Clinical trials: Regression
Contrast Induced Nephropathy
Effect of Sodium Bicarbonate Solution in Decreasing the Incidence of Contrast Induced Nephropathy (CIN)
Radio Contrast Induced Nephropathy (RCIN) remains a well recognized complication in patients undergoing diagnostic or interventional procedures requiring radiographic contrast agents.
- Trial name
- NCT00514150
- Testing
- Sodium Bicarbonate plus normal saline 0.9%, normal saline 0.9%
- Where
- Iran
- Volunteers
- 265 people
- Sponsor
- Tehran University of Medical Sciences
Chronic Migraine, Migraine Disorders
Osteopathic Manipulative Treatment and Migraine Headaches
In this study the investigators hypothesize, that Osteopathic Manipulative Therapy (OMT) will reduce migraine disability and severity scores when compared to standard of care including prophylactic pharmacological agents with…
- Conditions
- Chronic Migraine, Migraine Disorders, Headache Disorders, Headache, Migraine
- Trial name
- NCT04976985
- Testing
- Osteopathic Manipulative Therapy (OMT), Standard of care
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Delirium
Decreasing Delirium Through Music
DDM is a study designed to Test the efficacy of personalized music therapy in reducing delirium incidence and severity among patients admitted to the Intensive Care Unit.
- Trial name
- DDM (NCT03095443)
- Testing
- Music Therapy - Personalized Playlist, Music Therapy - Standard Playlist, Attention Control
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Indiana University
Carcinoma, Non-Small-Cell Lung
The Effect on Decreasing Chemotherapeutic Toxicity and Increasing Anti-tumor Effect of Chinese Herbs Based on Syndrome Differentiation
To study the effect on decreasing chemotherapeutic toxicity and increasing anti-tumor treatment of Chinese Herbs based on syndrome differentiation
- Trial name
- NCT02737735
- Testing
- standard chemotherapy medicine combined with Chinese herbs, standard chemotherapy medicine
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Acne Vulgaris
Decreasing Severity of Acne Vulgaris After the Use of a Combination of Anti-Acne Cream
This study was conducted to see whether there was a decrease in the degree of acne vulgaris / pimple, to find out what proportion of respondents experienced a decrease in severity and who did not experience a decrease in the…
- Trial name
- NCT04118296
- Testing
- Anti-Acne Preparations for Topical Use
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Sukma Skin Treatment
Breast Cancer
Pre-operative Exercise During Neoadjuvant Chemotherapy in Patients With Breast Cancer
The Neo-Train study is a randomized controlled trial investigating the effects of supervised pre-operative aerobic and resistance exercise in patients with breast cancer during neoadjuvant chemotherapy.
- Trial name
- Neo-train (NCT04623554)
- Testing
- Prehabilitation program
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Zealand University Hospital
Dental Caries Extending Into Dentine
Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth
The objective of this study was to analyze the radiographic density of digital subtraction radiographs after SMART restoration with partial caries removal in primary molars at 6 and 12 months.
- Trial name
- DSR (NCT01749267)
- Testing
- partial caries removal only at enamel dentin junction.
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Androgenetic Alopecia
Efficacy Study of a Cosmetic Lotion in the Treatment of Androgenetic Alopecia in Males and Females
The purpose of this study is to determine whether the Hair Loss Prevention Lotion named MEXIS, M.P.A.F., M6S PATENT is effective in the treatment of Androgenetic Alopecia.
- Trial name
- MEXISPATENT (NCT01701271)
- Testing
- Hair loss prevention lotion
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mexis George
Wounds and Injuries, Adolescent
Implementing a School Prevention Program to Reduce Injuries Through Neuromuscular Training
The purpose of this study is to evaluate the effectiveness of a neuromuscular training program in decreasing sport and recreational injuries and improving healthy outcomes in junior high school students (grades 7 to 9).
- Conditions
- Wounds and Injuries, Adolescent, Athletic Injuries, Sport Injury
- Trial name
- iSPRINT (NCT03312504)
- Testing
- Neuromuscular training program, Standard-of-practice Warm-up (Control)
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- Sport Injury Prevention Research Centre
Essential Hypertension, Carotid Plaque
The Confirmatory Olmesartan Plaque Regression Study
Effect of olmesartan medoxomil (20-40 mg) on plaque regression in hypertensive patients with carotid atherosclerosis.
