Clinical trials: Refractive Errors
Hyperopia, Hyperopic Astigmatism
Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism
The objectives of this study are to evaluate the safety and efficacy, with regards to regression of refractive outcome, as measured by manifest refraction spherical equivalent (MRSE), of two treatment regimens for hyperopic and…
- Trial name
- NCT01893359
- Testing
- riboflavin ophthalmic solution, 0% dextran, UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA), UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off)
- Where
- 5 sites in United States
- Volunteers
- 2 people
- Sponsor
- Glaukos Corporation
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism
Small amounts of astigmatism are often uncorrected in contact lens wearers. The effect with respect to driving is unknown, but it could threaten safe operation of a motor vehicle, especially under conditions such as nighttime…
- Trial name
- NCT02624791
- Testing
- 1-DAY ACUVUE® MOIST contact lenses, 1-DAY ACUVUE® MOIST for ASTIGMATISM contact lenses, No contact lenses
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Myopia
Clinical Evaluation of Two Daily Wear Silicon Hydrogel Contact Lens
The purpose of this study is to demonstrate that the VISCO (Olifilcon A) soft contact lens could be prescribed as a supportive care for myopic persons.
- Trial name
- NCT02354924
- Testing
- Biofinity soft contact lens, Visco soft contact lens
- Volunteers
- 60 people
- Sponsor
- Visco Vision Inc.
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Astigmatism
Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions
To assess the effectiveness of the Verion-LenSx guided arcuate incision technique to reduce astigmatism in a pseudophakic population.
- Trial name
- NCT02763124
- Testing
- Verion-LenSx
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Gainesville Eye Associates
Myopia
Prospective Study of an Investigational Daily Disposable Contact Lens
The purpose of this study is to evaluate the performance of an investigational daily disposable contact lens.
- Trial name
- NCT01295905
- Testing
- delefilcon A contact lens, narafilcon B contact lens
- Volunteers
- 90 people
- Sponsor
- CIBA VISION
Cataract, Astigmatism
Patient Perception of Visual Distortions
The purpose of this study is to evaluate visual distortions reported by pseudophakic patients.
- Trial name
- NCT02203747
- Testing
- Administration of patient self-assessment
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Myopic Astigmatism
A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic Astigmatism
The primary objective of this study is to collect safety and effectiveness data for the Technolas Teneo 317 Model 2 excimer laser for LASIK correction in participants with myopia and myopic astigmatism.
- Trial name
- NCT04111757
- Testing
- Technolas® TENEO 317 Model 2
- Where
- 10 sites in United States
- Volunteers
- 168 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Myopia
Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens
The purpose of this study was to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.
- Trial name
- NCT06046209
- Testing
- Control Lens, Test Lens
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.