Clinical trials: Regional Block
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Head-Down Tilt Following Spinal Anesthesia
Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgeries. Several factors determine the spread of local anaesthetic solutions in CSF.
- Trial name
- NCT03491319
- Testing
- Group X - head low tilt, Group Y - head low tilt, Group C - neutral
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nitte University
Healthy, Nerve Block
Phase I Study of Ropivacaine, Clonidine, and Betamethasone Combination for Sciatic Nerve Block in the Popliteal Region
This is a national, single-center, dose-escalation Phase I study to investigate the safety, pharmacokinetics, and efficacy of a combination containing Ropivacaine, Clonidine, and Betamethasone (Ropiclobet) in healty volunteers.
- Trial name
- RopiCloBet (NCT06781632)
- Testing
- ropivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- PHARMAFINA
In-plane Ultrasound-guided Regional Anesthesia Performance
Trial on the Effects of Ultrasound Probe Position on Ultrasound-guided Nerve Blocks
Ultrasound has been used to guide a needle to inject local anesthetics around nerves. This is usually done in the same plane as the ultrasound beam in America and is known as an in-plane technique.
- Trial name
- NCT01690156
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Surgery, Acute Pain
IPACK and Adductor Canal Catheter Patient Outcomes for TKAs?
This study evaluates the addition of the IPACK block to the adductor canal block and catheter in the pain management of total knee arthroplasty.
- Trial name
- NCT03774966
- Testing
- Adductor Canal Block + Catheter & IPACK block, Adductor canal block + catheter
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hand Surgery
Ulnar Nerve Block for Procedural Anesthesia - Wrist Versus Palm
Ulnar nerve blockade is necessary for sensory anesthesia and analgesia in the hand during minor procedures. The course of the ulnar nerve in the forearm, wrist, and hand is predictable and has low variability.
- Trial name
- NCT00827658
- Testing
- Volar Wrist Block, Hypothenar Palm block
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Postoperative Pain Management, Open-heart Surgery
Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery
This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median…
- Conditions
- Postoperative Pain Management, Open-heart Surgery, Median Sternotomy, Erector Spinae Plane Block
- Trial name
- ESPB-SYSHEART (NCT07259057)
- Testing
- Erector spinae plane block (ESPB), Intravenous Opioid Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Healthy
The Effect of Different Doses (Mass) of Local Anesthetic on Duration of Adductor Canal Block in Healthy Volunteers - Part 2
To investigate whether increased dose of local anesthetic (lidocaine) increases duration of peripheral nerve block (adductor canal block) and to develop a model for assessing duration of peripheral nerve blockades.
- Trial name
- NCT02172729
- Testing
- Adductor canal block with 20 ml lidocaine, single bolus
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anesthesia, Local
Comparison of The Effectiveness of Intraligamentary and Mandibular Anesthesia on Mandibular Molar Teeth
This study aimed to compare the effects of mandibular and intraligamentary anesthesia techniques on pain scores during restorative treatment of permanent mandibular molars in pediatric patients.
- Trial name
- NCT05115773
- Testing
- Intraligamentary anaesthesia, Mandibular anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Pain, Postoperative
Continuous Erector Spinae Block Versus Continuous Paravertebral Block
Overall Aim: To evaluate the efficacy of continuous erector spinae block (ESB) versus continuous paravertebral block (PVB) for postoperative analgesia in children and adolescents undergoing surgical procedures via unilateral…
- Trial name
- NCT03768440
- Testing
- continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Tooth Extraction Status Nos, Anesthesia, Local
Efficacy and Safety of Administration of Different Doses of 4% Articaine.
The goal of this triple-blind randomized clinical trial is to compare the efficacy and safety of administering one cartridge (1.8 mL) versus two cartridges of articaine 4% with epinephrine 1:100,000 for lower third molar…
- Trial name
- NCT06644950
- Testing
- Efficacy and safety of administering 1 or two cartridges of anesthesia
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Opioid Use
Laparoscopic Assisted Plane Block (LAPB) Trial
This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks.
- Trial name
- NCT03730402
- Testing
- Bupivacaine, Exparel 266 milligram Per 20 ML Injection, Saline
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Santa Barbara Cottage Hospital
Orchiectomy, Spermatic Cord Block
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate…
- Conditions
- Orchiectomy, Spermatic Cord Block, Spinal Anesthesia, Pain Score
- Trial name
- NCT06313775
- Testing
- bilateral orchiectomy
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
MRI Scanner Configuration
The Axillary Region in a High Resolution MRI
The axillary region is regularly used for brachial plexus block. The technique may be guided by nerve stimulation, ultrasound or a combination of nerve stimulation and ultrasound.
- Trial name
- NCT01442857
- Testing
- MRI
- Where
- Norway
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine