Clinical trials: Refractive Error - Myopia
Nearsightedness
Effect of Defocus in Soft Contact Lenses on Internal Retinal Vascularization
The purpose of this study is to gain a better understanding of the retinal vascular changes that occur in response to the optical effect of a myopic defocus daily disposable soft contact lens (MDSL) in a group of healthy young…
- Trial name
- NCT06527274
- Testing
- Experimental: Myopic defocus soft lens design (MDSL), Active Comparator: Single vision soft lens design (SVSL
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Myopia, Astigmatism
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2.
- Trial name
- NCT07201298
- Testing
- Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Myopia, Progressive
DIMS-myopia Progression ADN Axial Length Growth
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective randomized controlled clinical study.
- Trial name
- NCT05300321
- Testing
- frame lens
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Hyperopia
Creating LASIK Flaps With the LenSx Femtosecond Laser
This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility.
- Trial name
- NCT01556893
- Testing
- LenSx Laser
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alcon LenSx, Inc.
Myopia, Myopic Astigmatism
Optical Quality, Threshold Target Identification, and Military Target Task Performance After Advanced Keratorefractive Surgery
To determine the effect of two types of wavefront modalities (WFG vs. WFO) and two types of refractive surgery (PRK vs. LASIK) on visual and military task performance after laser refractive surgery.
- Trial name
- NCT01097525
- Testing
- WFG PRK, WFG LASIK, WFO PRK
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Fort Belvoir Community Hospital
Myopia, Astigmatism
Compare Anterior Chamber Biometry in Healthy and Post-LASIK Patients
In this study, the investigators employed Visante-OCT (Carl Zeiss, USA), an anterior chamber optical coherence tomography, to monitor the change of anterior chamber dimensions.
- Trial name
- NCT00838734
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Myopia
Retinal Oxygen Metabolism in Children With Myopia
The aim of the present study is to gain more information about retinal functional parameters in myopic children in Europe. For this purpose, a prospective case-control study in children aged between 8 and 13 years, as this is the…
- Trial name
- NCT07473401
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Myopia
To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
To evaluate the performance of two monthly replacement silicone hydrogel contact lenses in habitual FRP CL wearers when worn for 1-month.
- Trial name
- NCT05333965
- Testing
- Lens A (lehfilcon A lens), Lens B (comfilcon A lens)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation Of The Fitting Success Rate Of Senofilcon A Soft Contact Lenses In Three Designs.
This study will compare the on-eye fitting characteristics of three types of contact lenses. Each lens pair will be worn for 30 to 45 minutes before assessment and the results will be compared to mathematically calculated fitting…
- Trial name
- NCT03384628
- Testing
- First pair Senofilcon A contact lens, Second pair Senofilcon A contact lens, Third pair Senofilcon A contact lens
- Where
- 2 sites in United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Graeme Young
Glaucoma, Myopia
Corrected Measurement of the Retinal Nerve Fiber Layer Thickness by Optic Disc Configuration With the Cirrus HD OCT
Because the measurement of the retinal nerve fiber layer thickness is very sensitive to the position of measurement, it may be incorrect in patients with the tilted disc.
- Trial name
- NCT00741130
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pathological Myopia
Genomewide Screening of Pathological Myopia
The purpose of this study is to evaluate the possible candidate gene of pathological myopia
- Trial name
- NCT00155753
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia
Retardation of Myopia in Orthokeratology
The primary aim of this study is to evaluate and compare the eyeball elongation in children wearing orthokeratology lenses and single-vision spectacles.
- Trial name
- ROMIO (NCT00962208)
- Testing
- orthokeratology lenses, single-vision spectacle lenses
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Strabismus
Evaluation of a County-Based Eye Health Service Model in Rural Chinese Children
This project proposes to conduct a prospective, multicenter registry study in rural China to evaluate, under real-world conditions, the implementation effectiveness of an integrated child eye health service model centered at the…
- Conditions
- Myopia, Strabismus, Eye Health
- Trial name
- NCT07547748
- Testing
- School-based Eye Health Screening
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Axial Length, Myopia
China Children Eye Study
The primary objective of this multi-center, observational study is to establish the reference ranges of axial length in Chinese children and adolescents.
- Conditions
- Axial Length, Myopia, Child Development
- Trial name
- CCES (NCT05770661)
- Where
- 2 sites in China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Does Pupil Size Matters in Refractive Surgery?
To determine the influence of pupil size in refractive surgery. If any influence exist.
- Trial name
- NCT01678729
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Primary Open Angle Glaucoma, Myopia
Diagnostic Innovations in Glaucoma Study
The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye…
- Trial name
- DIGS (NCT00221897)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Myopia
Effects of Projected Peripheral Defocus on Ocular Biometrics
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04388020
- Testing
- Tabletop prototype of eSpecs: Active projection of defocused image in the peripheral visual field, Tabletop prototype of eSpecs: No Active projection of defocused image in the peripheral visual field
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia
Adaptation To and Satisfaction With Contact Lens Wear In Myopic Young Adults
The purpose of this study was to assess whether young adults could adapt to and achieve satisfaction with a daily disposable contact lens.
- Trial name
- NCT04857723
- Testing
- daily disposable contact lens
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.