Clinical trials: Refractive Error - Myopia Axial
Myopia
Myopia:the Role of Cone Opsin Mutations & Glasses That Control Axial Elongation
1. To determine the effect of spectacles with a red blocking filter on myopia progression in children. 2. To determine the effect of spectacles with a holographic diffuser that spreads incident light rays over an angle of 0.5…
- Trial name
- NCT01923675
- Testing
- Spectacles with red-blocking tint, Spectacles with holographic diffuser and color neutral tint, Spectacles with holographic diffuser and red-blocking tint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Washington
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Progressive
Myopia Preventing With Distance-image Screen
This study is for testing the efficacy and safety of distance-image screens for preventing myopia in children for 12 month. Each subjects would be asked to paired test the ocular parameters between before and after 12-month…
- Trial name
- DIS (NCT06088225)
- Testing
- distance-image screen
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia, Refractive Errors
School-based Myopia Control Trial for Children With Premyopia or Myopia
This is a prospective, school-based randomized controlled trial designed to evaluate auricular acupressure combined with defocus spectacle lenses for myopia control in primary school students with premyopia or myopia.
- Trial name
- SPARK (NCT07746778)
- Testing
- Defocus Spectacle Lenses, Auricular Acupressure
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia Progression, Atropine
Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia Progression
Myopia is one of the fastest-growing ocular disorders worldwide and has become a major public health concern, especially among children and adolescents.
- Trial name
- NCT07626892
- Testing
- Atropine sulphate eye drop 0.01%, Atropine sulphate eye drop 0.03%, Atropine sulphate eye drop 0.05%
- Where
- Pakistan
- Volunteers
- 95 people
- Sponsor
- Khyber Medical College, Peshawar
Refractive Errors, Hyperopia
School-based Myopia Prevention Trial for Children With Insufficient Hyperopic Reserve
This is a prospective, school-based randomized controlled trial designed to evaluate auricular acupressure for myopia prevention in non-myopic primary school students with insufficient hyperopic reserve.
- Conditions
- Refractive Errors, Hyperopia, Myopia
- Trial name
- SPARK (NCT07746804)
- Testing
- Auricular Acupressure, Eye Health Education
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Axial Length, Myopia
China Children Eye Study
The primary objective of this multi-center, observational study is to establish the reference ranges of axial length in Chinese children and adolescents.
- Conditions
- Axial Length, Myopia, Child Development
- Trial name
- CCES (NCT05770661)
- Where
- 2 sites in China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Axial Length, Myopia
Study of the Intervention Effect of Outdoor Activity Period Patterns in Promoting Myopia Among Preschool Children
This study is a randomized controlled trial based on outdoor activity interventions at specific time periods, involving preschool children aged 4 to 5 years.
- Trial name
- NCT06607640
- Testing
- Increase outdoor activity time during specific time periods
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Myopia, Progressive
Near Horizontal Heterophoria in Chinese Children
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children.
- Trial name
- NCT05007626
- Testing
- axial length and refractive error
- Where
- China
- Volunteers
- 15,081 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Progressive
Contact Lens and Myopia Control in Optometry School Students
The purpose of the study is to determine the effect of Natural View Multifocal lenses, a soft multifocal lens, on retardation of myopia in an optometric student population. Close up work (i.e.
- Trial name
- NCT04334369
- Testing
- Proclear Single Vision Contact Lenses manufactured by CooperVision, Proclear Multifocal Contact Lenses manufactured by CooperVision
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jeff Rabin
Myopia
Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia Progression
The goal of this exploratory clinical trial is to evaluate the efficacy and safety of a test spectacle lens (standard single vision lens (SVL) during first year, and standard myopia control lens (MCL) in second year), designed…
- Trial name
- NCT06850168
- Testing
- SVL, SVL with passive red-light emission, MCL
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Essilor International
Myopia, Progressive
Stellest Lens Wear in Adult Progressing Myopes
It is expected that myopia progression stabilises in the late teenage years, however, some studies report that myopia progression continues through early adulthood in as many as one third of myopes.
- Trial name
- SWAP (NCT06520124)
- Testing
- Essilor® Stellest® spectacle lens, Single-vision spectacle lens
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Myopia, Myopia Progression
The A.R.R.E.S.T.® Spectacle Film Study
The goal of this clinical trial is to learn if spectacle films using Active Reconfiguration in Retinal Encoding of Spatio-Temporal (A.R.R.E.S.T.®) signal technology works to slow down the rate of myopia progression in myopic…
- Trial name
- NCT06692699
- Testing
- Single vision spectacle lens, A.R.R.E.S.T. spectacle film
- Where
- Vietnam
- Volunteers
- 123 people
- Sponsor
- nthalmic Pty Ltd
Progressive Myopia
MAD Trial: Myopia Atropine Dose
The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety…
- Trial name
- MAD (NCT05667454)
- Testing
- Atropine Ophthalmic 0.05%, Atropine Ophthalmic 0.5%
- Where
- 20 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Erasmus Medical Center
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia, Myopic Astigmatism
Machine Learning Prediction of 1-Year Refractive Error After SMILE
This retrospective single-center observational study is designed to develop and internally validate a multi-output machine learning model for predicting 1-year postoperative refractive prediction error after small incision…
- Conditions
- Myopia, Myopic Astigmatism, Refractive Error - Myopia Axial
- Trial name
- SMILE (NCT07478419)
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tongji University
Myopia
Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center
This randomized controlled trial aims to evaluate the efficacy and safety of low-dose topical atropine sulphate (0.05%), a non-selective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in…
- Trial name
- NCT07164092
- Testing
- Atropine 0.05% Eye drops
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Myopia, Orthokeratology
The Relationship of Relative Corneal Refractive Power Shift and Axial Length in Adolescents With Orthokeratology Lens
Orthokeratology lens is an effective method for myopia control. This study analyzed the relationship between the relative corneal refractive power shift and change of axial length in adolescents with orthokeratology lens.
- Trial name
- NCT05348369
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Tianjin Eye Hospital