial name
- NCT03374306
- Testing
- Atropine (0.01%), Artificial tear
- Where
- Hong Kong
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
To evaluate the performance of two monthly replacement silicone hydrogel contact lenses in habitual FRP CL wearers when worn for 1-month.
- Trial name
- NCT05333965
- Testing
- Lens A (lehfilcon A lens), Lens B (comfilcon A lens)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Multifocal Contact Lenses Fitting Methods Comparison
The purpose of this study was to compare the clinical performance of two fitting approaches for multifocal contact lenses.
- Trial name
- NCT05734846
- Testing
- Control Lenses (control fitting approach), Test Lenses (test fitting approach)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Myopia
Use of the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT01638390
- Testing
- Treatment with the VisuMax™ Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Myopia
Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366923
- Testing
- stenfilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
An evaluation of the clinical performance of the 1-day toric test contact lens compared to the 1-day toric control contact lens over one hour of lens wear.
- Trial name
- NCT04016623
- Testing
- 1-day toric test contact lens, 1-day toric control contact lens
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Astigmatism
Clinical Evaluation of Two Toric Contact Lenses in Current Non-toric Lens Users
The purpose of this study is to evaluate the clinical performance, defined as successful fit, of two toric contact lenses (one daily disposable and the other daily wear reusable contact lens to correct astigmatism) in current…
- Trial name
- NCT01180998
- Testing
- Senofilcon A Toric (AOfA), Etafilcon A Toric (1DAMfA)
- Where
- 18 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
The purpose of this study was to describe mean differences in corneal staining (type and area) for OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS) at Day 30 compared to Baseline (Day 0).
- Trial name
- NCT01484938
- Testing
- OPTI-FREE PureMoist
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Alcon Research
Myopia
Clinical Performance Comparison of Two Contact Lenses
The purpose of this study is to compare the clinical performance of two contact lenses.
- Trial name
- NCT00975585
- Testing
- senofilcon A, lotrafilcon B
- Where
- 25 sites in United States
- Volunteers
- 379 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics