Clinical trials: Refractive Error - Myopia
Myopia
Clinical Evaluation of an Investigational Soft Contact Lens
The purpose of this 4-week dispensing trial is to evaluate and compare an investigational soft contact lens worn on a daily disposable basis with three other soft contact lenses also worn on a daily disposable basis.
- Trial name
- NCT01254747
- Testing
- Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus)
- Where
- 2 sites in United States, Germany
- Volunteers
- 130 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
A Bilateral Dispensing Clinical Trial of Sapphire Lens Against Senofilcon A Lens Over 2 Weeks
To evaluate the clinical performance of an investigational silicone-hydrogel lens when worn on a daily wear modality over two weeks of lens wear.
- Trial name
- NCT02345811
- Testing
- Sapphire, senofilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 34 people
- Sponsor
- CooperVision, Inc.
Myopia
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
- Trial name
- NCT06305663
- Testing
- Bausch + Lomb (kalifilcon A) Myopia Control Soft (Hydrophilic), CooperVision MiSight (omafilcon A/60%) Myopia Control one day Soft Contact Lens
- Where
- 11 sites in China
- Volunteers
- 418 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Randomized Controlled Trials
Effect of a Myopia Prediction System on Myopia Prevention and Control
The global rise in myopia, particularly among children and adolescents in China, underscores the inadequacy of current prevention strategies, indicating that conventional screening and education alone are insufficient to curb the…
- Conditions
- Myopia, Randomized Controlled Trials, Artificial Intelligence (AI)
- Trial name
- NCT06633393
- Testing
- Feedback on Predicted High Myopia Risk at Age 18 Using the Myopia Prediction System, Feedback on Ophthalmic Examinations
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Presbyopia
A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia
The purpose of this study is to determine whether EV06 Ophthalmic Solution is safe and effective in improving distance corrected near vision in people who have presbyopia.
- Trial name
- NCT02516306
- Testing
- EV06 Ophthalmic Solution
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Encore Vision, Inc.
Myopia
Evolution of Ocular Growth in Myopic Children: A Prospective Cohort Study
Myopia and high myopia are the leading causes of visual impairment and blindness worldwide. The total number of myopic people globally was estimated to be 2.6 billion in 2020, and it could reach 4.8 billion by 2050 unless…
- Trial name
- PREMYOM1000 (NCT06895044)
- Testing
- ophtalmologic follow-up, ophtalmological follow-up
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Myopia
Investigation of the Clinical Performance of Silicone Hydrogel Contact Lenses During Continuous Wear
The primary purpose of this study is to investigate the clinical performance of a new silicone hydrogel contact lens during continuous wear (up to 30 nights) over a period of 24 months.
- Trial name
- NCT00346593
- Testing
- Silicone hydrogel contact lens
- Where
- Australia
- Sponsor
- University of Melbourne
Myopia
Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive Keratectomy
A Study to Investigate the Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia with or without Astigmatism by Transepithelial Photorefractive Keratectomy
- Trial name
- NCT06618547
- Testing
- TENEO 317 Model 2 excimer laser
- Volunteers
- 140 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Moderate, Myopic Astigmatism
A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable Lenses
Primary Objective: To compare the efficacy and the residual refractive error of EYECRYLTM Phakic toric versus Visian® Toric ICL in moderate to high myopic patient with co-existing astigmatism.
- Conditions
- Myopia, Moderate, Myopic Astigmatism, Myopia, Degenerative
- Trial name
- NCT06839898
- Testing
- EYECRYLTM Phakic Toric Intraocular Lens Treatment Arm, Visian® Toric ICL Treatment Arm
- Where
- 4 sites in Germany, India
- Volunteers
- 172 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Myopia
Intravitreal Bevacizumab and Low Fluence Photodynamic Therapy
The purpose of this study is to report the treatment effect and safety of combined intravitreal bevacizumab (IVB) and photodynamic therapy (PDT) with verteporfin using a reduced (RF) light fluence rate, in choroidal…
- Trial name
- NCT00802126
- Testing
- Combination therapy "IVB + rf-PDT"
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- University of Campania Luigi Vanvitelli
Refractive Error, Myopia
Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
The purpose of this study is to evaluate lens centration and subjective impressions of DAILIES® AquaComfort Plus® (DACP) lenses compared to 1-DAY ACUVUE® MOIST® (1DAM) lenses in ball sports players.
- Conditions
- Refractive Error, Myopia, Myopic Astigmatism
- Trial name
- NCT02103309
- Testing
- Nelfilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Hyperopia, Myopia
A Clinical Comparison of Two Soft Contact Lenses (C24-755)
The aim of this study is to compare the short-term clinical performance of two soft contact lenses.
- Trial name
- NCT06758076
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Pseudophakia, Myopia
Treatment of Residual Myopic Refraction After 6 Months on Pseudophakic Patients Using Relex-Smile
The aim of this study is to assess visual and refractive outcomes after laser vision correction (LVC) - ReLex Smile to correct residual myopic refraction after 6 months of pseudophakic (IOL) implantation.
- Trial name
- Relex-Smile (NCT04693663)
- Testing
- Relex-Smile surgery
- Where
- Kosovo
- Volunteers
- 20 people
- Sponsor
- Eye Hospital Pristina Kosovo
Myopia, Astigmatism
Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis
The aim is to evaluate the short-term changes in ocular surface measures and tear inflammatory mediators after lenticule extraction (FLEx) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) procedures.
- Trial name
- NCT02550353
- Testing
- lenticule extraction, femtosecond laser-assisted laser in situ keratomileusis
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Myopia, Progressive
Novel Lenses for Myopia Progression Trial
This is a multi-center , prospective, randomised, longitudinal study to evaluate rate of myopia progression with novel lenses compared to Single-Vision spectacles.
- Trial name
- NCT06563700
- Testing
- spectacle lens, single vision lens
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses
The purpose of this study is to evaluate corneal swelling, limbal redness, and endothelial bleb response to wearing galyfilcon A lenses in asian eyes.
- Trial name
- NCT01482819
- Testing
- galyfilcon A, galyfilcon A plus, lotrafilcon A
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
The Model Building and Empirical Research of Eye Health Interventions for Children
The purpose of this study is to determine whether Eye Health Intervention can obviously reduce and delay myopia onset and development and improved the awareness rate of knowledge apparently .
- Trial name
- NCT02903628
- Testing
- eye health education
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Myopia, Hyperopia
Corneal Asphericity Adjustment (Q Adjustment) in Myopic and Hyperopic Patients Undergoing Refractive Correction With Excimer Laser
To study the postoperative results in myopic and hyperopic eyes treated with two different laser ablation algorithms (STD and F-CAT), both FDA approved.
- Trial name
- NCT01296867
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia, Astigmatism
A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and…
- Trial name
- NCT00365677
- Testing
- The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm, The Bausch & Lomb Zyoptix Tissue Saving algorithm
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Refractive Errors
The Effect of the Free-toroidal Design Lenses on the Subjective Visual Quality in the Myopic Population
A prospective, self-control, double-blind design was conducted in Tianjin. Two hundred participants were assigned to wear two kinds of spectacle glasses.
- Trial name
- NCT05684302
- Testing
- The free-toroidal design lenses
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tianjin Eye Hospital
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