Clinical trials: Regression
Hematologic Malignancy
Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation
The LLLT has an anti-inflammatory, analgesic effect and accelerates the healing of ulcerated lesions. There are little data in the literature showing its efficacy in prevention of mucositis in cohorts of patients with…
- Trial name
- STOP MUCITES (NCT02696408)
- Testing
- Laser treatment
- Where
- 3 sites in France
- Volunteers
- 234 people
- Sponsor
- Institut de Cancérologie de la Loire
Atherosclerosis
Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is a promising tool for identifying and quantifying vascular inflammation within atherosclerotic plaques.
- Trial name
- NCT00926055
- Testing
- Ezetrol (Ezetimibe), Vytorin (Ezetimibe + Simvastatin)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University
Malignant Neoplasm, Psychosocial Effects of Cancer and Its Treatment
Psycho-Educational Program in Increasing Knowledge and Satisfaction and Decreasing Distress in Younger Patients With Cancer Receiving Treatment
This pilot clinical trial studies psycho-educational program in increasing knowledge and satisfaction and decreasing distress in younger patients with cancer receiving treatment.
- Trial name
- NCT01817335
- Testing
- psychosocial assessment and care, educational intervention, communication skills training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- City of Hope Medical Center
Sedentary Lifestyle
An Experimental Study on Music and Sedentariness Among Mothers and Children
The aims of the study: Main objective of the current study is to decrease sedentary behavior and increase physical activity among mothers and their offspring by using music-to-movement video program.
- Trial name
- MovingSound (NCT02270138)
- Testing
- Movement-to-music video program
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- UKK Institute
No Evidence of Disease
Celecoxib in Decreasing the Damaging Effects of Sunburn in Healthy Volunteers
This clinical trial studies celecoxib in decreasing the damaging effects of sunburn in healthy volunteers. Celecoxib may reduce skin damage by blocking enzymes associated with sunburn in healthy volunteers.
- Trial name
- NCT02090933
- Testing
- Celecoxib, Laboratory Biomarker Analysis, UV Light Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
ACL Injury
Effectiveness of a Novel Warm-up in Decreasing Risk Factors for ACL Injury in Female Youth Soccer Players
There is a large number of young women who sustain serious knee injuries from playing soccer. Female athletes are at high risk of knee injuries from soccer than males.
- Trial name
- NCT01591941
- Testing
- Core-PAC
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
High Blood Sugar, Metabolic Syndrome
Effect of ANKASCIN 568-P Products on Decreasing HbA1c and Regulating Blood Glucose
This study is a randomized, double-blind, placebo-controlled, parallel-controlled trial (24 weeks in total), divided into three periods (screening, treatment, and discontinuation follow-up)
- Trial name
- NCT05737342
- Testing
- ANKASCIN 568-P Red yeast rice capsules
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- SunWay Biotech Co., LTD.
Hypertension, Blood Pressure
The Effect of Household-based Screening on Blood Pressure Changes in South Africa
This study will evaluate the effect of household-based screening and care encouragement for blood pressure on subsequent changes in blood pressure.
- Trial name
- NCT03762304
- Testing
- Household blood pressure screening with care encouragement
- Volunteers
- 3,986 people
- Sponsor
- Till Bärnighausen
Disc Disease
The Effectiveness of Lumber Regression Technique on Disc Bulge Randomized Control Trial
Lumbar disc bulges lead to considerable pain and disability in affected individuals, with current interventions lacking consistency of outcomes. The lumbar regression method offered a hopeful, noninvasive option.
- Trial name
- NCT06548334
- Testing
- Advanced Physiotherapy, Conventional Physiotherapy Techniques
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Superior University
Chronic Total Occlusion, Anxiety
Decreasing Patient Anxiety During Revascularization of Chronic Total Coronary Occlusions Using Virtual Reality Glasses.
Percutaneous coronary angioplasty on chronic total occlusions is a complex procedure. The possibility of performing these procedures without anesthesia and sedation avoids the risks associated with anesthesia and sedation, but…
- Trial name
- ReViCTO (NCT05458999)
- Testing
- Virtual reality headset during percutaneous coronary intervention
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Preterm Birth, Low Birth Weight
Diagnostic Accuracy of Foot Length in Predicting Preterm and Low Birth Weight Using Ultrasound Dating as The Gold Standard in a Rural District of Pakistan
Background: The burden of preterm and low birth weight babies (LBW) is high in low- and middle-income countries (LMICs). Therefore, assessment of gestational age (GA) and birth weight is important.
