Clinical trials: Refractive Error - Myopia
Myopia, Progressive
Choroidal Response to Novel Spectacle Lens to Control Myopia Progression
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
- Trial name
- CHERRY (NCT03818880)
- Testing
- Novel spectacle lens design
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia Progressing
3D Designed Defocus Lenses on Myopia Control in Children and Adolescents
This study aims to evaluate the effectiveness of lenses with 3D Designed Defocus in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective design, and apply personalized…
- Trial name
- NCT07284147
- Testing
- Defocus Lenses
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Progressive
DIMS-myopia Progression ADN Axial Length Growth
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective randomized controlled clinical study.
- Trial name
- NCT05300321
- Testing
- frame lens
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Astigmatism
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
We are enrolling participants aged 22 and older to have LASIK surgery in both eyes. We will perform wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye of each participant.
- Trial name
- NCT07078799
- Testing
- LASIK
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia, High Myopia
Orthokeratology for High Myopia (OHM) Study
This project aims to investigate/examine high myopic subjects on full correction ortho-k (using Topaz ortho-k lenses for high myopia) compared to subjects undergoing partial reduction ortho-k and their relationship with myopia…
- Trial name
- NCT03881358
- Testing
- ortho-k lenses and thinner spectacles, newly designed ortho-k lenses
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Astigmatism, Myopia
Vision Stability and Preference for Soft Toric vs. Soft Spherical Contact Lenses
The principal hypothesis is to be tested in this work is that vision stability (the primary outcome measure) with a spherical contact lens correction vs. a toric contact lens correction will be the same.
- Trial name
- NCT04536571
- Testing
- Test Contact lens, Control Contact lens
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Changes in Eye Shape With Myopia Management Interventions
The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses.
- Trial name
- NCT06450132
- Testing
- Atropine Ophthalmic, MiSight 1-day disposable contact lenses
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Astigmatism
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT02430428
- Testing
- Carl Zeiss Meditec VisuMax Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Axial Length, Eye, Myopia
Study on the Impact of Desk and Chair Adaptation Intervention on the Occurrence and Development of Myopia in Primary School Students
This study is a randomized controlled trial of a desk and chair adaptation intervention involving primary school students and their parents or primary caregivers.
- Conditions
- Axial Length, Eye, Myopia, Myopia Progression
- Trial name
- NCT06623760
- Testing
- Desk and chair adaptation interventions
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Near Vision
Evaluation of Near Visual Acuity With ODYSIGHT, a Smartphone Based Medical App in Comparison to a Standardized Method
This study evaluates the level of agreement between visual parameters tested using OdySight, a mobile application, and standards in office methods.
- Trial name
- TIL-001 (NCT03457441)
- Testing
- Standards vision tests, OdySight medical application assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tilak Healthcare
Myopia
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
- Trial name
- NCT03516357
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Performance of Somofilcon A Over One Week in Wearers Adapted to Omafilcon A
The objective of the study is to determine if habitual or adapted contact lens wearers of Omafilcon A can be confidently refit into Somofilcon A lenses and be successful after one week of daily wear.
- Trial name
- NCT03226353
- Testing
- somofilcon A, omafilcon A
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Emmetropization, Myopia
Focus-out Glasses on Emmetropization in Chinese Children
The purpose of this study is to characterize the effects of peripheral focous-out glasses on emmetropization in non-myopic Chinese Children Aged 6-8 Years.This is a prospective, parallel-controlled randomized trial.
- Conditions
- Emmetropization, Myopia, Hyperopia
- Trial name
- NCT05689567
- Testing
- DEFOG glasses(peripheral focus-out glasses)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Myopia
Evaluation of Two Daily Disposable Contact Lenses.
The objective of this clinical study is to evaluate the product performance of SofLens daily disposable contact lenses packaged in the investigational Test solution versus SofLens daily disposable contact lenses packaged in…
- Trial name
- NCT01300065
- Testing
- Experimental- Soflens, Marketed - Soflens
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
The Incidence and Progression of Myopia: Cohort Study
A cohort study on incidence and progression of myopia in a group of medical students
- Trial name
- NCT03244670
- Testing
- Observation study only, no specific intervention
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)