Clinical trials: Refractive Errors
Myopia
Dietary Supplement for Myopia Control
The purpose of this clinical trial is to investigate the changes in choroidal thickness and vasculature in myopic children following oral supplementation.
- Trial name
- NCT07406906
- Testing
- Oral dietary supplement provided in a capsule format (3 active capsules/ per day)
- Where
- Hong Kong
- Volunteers
- 156 people
- Sponsor
- The Hong Kong Polytechnic University
Primary Open Angle Glaucoma, Myopia
Diagnostic Innovations in Glaucoma Study
The overarching goal of our research study is to evaluate changes in visual function and optic nerve topography (the structure of the back of the eye) in patients with glaucoma (increased susceptibility to pressure inside the eye…
- Trial name
- DIGS (NCT00221897)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Ametropia
Prospective Study Evaluating Dry Eye in Patients Operated on for Ametropia by LASIK Surgery and Treated With REPADROP
LASIK is a refractive surgery technique widely used in France. Postoperatively, the classic treatment after LASIK consists of instilling drops to reduce dry eyes.
- Trial name
- PREPADROP (NCT04654455)
- Testing
- Describe the evolution of dry eye between 1 month and 3 months post-LASIK
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Age Related Cataracts, Astigmatism
Femtosecond Laser-assisted Astigmatism Treatment
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure including arcuate incisions (AI) correcting astigmatism, also referred…
- Trial name
- FLAAT (NCT04321226)
- Testing
- Femtosecond Laser guided Arcuate Keratotomy
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Medical University of Vienna
Myopia, Myopic Astigmatism
Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
The objectives of this study are to evaluate the safety and efficacy of a treatment regimen for high myopia and myopic astigmatism: LASIK followed by crosslinking performed with the KXL Crosslinking-System and VibeX Xtra…
- Conditions
- Myopia, Myopic Astigmatism, Crosslinking, Corneal Ectasia
- Trial name
- NCT03913338
- Testing
- LasikXtra, LASIK
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Myopia
Corneal Endothelial Cell Injury Induced by Mitomycin-C
our study will investigate the effecacy of Mitomycin-C in TransEpi single step photorefractive keratectomy (PRK) and alcohol assisted PRK
- Trial name
- NCT05548478
- Testing
- Transepithelial PRK/MMC, Alcohol-Assisted PRK/MMC
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Myopia
In-vivo Wettability Grading and Assessment Study
The purpose of this study is to investigate the front surface wettability of soft contact lenses while on eye.
- Trial name
- CIAN (NCT01010555)
- Testing
- lotrafilcon B, balafilcon A, senofilcon A
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- CIBA VISION
Refractive Error
Evaluation of a Surgical Microscope Mounted Autorefractor When Used on Patients Lying in a Supine Position
The purpose of this study is to evaluate the accuracy and repeatability of an individually validated prototype autorefractor designed to be mounted on a surgical microscope.
- Trial name
- NCT01827748
- Testing
- Intraoperative Autorefractor IAR-1, Hartmann-Shack Auto Refractor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adventus Technology
Myopia, Myopia; Refractive Error
Efficacy and Visual Quality of Orthokeratology Lenses With Different Designs
Orthokeratology (ortho-k) lens is very effective in slowing down axial elongation in myopic children by 30% to 63% when compared to children wearing single-vision spectacles or contact lenses.
- Trial name
- NCT06825585
- Testing
- Orthokeratology with 5.0mm back optical zone diameter, Orthokeratology with a 6.2 mm back optical zone diameter
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Yang
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Hyperopia
Hyperopia Correction Using the NTK Optimal Keratoplasty (Opti-K) System
The purpose of this U.S. Clinical Trial on treatment of sighted eyes is to investigate the safety and effectiveness of optimal keratoplasty (Opti-K™) treatments for hyperopia correction using the NTK Enterprises (NTK) Opti-K…
- Trial name
- NCT01028937
- Testing
- Optimal Keratoplasty
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NTK Enterprises, Inc.
Presbyopia
Comparison of Two Soft Bifocal Contact Lenses
The purpose of the study is to compare the visual performance of two soft bifocal contact lenses.
- Trial name
- NCT00724945
- Testing
- balafilcon A, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 113 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Effects of Projected Peripheral Defocus on Ocular Biometrics
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04388020
- Testing
- Tabletop prototype of eSpecs: Active projection of defocused image in the peripheral visual field, Tabletop prototype of eSpecs: No Active projection of defocused image in the peripheral visual field
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Presbyopia Correction, Presbyopia
Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses
The purpose of the study is to assess participant experience when wearing multifocal contact lenses compared to spherical contact lenses with reading glasses.
- Trial name
- NCT07218731
- Testing
- Multifocal contact lenses, Spherical contact lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Myopia, Perfusion; Complications
OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes
Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation.
- Trial name
- NCT04424069
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Ametropia
Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A
This will be an up to six months, subject-masked, contralateral, parallel-group, randomised, daily wear study. All subjects will wear the Test lens in one eye and the Control lens in the other eye.
- Trial name
- NCT04525170
- Testing
- HPT treatment, untreated
- Where
- 2 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Contamac Ltd
Myopia, Astigmatism
Wavefront-guided Photorefractive Keratectomy (PRK) Versus Wavefront-guided Lasik for Myopia
A prospective comparison of eyes undergoing wavefront-guided LASIK in one eye and wavefront-guided PRK in their fellow eye for myopia.
- Trial name
- NCT01140594
- Testing
- Photorefractive keratectomy, Laser in-situ keratomileusis
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Pilot Study on the Adaptation and Tolerance of Essilor® Myopia-control Spectacle Lenses
This observational pilot study aims to evaluate the adaptation and tolerance of Essilor® Stellest® myopia-control spectacle lenses in children with progressive myopia.
- Trial name
- STELLAR (NCT07340931)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
Myopia
Myopia Progression and the Effect of 7-Methylxanthine
7-methylxanthine has been shown to increase the concentration and thickness of collagen fibrils in rabbit sclera. Deficient collagen in the sclera may be the cause of progression of childhood myopia.
- Trial name
- NCT00263471
- Testing
- 7-methylxanthine
- Volunteers
- 90 people
- Sponsor
- Trier Research Laboratories
Cataract With Pre-existing Regular Corneal Astigmatism
Influence of Implantation Technique on Rotational Stability of a Frosted-Haptic Toric Intraocular Lens: A Prospective Contralateral-Eye Study
This prospective, randomized contralateral-eye study evaluates whether the implantation technique influences the rotational stability and refractive outcomes of the TECNIS Eyhance™ Toric II intraocular lens (IOL) during cataract…
- Trial name
- NCT07768722
- Testing
- OVD-assisted Implantation, BSS-assisted hydroimplantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
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