Clinical trials: Refractive Errors
Presbyopia
Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design
The objective of the study was to adapt existing multifocal soft lens wearers to a CONTROL lens for 2 weeks and then evaluate the success of switching them to the TEST lens, with a review after 2 weeks.
- Trial name
- NCT04952701
- Testing
- Control lenses, Test lenses
- Where
- 5 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Performance of Existing Wearers of Enfilcon A Following a Refit With Fanfilcon A Lenses for 4 Weeks
The aim of this dispensing study is to evaluate the clinical performance of habitual wearers of enfilcon A lenses following a refit with fanfilcon A lenses over 4 weeks of daily wear.
- Trial name
- NCT02670473
- Testing
- fanfilcon A (test)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.
- Trial name
- NCT01362907
- Testing
- Delefilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
- Trial name
- NCT04980456
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 257 people
- Sponsor
- Alcon Research
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
- Trial name
- NCT05338333
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
- Where
- 8 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alcon Research
Myopia
Clinical Performance Comparison of Several Different Contact Lenses
The purpose of the study is to evaluate the possible benefits of second generation silicone hydrogel contact lenses.
- Trial name
- NCT00912028
- Testing
- senofilcon A, lotrafilcon B, balafilcon A
- Where
- 11 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses
The objective of the study was to compare the lens performance of two daily disposable multifocal contact lenses.
- Trial name
- NCT05763628
- Testing
- Control Lens (stenfilcon A), Test Lens (senofilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- CooperVision, Inc.
Myopia
Daytime Corneal Swelling During Wear of Narafilcon B Lenses
The purpose of this research is to measure daytime open-eye response to wearing of narafilcon B lenses.
- Trial name
- NCT01444287
- Testing
- narafilcon B, Polymacon, Lotrafilcon A
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error, Astigmatism
Visual Performance Investigation of Two Toric Soft Contact Lenses
The purpose of this study is to compare the amount of coma as measured by aberrometry induced by two silicone hydrogel toric lenses in astigmatic participants.
- Conditions
- Refractive Error, Astigmatism, Myopia, Hyperopia
- Trial name
- CARDINAL (NCT01858701)
- Testing
- Lotrafilcon B toric contact lens, Comfilcon A toric contact lens
- Volunteers
- 49 people
- Sponsor
- Alcon Research
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Stable Myopic Refractive Error, With or Without Astigmatism
Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.
- Trial name
- NCT02675751
- Testing
- STAR S4 IR laser with iDesign
- Volunteers
- 167 people
- Sponsor
- Abbott Medical Optics
Myopia
Comparison of Somofilcon A Daily Disposable Test Contact Lens and Somofilcon A Daily Disposable Control Contact Lens
The purpose of this study is to investigate the overall clinical performance of the somofilcon A daily disposable test soft contact lens compared to the somofilcon A daily disposable control soft contact lens.
- Trial name
- NCT03372551
- Testing
- somofilcon A 1 day test lens, somofilcon A 1 day control lens
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- CooperVision, Inc.
Myopia
A Clinical Assessment of the Hemacopolymer Daily Disposable Limbal Ring Soft Contact Lens
This purpose of this study is to compare the clinical performance and subjective acceptance of two different daily disposable limbal ring lenses.
- Trial name
- NCT01965262
- Testing
- Hema-copolymer Lens, etafilcon A Lens
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax
The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.
- Trial name
- NCT02987660
- Testing
- Topography Guided LASIK, Small Incision Lenticular Extraction, WaveLight EX500 Excimer Laser System
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Alcon, a Novartis Company
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05431543
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution
- Where
- 5 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Ametropia
The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses
This subject-masked, randomized, bilateral crossover study will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a…
- Trial name
- NCT04067141
- Testing
- somofilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Bifocal & Atropine in Myopia (BAM) Study
This study will test whether the combined treatment of 0.01% atropine and soft bifocal contact lens wear produces slower myopia progression and axial elongation compared to soft bifocal contact lenses alone in children ages 7 to…
- Trial name
- BAM (NCT03312257)
- Testing
- Multifocal D +2.50 add & 0.01% atropine
- Volunteers
- 49 people
- Sponsor
- Jenny Jones