Clinical trials: Regression
Atrial Fibrillation, Atrial Flutter
Decreasing Hospital Admissions From the ED for AAFF
Acute atrial fibrillation and flutter (AAFF) is characterized by rapid heart rates with onset less than seven days. It's the most common type of palpitation treated in the Emergency Department (ED).
- Trial name
- RAFF-3 (NCT03627143)
- Testing
- KTI activities
- Where
- 12 sites in Canada
- Volunteers
- 846 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Esophageal Squamous Cell Carcinoma
Standardized MRI and Structured Reporting for Esophageal Squamous Cell Carcinoma
This prospective, multicenter diagnostic accuracy study will develop and validate a standardized 3.0-T magnetic resonance imaging (MRI) acquisition protocol and structured reporting system for primary esophageal squamous cell…
- Trial name
- ESCC-MRI-TRG (NCT07769658)
- Testing
- Standardized 3.0-T Esophageal Magnetic Resonance Imaging
- Where
- 7 sites in China
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Prediction Hypothyroidism Patients Using Machine Learning Algorithms, Identification of Important Symptoms of Hypothyroidism
Identification of Important Symptoms and Diagnostic Hypothyroidism Patients Using Machine Learning Algorithms
Hypothyroidism (HT) is one of the most common endocrine diseases. It is, however, usually challenging for physicians to diagnose due to non-specific symptoms. The usual procedure for diagnosis of HT is a blood test.
- Trial name
- NCT06112886
- Testing
- There was no intervention in this study
- Where
- Iran
- Volunteers
- 1,296 people, healthy volunteers welcome
- Sponsor
- Kerman University of Medical Sciences
Pancreatectomy
Improving Mental and Physical Health and Decreasing Hospital Readmission After Pancreatectomy Through Enhanced Patient and Caregiver Education and Engagement
The study of readmission is in its infancy in the surgical world, and there are no prospective studies, to the investigators' knowledge, evaluating the efficacy of interventions on preventing readmission following pancreatectomy.
- Trial name
- NCT02617979
- Testing
- SAFECARE at Home customized lessons
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Washington University School of Medicine
Overactive Bladder
Virtual Reality (VR) During Peripheral Nerve Evaluation (PNE) Procedure
The purpose of this research is to evaluate whether or not wearing a virtual reality headset affects pain and anxiety in patients undergoing percutaneous nerve evaluation (PNE).
- Trial name
- NCT05928910
- Testing
- SmileyScope VR, Standard of Care Treatment
- Sponsor
- University of Miami
Melanoma, Meningioma
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Background: The National Cancer Institute (NCI) Surgery Branch has developed an experimental therapy for treating patients with cancer that involves taking white blood cells from the patient, growing them in the laboratory in…
- Conditions
- Melanoma, Meningioma, Breast Cancer, Non-Small Cell Lung Cancer
- Trial name
- NCT01967823
- Testing
- Anti-NY ESO-1 mTCR PBL, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
Posttraumatic Stress Disorder, Depression
Decreasing Youth Involvement in Violence in Burundi
The purpose of the current study is to examine the psychological well-being of youth within the context of participation in political violence during the 2015 election period in Burundi.
- Conditions
- Posttraumatic Stress Disorder, Depression, Aggression
- Trial name
- NCT02503488
- Testing
- Narrative Exposure Therapy for Forensic Offender Rehab, Treatment as Usual
- Where
- Burundi
- Volunteers
- 40 people
- Sponsor
- University of Konstanz
Orthodontic Tooth Movement
Effectiveness of Olive Oil Local Application in Orthodontic Patients.
The large body of evidence supports the chemotherapeutic potential of substances found in Olive Oil (OO), acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation.
- Trial name
- NCT05040620
- Testing
- Olive Oil Topical Oil
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Minia University
Diabetes Mellitus Type 2, Metabolic Syndrome
Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients of South Asian Descent
Among South Asians, in comparison to Western Europeans, there is an increased risk of type 2 diabetes mellitus (DM2) and DM2-related cardiovascular disease.
