Clinical trials: Refractory Celiac Disease
Celiac Disease
Rifaximin for the Treatment of Persistent Symptoms in Patients With Celiac Disease
Celiac disease is a condition in which the small intestine is damaged by gluten, the storage protein of wheat and similar proteins in barley and rye.
- Trial name
- NCT01137955
- Testing
- Rifaximin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Celiac Disease
AMG 714 Expanded Access Program
Expanded access requests for AMG 714 may be considered for adult patients with biopsy proven Refractory Celiac Disease Type II who have failed all available treatment options and do not have EATL.
- Trial name
- NCT03439475
- Testing
- AMG 714
- Sponsor
- Amgen
Celiac Disease, Celiac Sprue
Antibody Treatment for Advanced Celiac Disease
Background: Celiac disease is a condition where the immune system attacks the cells of the small intestine. The intestine becomes inflamed and cannot digest food properly.
- Conditions
- Celiac Disease, Celiac Sprue, Gluten Enteropathy, Gluten-Sensitive Enteropathy
- Trial name
- NCT01893775
- Testing
- Hu-Mik- Beta-1
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Cancer Institute (NCI)
Celiac Disease, Small Bowel Disease
Histomolecular Profiling in Small-Bowel Diseases
This prospective cohort study aims to establish reliable histological reference values for normal small-bowel mucosa, improve histological diagnostic quality in celiac disease, and develop an advanced molecular profile for…
- Conditions
- Celiac Disease, Small Bowel Disease, Refractory Celiac Disease
- Trial name
- Deep Bowel (NCT07556328)
- Where
- 3 sites in Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Celiac Disease
Immune Response in Celiac Disease on In-vitro Gluten Challenge
The main purpose of this study is to see how cells taken from the lining of the intestine behave in the laboratory with exposure to gluten and other substances that act on the immune system.
- Trial name
- NCT01909050
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Beth Israel Deaconess Medical Center
Type II Refractory Celiac Disease (RCD-II), In-situ Small Bowel T-cell Lymphoma
Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease
Protocol CELIM-RCD-002 is designed to evaluate the efficacy and safety of AMG 714 for the treatment of adult patients with type II refractory celiac disease (RCD-II), an in-situ small bowel T-cell lymphoma.
- Trial name
- NCT02633020
- Testing
- AMG 714
- Where
- 6 sites in United States, Finland and 3 more
- Volunteers
- 28 people
- Sponsor
- Amgen
Celiac Disease
Impact of Gluten Contamination in Celiac Patients Clinically Responsive and Unresponsive to the Gluten-free Diet
The primary aim of the study is to detect the presence of gluten immunogenic peptides (GIP) in urine samples from celiac patients on a gluten-free diet clinically responsive and non-responsive to dietary treatment and from…
- Trial name
- GIP (NCT05066191)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Intractable Abdominal Pain Secondary to Inoperable Malignancy
EUS-guided CGN for Inoperable Cancer
Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours. Management of these patients would be towards palliation of symptoms.
- Trial name
- NCT02356640
- Testing
- EUS-guided celiac ganglion neurolysis, Percutaneous celiac plexus neurolysis, Olympus UM 2000
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Chinese University of Hong Kong
Celiac Disease
Comparison Between Axial- and Lateral-viewing Capsule Endoscopy in Celiac Disease
Video capsule endoscopy (VCE) is recommended as the gold standard in small bowel exploration. The efficiency of the axial-viewing (Given, Imaging) has been widely reported.
- Trial name
- NCT03095573
- Testing
- Lateral-viewing CapsoCam device, Axial-viewing capsule
- Where
- 2 sites in Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Celiac Plexus Block
Endoscopic Ultrasound Guided Versus Percutaneous Celiac Plexus Block in Patients With Intractable Upper Abdominal Pain
Upper abdominal pain is a common and often debilitating symptom in patients with pancreatic cancer and chronic pancreatitis, and is frequently under-treated by standard opioid therapy despite dose escalation and associated side…
- Trial name
- NCT07865286
- Testing
- Endoscopic Ultrasound-Guided Celiac Plexus Block, Percutaneous Celiac Plexus Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University