- Trial name
- CONFIRM (NCT01132768)
- Testing
- Atenolol, olmesartan medoxomil
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Postoperative Pain
Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain
There is an increasing trend on decreasing narcotic use and maximizing efficiency in the perioperative care. There are no studies that have compared a TAP block versus a TAP block plus gabapentin for laparoscopic procures.This…
- Trial name
- NCT02927405
- Testing
- Gabapentin, TAP Block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
Pain
Using Dexamethasone After Uvulopalatopharyngoplasty
This study looks at lessening the pain after a Uvulopalatopharyngoplasty (UPPP) surgery by using Dexamethasone (a corticosteroid).
- Trial name
- NCT00584168
- Testing
- Dexamethasone
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Low-Moderate Hypercholesterolemia
Clinical Trial to Demonstrate the Efficacy of a Dietary Supplement in Decreasing Cardiovascular Risk
This clinical trial seeks to verify the efficacy of a red rice yeast dietary supplement in the decrease of cardiovascular risk, by assessing variables related with cardiovascular risk as levels of cholesterol, triglycerides and…
- Trial name
- NCT03828006
- Testing
- Red Rice Yeast
- Where
- 3 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Bioksan
Cellulitis, Insect Bites
Point-of-Care Ultrasound Educational Initiative for Insect Bites
This pre-post study, designed to decrease unnecessary antibiotic prescribing, will use a prospective cohort of patients presenting to the Pediatric Emergency Department (PED).
- Conditions
- Cellulitis, Insect Bites, Insect Stings
- Trial name
- USED4BUGBITE (NCT03619746)
- Testing
- POCUS Educational Intervention
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- New York City Health and Hospitals Corporation
Behavioral Health
Multi-Site Feasibility Testing a Meditation App for Youth in the Legal System
This multi-site feasibility clinical trial aims to assess the feasibility of implementing a 1-month app-based meditation program with youth in 4 heterogeneous juvenile legal systems across Oregon and New York.
- Trial name
- NCT07674303
- Testing
- Bodhi AIM, HIB
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cancer Cervix Uterus, Precancerous Lesions
The Effect of Physical Activity and Abstain From Smoking on the Precancerous Lesion
In this proposed project,investigators will estimate the effect of physical activity and abstain from smoking on the regression of precancerous neoplasia.
- Conditions
- Cancer Cervix Uterus, Precancerous Lesions, Smoking
- Trial name
- NCT03093623
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 446 people
- Sponsor
- Taipei Medical University
Autosomal Dominant Polycystic Kidney Disease, Nephrogenic Diabetes Insipidus
Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration
The purpose of this research is to study the effectiveness and safety of the medication PB in slowing the frequent urination related to tolvaptan as long-term treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD), or…
- Conditions
- Autosomal Dominant Polycystic Kidney Disease, Nephrogenic Diabetes Insipidus, Acquired Nephrogenic Diabetes Insipidus, Congenital Nephrogenic Diabetes Insipidus
- Trial name
- SerendipityPB1 (NCT05190744)
- Testing
- PB
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia
Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults
This study is a randomized controlled trial. It is estimated that 80 quitters will be recruited, and they will be randomly included in the experimental group and 40 in the control group.
- Trial name
- NCT04679636
- Testing
- heart rate variability biofeedback
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Defense Medical Center, Taiwan
Pseudoexfoliation Glaucoma, Primary Open-angle Glaucoma
Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma
This study aims to evaluate the effect of a single session of micropulse laser trabeculoplasty (MLT) on cornea in eyes with primary open glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG).
- Trial name
- NCT03483402
- Testing
- Micropulse laser trabeculoplasty
- Volunteers
- 27 people
- Sponsor
- University Hospital of Patras
Peripheral Arterial Disease, Atherosclerosis
Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With PAD and Claudication
The purpose of this trial is to evaluate the safety and efficacy of sonodynamic therapy (SDT) on reducing atherosclerotic plaques inflammation among patients with symptomatic femoropopliteal peripheral artery disease.
- Conditions
- Peripheral Arterial Disease, Atherosclerosis, Cardiovascular Diseases
- Trial name
- SMART-PAD (NCT03457662)
- Testing
- OMC and pseudo-SDT, OMC and SDT
- Where
- China
- Volunteers
- 32 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University