Clinical trials: Refractory Benign Strictures
Benign Airway Stenosis, Respiratory Tract Fistula
Clinical Study on Autologous Stromal Vascular Fraction(SVF) Treatment for Refractory Benign Airway Stenosis and Respiratory Tract Fistula
Benign airway stenosis and respiratory tract fistula are common types of airway injury. The diseases occurred after endogenous and exogenous stimuli (tuberculosis, tumor, surgery, tracheal intubation) causing damage to the airway…
- Trial name
- NCT05270850
- Testing
- Control group, SVF group
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Esophageal Dilation, Refractory Benign Esophageal Stricture
Outcomes of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management
This study is being done to see which treatment is more effective in improving the difficulty of swallowing. Researchers are comparing self-dilation to endoscopic dilation.
- Trial name
- NCT03738566
- Testing
- Esophageal self-dilation therapy, Endoscopic therapy with esophageal dilation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mayo Clinic
Refractory Benign Esophageal Strictures Caused by Caustic Ingestion
Esophageal Fully Covered Metal Stents in Caustic Strictures Study
The purpose of this study is to establish clinical proof of concept of temporary indwell of the WallFlex™ Esophageal Fully Covered Metal Stent (FCMS) for the treatment of refractory benign esophageal strictures caused by caustic…
- Trial name
- NCT01899300
- Testing
- Metal Stent (WallFlex™ Esophageal RX)
- Where
- 2 sites in India
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Benign Airway Stenosis
Clinical Study on Autologous Platelet-rich Plasma (PRP) Treatment for Refractory Benign Airway Stenosis
Platelet-rich plasma(PRP), is a concentrate of platelet-rich plasma protein derived from whole blood. The main components of it are platelets, leukocytes and fibrin.
- Trial name
- NCT03892837
- Testing
- PRP, Conventional treatment for benign airway stenosis
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Esophageal Stricture
The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children
To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.
- Trial name
- NCT04524897
- Testing
- Triamcinolone Injection in treatment of refractory benign Esophageal Stricture in children
- Volunteers
- 20 people
- Sponsor
- Assiut University
Refractory Benign Strictures
UAS-RBS: a Safety Study
A novel stent, called Universal Partially Covered Removable Self-expanding Stent and Anchoring System for the Treatment of Refractory Benign Esophageal Strictures (UAS-RBS) was designed to improve the treatment of benign…
- Trial name
- NCT03652285
- Testing
- Esophageal stent implantation, Stent removal
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- Erasme University Hospital
Pediatric Disorder, Esophageal Diseases
Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children
This clinical trial study included 21 children with refractory benign esophageal strictures. Upper GI endoscopy performed up to the area of stricture, esophageal dilatation done, endoscopy repeated, and steroid injected…
- Conditions
- Pediatric Disorder, Esophageal Diseases, Esophageal Stricture
- Trial name
- ISIs (NCT06514079)
- Testing
- Esophageal dilatation with steroids injection
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Mohammad Daboos
Refractory Benign Esophageal Strictures
Early Versus Late Endoscopic Stenting for Refractory Benign Esophageal Strictures
This project is being done to compare two current treatment clinical options for management of RBES: 1) Frequent dilations followed by temporary esophageal stent placement if dilations fail, or 2) Early stent placement followed…
- Trial name
- RBES (NCT06991049)
- Testing
- Fully covered self-expandable metal esophageal stent
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Refractory Anastomotic Esophageal Strictures
WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture
The purpose of this of this study is to compare the safety and effectiveness of temporary indwell of the WallFlex Esophageal FC Metal Stent to Bougie Dilation for the treatment of refractory anastomotic esophageal strictures
- Trial name
- E7025 (NCT01699542)
- Testing
- WallFlex Esophageal RX Fully Covered Stent, Esophageal Bougie Dilator Per Investigator preference
- Where
- 4 sites in Brazil, Netherlands and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Esophageal Stricture
Mitomycin-C Injection Therapy in Refractory Esophageal Stricture
Intralesional Mitomycin-C (MMC) injection has recently been introduced to resolve refractory benign esophageal stricture mostly in children.
- Trial name
- NCT04284826
- Testing
- Endoscopic injection of Mitomycin-C on bougie-dilated refractory benign esophageal stricture
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Ajou University School of Medicine