- Conditions
- Diabetes Mellitus Type 2, Metabolic Syndrome, Cardiovascular Disease, Diastolic Dysfunction
- Trial name
- MAGNA VICTORIA (NCT02660047)
- Testing
- Liraglutide
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Leiden University Medical Center
HIV-1 Infection
Pilot Peg-Interferon-a2b in Decreasing Viral DNA in HIV
We propose to test our primary hypothesis that treatment with Peg-IFN-α-2b will result in a decrease in integrated HIV DNA in peripheral blood and tissue in chronically HIV-infected immune-reconstituted individuals (see section…
- Trial name
- NCT01935089
- Testing
- Pegylated Interferon alpha 2b
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- The Wistar Institute
Myopic Regression
Effect of Timolol on Refractive Outcomes in Eyes With Myopic Regression After LASIK: a Randomized Clinical Trial
In this randomized controlled clinical trial, we compare the effects of timolol versus placebo for treatment of myopic regression after LASIK
- Trial name
- NCT01506635
- Testing
- Timolol
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Postoperative Pain
Decreasing Postoperative Pain Following Endometrial Ablation
To determine whether paracervical injection of long acting local anesthesia decreases postoperative pain following endometrial ablation under general anesthesia.
- Trial name
- NCT02660918
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Pain
Using Dexamethasone After Uvulopalatopharyngoplasty
This study looks at lessening the pain after a Uvulopalatopharyngoplasty (UPPP) surgery by using Dexamethasone (a corticosteroid).
- Trial name
- NCT00584168
- Testing
- Dexamethasone
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Aging, Skin Abnormalities
Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers
With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effects of UVA, a type of…
- Trial name
- NCT00520910
- Testing
- Polypodium leucotomos
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Exercise Promotion
An Examination of the Efficacy of a Self-Determination Theory and Motivational Interviewing Exercise Intervention
The current study involves conducting an intervention based on self-determination theory (SDT) and motivational interviewing (MI) to promote physical activity in a racially-diverse sample.
- Trial name
- NCT02250950
- Testing
- MI and SDT Exercise Group, Non-MI and SDT Exercise Group
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Hypofibrinogenemia, Afibrinogenemia
Human Fibrinogen Concentrate in Pediatric Cardiac Surgery
The goal of the study is to determine whether the use of Human Fibrinogen Concentrate (RiaSTAP) will decrease blood loss and the need for component blood therapy in neonates and infants undergoing cardiopulmonary bypass.
- Conditions
- Hypofibrinogenemia, Afibrinogenemia, Bleeding Disorders
- Trial name
- RiaSTAP (NCT02822599)
- Testing
- RiaStAP, Saline
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Disorders of Sexual Development
Disorders of Sexual Development and Gonadal Tumor Risk
Disorders of Sexual Development are rare and represent a spectrum of heterogeneous pathologies. The risk of developing a malignant gonadal germ cell tumor (MGCT) exists and varies according to the etiology.
- Trial name
- DEV-GEN-RiTuGo (NCT06682078)
- Testing
- Not applicable . Non-interventional retrospective study, only on datas.
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Loneliness, Social Isolation
Decreasing Loneliness in Older Adults
The purposes of this study are: (1) decrease loneliness and social isolation and increase social competence and social integration of older adults experiencing loneliness; (2) examine an intervention process grounded in a…
- Trial name
- I-SOCIAL (NCT01842984)
- Testing
- I-SOCIAL intervention
- Where
- Israel
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Myopia
Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Evaluation of the efficacy in decreasing myopia progression of the proposed ophthalmic lens prototypes.
- Trial name
- NCT05250206
- Testing
- Myopia control lens
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Proliferative Diabetic Retinopathy
Evaluation of Treatment of High riSk proLiferative Diabetic retinopathY With Intravitreal Aflibercept injectioN
To assess the safety and efficacy of intravitreal aflibercept injection in the regression of retinal neovascularization secondary to high-risk PDR.
- Trial name
- ELYSIAN (NCT02630277)
- Testing
- Aflibercept
- Volunteers
- 30 people
- Sponsor
- Valley Retina Institute