Clinical trials: Regional Anesthesia Block, open to volunteers
Local Anesthesia, Dental Implants
Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants
This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar…
- Conditions
- Local Anesthesia, Dental Implants, Periimplantitis
- Trial name
- NCT07590037
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Anesthesia, Local
Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches
This randomized, double-blinded volunteer study compares two ways of performing the adductor canal (AC) nerve block at the mid-thigh to see which approach more reliably numbs the anteromedial knee.
- Trial name
- NCT07444827
- Testing
- Traditional adductor canal block, NVM (nerve to vastus medialis) targeted adductor canal block, Chloroprocaine Injection
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS)
Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery
Effective postoperative pain management is essential after thoracic surgery. Insufficient pain control may impair breathing and coughing, increasing the risk of pulmonary complications such as collapsed lungs (atelectasis) or…
- Conditions
- Regional Anesthesia, Video-assisted Thoracoscopic Surgery (VATS), Erector Spinae Plane Block, Intercostal Nerve Block
- Trial name
- NCT07535697
- Testing
- Anesthesiological, Ultrasound-Guided "Erector Spine Plane Block" (ESPB), Surgical, Thoracoscopically-Guided "Intercostal Nerve Block" (ICNB)
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Anesthesia, Local
Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy
The aim of this study is to determine the effect of PENG blockade on postoperative pain after either ropivacaine 5 mg/mL or saline (placebo) in patients undergoing PAO.
- Trial name
- NCT06406010
- Testing
- Ropivacaine 5mg/ml 20ml, Saline 0.9%
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Matias Vested
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Obesity Postoperative Pain, Obesity Morbid Obesity Postoperative Pain
Comparison of Paragastric Nerve Block and Erector Spinae Plane Block on Postoperative Pain After Sleeve Gastrectomy
Background: Laparoscopic sleeve gastrectomy is one of the most commonly performed bariatric procedures for the treatment of obesity.
- Trial name
- PGB-ESP (NCT07811206)
- Testing
- Paragastric Nerve Block (PGNB), ESPB, Active Comparator
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Atlas University
Persistent Idiopathic Facial Pain (PIFP)
Deciphering Persistent Orofacial Pain - PIFP
Persistent non-dental orofacial pain is common yet poorly characterised, and its pathophysiology remains largely unknown. Two clinically similar entities are distinguished: post-traumatic trigeminal neuropathic pain (PTNP), in…
- Trial name
- NCT07791004
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC3 (NCT06974032)
- Testing
- Xylocaine jelly 2%, Surgilube
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Infraclavicular Brachial Plexus Block
Pulse Wave Transit Time After Infraclavicular Block
This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block.
- Trial name
- NCT07669688
- Testing
- Ultrasound-guided infraclavicular brachial plexus block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC (NCT06960317)
- Testing
- Buffered Lidocaine, Unbuffered lidocaine, Xylocaine jelly 2%
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
Respiratory Depression
Effect of Propofol Versus Remimazolam Intravenous Anesthesia on Respiratory Depression
General anesthesia is the preferred choice for pediatric patients, but the induction of volatile anesthetics via face mask may cause preoperative anxiety and postoperative delirium.
- Trial name
- NCT06816173
- Testing
- Propofol group, Remimazolam group
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Anesthesia, Analgesia
Near Remote Method to Guide Performance of Regional Anesthesia
Ultrasound-guided regional anesthesia/analgesia techniques (or simply, 'regional blocks') have gained popularity as they can reduce, and sometimes even eliminate, the need for opiate analgesics (and, consequently, their side…
- Conditions
- Anesthesia, Analgesia, Nerve Block, Delivery of Healthcare
- Trial name
- NCT05968261
- Testing
- Real time 'near remote' guidance of regional blocks
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Regional Anesthesia Morbidity, Supratentorial Brain Tumor
Ketamine Versus Dexmedetomidine as an Adjuvant in Scalp Block in Supratentorial Brain Tumor Excision Surgeries
Supratentorial brain tumor surgeries are associated with significant nociceptive stimulation and postoperative pain, which may adversely affect patient outcomes.
- Conditions
- Regional Anesthesia Morbidity, Supratentorial Brain Tumor, Acute Pain
- Trial name
- NCT07698665
- Testing
- Scalp Block with Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Regional Anesthesia
Comparing Postoperative Analgesic Techniques for Umbilical Hernia Repair: A Randomized Trial of Ultrasound Guided Caudal, Erector Spinae, and External Oblique Interfascial Plane Blocks
The aim of this study is to evaluate the efficacy of ultrasound guided Erector block versus caudal block versus external oblique intercostal plane block perioperatively
- Trial name
- NCT06948253
- Testing
- Erector Spinae Plane Block, Caudal Block Anesthesia, External Oblique Intercostal Plane Block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University