- Trial name
- NCT05515211
- Testing
- Foot length
- Where
- Pakistan
- Volunteers
- 336 people
- Sponsor
- Aga Khan University
Surgical Procedure, Unspecified
Decreasing Emergence Agitation With Personalized Music
The purpose of the study is to assess the impact of personalized music on emergence agitation (EA), as measured by Pediatric Anesthesia Emergence Delirium scores in pediatric patients recovering from elective procedures under…
- Trial name
- NCT05044832
- Testing
- Personalized Music
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Resistant Hypertension
Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Trial From RENEWAL RDN Registry)
1. (RENEWAL-EXERCISE trial) The investigators hypothesize that the increased sympathetic nervous system activation that is associated with resistant hypertension is a major contributor in the pathogenesis of exercise diastolic…
- Trial name
- NCT01918111
- Testing
- Renal denervation, adenosine infusion treatment
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Yonsei University
Carotid Artery Disease
CARotid plaqUe StabilizatiOn and Regression With Evolocumab.
The CARUSO trial aims at investigating the efficacy of evolocumab in promoting carotid plaque morphological stabilization and regression as compared to traditional lipid lowering therapy (LLT).
- Trial name
- CARUSO (NCT04730973)
- Testing
- Evolocumab, lipid-lowering therapy (LLT)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliera Ordine Mauriziano di Torino
HIV Infections, Lipodystrophy
A Study of Increased Lactic Acid and Abnormal Fat Distribution in HIV-Positive Patients
The purpose of this study is to see if the findings of increased lactic acid and abnormal fat distribution get better when d4T is replaced with abacavir, abacavir plus lamivudine, or Combivir (a pill containing lamivudine plus…
- Trial name
- NCT00005764
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate, Lamivudine
- Where
- 31 sites in United States
- Volunteers
- 100 people
- Sponsor
- Glaxo Wellcome
Depression, Postpartum, Malnutrition, Child
Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) for Improved Nutrition Outcomes
The project seeks to test the integration of Interpersonal Psychotherapy for Groups within Care Group projects and investigate whether the treatment of maternal depression with Interpersonal Psychotherapy for Groups improves the…
- Trial name
- NCT03573713
- Testing
- Care Groups, IPT-G
- Where
- Uganda
- Volunteers
- 1,248 people
- Sponsor
- Food for the Hungry
Hypertrophy, Left Ventricular
The CLEVER Study - Coreg And Left Ventricular Mass Regression
This study is designed to compare the effects of COREG MR (carvedilol modified release formulation) to atenolol on indices of left ventricular dimensions when added to standardized angiotensin converting enzyme (ACE) inhibition…
- Trial name
- NCT00108082
- Testing
- carvedilol MR, atenolol, lisinopril
- Where
- 78 sites in United States
- Volunteers
- 287 people
- Sponsor
- GlaxoSmithKline
Allergy, Peanut
Efficacy and Safety of QGE031 (Ligelizumab) in Patients With Peanut Allergy
This was a 52-week, Phase 3 multi-center, randomized, double-blind and placebo-controlled study to assess the safety and clinical efficacy of two dosing regimens of ligelizumab (240 mg and 120 mg) SC q4w (subcutaneous injection…
- Trial name
- NCT04984876
- Testing
- ligelizumab
- Where
- 55 sites in United States, Australia and 8 more
- Volunteers
- 211 people
- Sponsor
- Novartis Pharmaceuticals
Blood Loss, Surgical, Intrapartum Hemorrhage
Efficacy of Carbetocin Versus Oxytocin Plus Misoprostol in Decreasing Blood Loss During Cesarean Section
The aim of this clinical trial is to test if carbetocin is as effective as oxytocin plus misoprostol in decreasing intraoperative blood loss in women undergoing planned cesarean section.
- Trial name
- NCT05664659
- Testing
- Oxytocin + misoprostol, Carbetocin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams Maternity Hospital