Clinical trials: Refractive Error - Myopia
Myopia
Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.
The purpose of the study is to quantify the effectiveness of CooperVision MiSight® (omafilcon A) soft (hydrophilic) contact lens in slowing the rate of progression of juvenile-onset myopia.
- Trial name
- NCT01917110
- Testing
- omafilcon A, Spectacle
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- CooperVision, Inc.
Myopia
Tolerability of a Novel Spectacle Design With Reduced Peripheral Contrast
Prospective, randomized, subject-masked 3-arm clinical study to assess the pediatric acceptability across three iterations of a novel spectacle lens design.
- Trial name
- WALNUT (NCT03761758)
- Testing
- Spectacle lenses
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia, Myopia Progression
Spectacle Lens Visual Acuity Assessments Study
This is a two-arm parallel group, non-dispensing study. Participants will be existing active CYPRESS Extension (CPRO-1802-002) subjects. Subjects will undergo additional visual performance assessments.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- CEDAR (NCT05650190)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 6 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia, Astigmatism
Use of a Disk of Amniotic Membrane (Visio-AMTRIX) in Postoperative Care After PKR
The purpose of this open controlled multicenter trial is to assess the impact of use of an amniotic membrane on post PKR recovery.
- Conditions
- Myopia, Astigmatism, Hypermetropia
- Trial name
- NCT05247658
- Testing
- Therapeutic lens alone, Therapeutic lens + amniotic membrane (Visio-AMTRIX)
- Where
- 3 sites in France
- Volunteers
- 9 people
- Sponsor
- TBF Genie Tissulaire
Myopia
Clinical Trial of Orthokeratology Lens (MCOK-01)
A prospective, multicenter, randomized, controlled clinical trial of orthokeratology lens
- Trial name
- NCT06037850
- Testing
- Test orthokeratology lens, Control orthokeratology lens
- Where
- 3 sites in Singapore
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia and Hyperopia and Presbyopia
Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens
The objective of this study is to evaluate the product performance of a new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens, when worn by…
- Trial name
- NCT05660577
- Testing
- new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens
- Where
- 20 sites in United States
- Volunteers
- 301 people
- Sponsor
- Bausch & Lomb Incorporated
Juvenile Myopia
Myopia Assessment of Two Manufacturing Processes
Randomized, controlled, multisite, subject- and observer-masked, contralateral clinical trial of 6-month duration to compare two SightGlass Vision Diffusion Optics Technology (DOT) spectacle lens manufacturing processes in…
- Trial name
- MAPLE (NCT04126057)
- Testing
- SightGlass Vision DOT Spectacle Lenses
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
The purpose of this study was to compare a new daily disposable, silicone hydrogel contact lens to marketed daily disposable, silicone hydrogel contact lenses.
- Trial name
- TUNGSTEN (NCT01371552)
- Testing
- delefilcon A contact lens, filcon II 3 contact lenses, narafilcon A contact lenses
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- CIBA VISION
Myopia
Two Week Cross-Over Study Comparing Two Daily Disposable Contact Lenses
This study seeks to evaluate and compare the clinical performance of two daily disposable soft contact lenses, Proclear 1 Day and 1-Day Acuvue Moist.
- Trial name
- NCT01155323
- Testing
- etafilcon A, omafilcon A
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits.
- Trial name
- VISION-2 (NCT05114486)
- Testing
- Pilocarpine Ophthalmic administered with the Optejet dispenser
- Where
- 9 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia
Effects of Projected Peripheral Defocus on Ocular Biometrics
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04388020
- Testing
- Tabletop prototype of eSpecs: Active projection of defocused image in the peripheral visual field, Tabletop prototype of eSpecs: No Active projection of defocused image in the peripheral visual field
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Astigmatism, Myopia
Comparative Clinical Evaluation of Soft Toric Lens Designs
This study is evaluating the initial fit of toric contact lenses.
- Trial name
- NCT01552876
- Testing
- etafilcon A, nelfilcon A, Filcon II 3
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Study of safety and efficacy of UNR844 in subjects with presbyopia.
- Trial name
- READER (NCT04806503)
- Testing
- UNR844
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 234 people
- Sponsor
- Novartis Pharmaceuticals
Myopia
Clinical Evaluation of the Safety and Efficacy of Yung Sheng 38% Color Contact Lens
This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 38% color contact lens for vision correction.
- Trial name
- NCT06128473
- Testing
- Soft Contact Lens
- Volunteers
- 71 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Myopia
Comparison of Somofilcon A Daily Disposable Test Contact Lens and Somofilcon A Daily Disposable Control Contact Lens
The purpose of this study is to investigate the overall clinical performance of the somofilcon A daily disposable test soft contact lens compared to the somofilcon A daily disposable control soft contact lens.
- Trial name
- NCT03372551
- Testing
- somofilcon A 1 day test lens, somofilcon A 1 day control lens
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- CooperVision, Inc.
Myopia
Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor) of Color Soft Contact Lenses.
Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor)of Color Soft Contact Lenses
- Trial name
- NCT02299869
- Testing
- Verde (Competitor-control), Green (CVI-test), Cinza (Competitor-control)
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Presbyopia, Myopia
Intrastromal Correction of Ametropia by a Femtosecond Laser
This study evaluates the intrastromal correction of ametropia with a femtosecond laser made by 20/10 PERFECT VISION. This laser generates a beam of ultrashort, infrared pulses which enables very precise cuts in the cornea.
- Conditions
- Presbyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- ISCAF (NCT00928122)
- Testing
- Intrastromal Correction of Presbyopia, Intrastromal correction of Myopia, Intrastromal Correction of Hyperopia
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- 20/10 Perfect Vision