Clinical trials: Refractive Errors
Cataract, Presbyopia
Evaluation of Visual Outcomes in Patients With Complex Corneas Implanted With the IC-8 IOL
The purpose of this study is to evaluate visual outcomes in patients with complex corneas who have been previously implanted with the IC-8 IOL after cataract removal.
- Conditions
- Cataract, Presbyopia, Irregular; Contour of Cornea
- Trial name
- NCT05377515
- Where
- Singapore
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia
Study of AGN-190584 Eye Drops to Assess Safety and Efficacy in Participants Aged 40-80 Years With Pseudophakic Presbyopia
Presbyopia is a condition in which the eye exhibits a diminished ability to focus on near objects with increasing age. This study will assess the safety and exploratory efficacy of AGN-190584 is in treating participants with…
- Trial name
- ARIES (NCT05393089)
- Testing
- AGN-190584, Vehicle
- Where
- 32 sites in United States
- Sponsor
- Allergan
Myopia
Projected Peripheral Defocus Using a Wearable Device
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04415684
- Testing
- Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.), No Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia
Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Evaluation of the efficacy in decreasing myopia progression of the proposed ophthalmic lens prototypes.
- Trial name
- NCT05250206
- Testing
- Myopia control lens
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens
Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed lens (control), when worn on a daily basis for 1 month.
- Trial name
- NCT03499067
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- CooperVision, Inc.
Ametropia
Safety and Efficacy of a New Transepithelial Photorefractive Keratectomy Treatment
This is a prospective, comparative, randomized, controlled, single-blind, single-surgeon, single-center PMCF clinical study whereby participants undergoing refractive surgery for correction of ametropia will receive a…
- Trial name
- NCT04698174
- Testing
- Transepithelial Photorefractive keratectomy (tPRK) without laser polishing, Transepithelial Photorefractive keratectomy (tPRK) with laser polishing, Standard Photorefractive keratectomy (PRK)
- Where
- Philippines
- Volunteers
- 39 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Evaluation of a Surgical Microscope Mounted Autorefractor When Used on Patients Lying in a Supine Position
The purpose of this study is to evaluate the accuracy and repeatability of an individually validated prototype autorefractor designed to be mounted on a surgical microscope.
- Trial name
- NCT01827748
- Testing
- Intraoperative Autorefractor IAR-1, Hartmann-Shack Auto Refractor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adventus Technology
Myopia; Astigmatism
Dispensing Evaluation of Investigational Contact Lenses
Non-randomized, single-masked, 2-visit, bilateral wear, single-arm dispensing study to evaluate the visual acuity, rotational performance, lens fit, stability and subjective characteristics of a senofilcon-based JJVCI…
- Trial name
- NCT02625220
- Testing
- Prototype toric lens senofilcon A
- Where
- 12 sites in United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Astigmatism
Safety and Effectiveness of Arcuate Incisions Performed With the iFS Femtosecond Laser System
To determine if arcuate incisions performed with the iFS femtosecond laser are safe and effective in reducing corneal astigmatism.
- Trial name
- NCT01348854
- Testing
- iFS Femtosecond Laser System
- Where
- 4 sites in Austria, France and 1 more
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Stable Myopic Refractive Error, With or Without Astigmatism
Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.
- Trial name
- NCT02675751
- Testing
- STAR S4 IR laser with iDesign
- Volunteers
- 167 people
- Sponsor
- Abbott Medical Optics
Myopia, Astigmatism
Product Performance of a Toric Contact Lens
Product performance of a Bausch \& Lomb Toric Contact Lens compared to Ciba Vision Focus Daily Toric Contact Lens
- Trial name
- NCT00658996
- Testing
- SofLens DD Toric, Ciba Vision Focus Dailies Toric Contact Lens
- Where
- Malaysia
- Volunteers
- 220 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Clinical Performance of Habitual Hydrogel vs. Silicone Hydrogel Toric Contact Lenses
Evaluate the clinical performance of existing wearers of hydrogel toric lenses when refitted with Avaira toric silicone hydrogel contact lenses over 1 week of wear.
- Trial name
- NCT02142361
- Testing
- enfilcon A
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.