Clinical trials: Refractive Error - Myopia
Myopia, Astigmatism
A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and…
- Trial name
- NCT00365677
- Testing
- The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm, The Bausch & Lomb Zyoptix Tissue Saving algorithm
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Keratitis, Myopia
Safety of Overnight Corneal Reshaping Lenses
This retrospective chart review study compares the incidence of corneal inflammation due to infection in children vs. adult patients wearing overnight corneal reshaping lenses.
- Trial name
- NCT01272271
- Volunteers
- 1,317 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle Lenses
The goal of this study is to investigate the short-term changes in choroidal thickness and efficacy of the study spectacle lenses in children.
- Trial name
- NCT07547072
- Testing
- Modified Defocus Incorporated Multiple Segments lens (D1), Modified Defocus Incorporated Multiple Segments lens (D2)
- Where
- Hong Kong
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.
Myopia, Astigmatism
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT02430428
- Testing
- Carl Zeiss Meditec VisuMax Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging
Shanghai Eye Study for Adults
Blindness and visual impairment severely impact the visual health and life quality of people, particularly the 2.566 million senior citizens aged at 65 and above in Shanghai.
- Trial name
- SESA (NCT03455478)
- Testing
- spectacles
- Where
- China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors, Astigmatism
Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses
This is a multicenter study to evaluate the clinical performance of the SynergEyes A2 lens in patients with refractive errors with or without astigmatism.
- Trial name
- NCT01058629
- Testing
- SynergEyes A2 Hybrid Contact Lens
- Where
- 10 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- SynergEyes, Inc.
Myopia
Bromday Versus Nevanac Eye Drops to Control Pain Following Photorefractive Keratectomy
This study will compare the effect of two topical non-steroidal antiinflammatory agents to control pain after photorefractive keratectomy (PRK) eye surgery.
- Trial name
- NCT01475877
- Testing
- Bromfenac
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virdi Eye Clinic
Myopia
Myopia Control With a Innovative Spectacle Lens
The purpose of this study is to demonstrate that the test spectacle lens is safe and effective in slowing myopia progression in children.
- Trial name
- NCT05174780
- Testing
- innovative myopia control spectacle lens, Single vision spectacle lens
- Where
- 9 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopia Progression
Spectacle Lens Visual Acuity Assessments Study
This is a two-arm parallel group, non-dispensing study. Participants will be existing active CYPRESS Extension (CPRO-1802-002) subjects. Subjects will undergo additional visual performance assessments.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- CEDAR (NCT05650190)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 6 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers
This study was a multi-site, prospective, randomized, non-masked, unilateral, non-dispensing study.
- Trial name
- NCT04886479
- Testing
- Control, Test Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
A Comprehensive Assessment of Anterior Corneal Power by Different Devices
To comprehensively assess the precision and agreement of anterior corneal power measurements using 8 different devices.
- Trial name
- NCT01587287
- Testing
- Corneal power measurement
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia, Cornea
Euclid Phoenix Lens Design Trial 2
Lens wettability and subjective comfort of Euclid orthokeratology lenses with and without an enhanced coating will be compared in 50 children. Axial elongation will be monitored in pediatric patients who qualify and consent.
- Trial name
- NCT06392607
- Testing
- Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia (Disorder), Astigmatism
Optical Quality of the Cornea in Orthokeratology
Analyzing Optical Quality After the Use of Overnight Orthokeratology (Ortho-K)
- Trial name
- COPCORTO (NCT06775509)
- Testing
- Ortho-K
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Myopia
Safety and Efficacy of Defocus Distributed Multi-point Lens in Myopia Control
Evaluate the safety and effectiveness of experimental group by comparing with the control group
- Trial name
- NCT05340699
- Testing
- Defocus Distributed Multi-point lens, Single vision lens
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Eye--Refractive Errors
Effect of Using Myopia Prediction Algorithm
In this study, the investigators aim to perform a prospective, randomized controlled study to compare the myopia development between children using myopia prediction algorithm and children without using myopia prediction…
- Trial name
- NCT04005014
- Testing
- Myopia prediction algorithm
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Myopic Astigmatism
Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
The objectives of this study are to evaluate the safety and efficacy of a treatment regimen for high myopia and myopic astigmatism: LASIK followed by crosslinking performed with the KXL Crosslinking-System and VibeX Xtra…
- Conditions
- Myopia, Myopic Astigmatism, Crosslinking, Corneal Ectasia
- Trial name
- NCT03913338
- Testing
- LasikXtra, LASIK
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Myopia, Astigmatism
New Treatment Algorithm to Reduce Spherical Aberration After LASIK Correction for Myopia
The purpose of this clinical trial is to demonstrate that treatments generated by an investigational algorithm reduces spherical aberration compared to currently available iDesign treatments.
- Trial name
- NCT01988415
- Testing
- VSS-Rx1 OPM vs Commercial iDesign Treatment
- Where
- Colombia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Healthy, Myopia
Ocular Imaging With Spectral Domain Optical Coherence Tomography
The purpose of this study is to analyze macular retinal thickness and macular volume using the spectral domain - optical coherence tomography (SD-OCT) in normal eyes and in eyes with various ocular diseases.
- Conditions
- Healthy, Myopia, Hypermetropia
- Trial name
- NCT00926549
- Testing
- Spectral domain-OCT (Cirrus™ HD-OCT, Carl Zeiss Meditec AG)
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yonsei University