Clinical trials: Regulation of Acute Inflammatory Response
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Endothelial Dysfunction, Regulation of Acute Inflammatory Response
Endothelial Dysfunction and Selenium Status in Children With Acute Systemic Inflammatory Response
The overall hypotheses of this project is that severe sepsis is associated with endothelial dysfunction in pediatric patients and that selenium deficiency is associated with changes in biological markers of endothelial…
- Conditions
- Endothelial Dysfunction, Regulation of Acute Inflammatory Response, Selenium Deficiency
- Trial name
- NCT02619344
- Where
- Brazil
- Volunteers
- 114 people
- Sponsor
- Federal University of São Paulo
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Acute Pancreatitis
Continuous Blood Purification for Regulation of Early Inflammatory Response In Severe Acute Pancreatitis
Systemic Inflammatory response syndrome(SIRS) is common in patients with severe acute pancreatitis (SAP) in early stage. Continuous Blood Purification (CBP), especially Continuous Veno-Venous Hemofiltration(CVVH) is proved to…
- Trial name
- NCT01998334
- Testing
- CVVH 6h, CVVH 10h, CVVHDF 6h
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital