Clinical trials: Rehabilitation, completed
Hypertension
Understanding the Exercise-Hypertension Paradox
Hypertension affects 37% of the Veteran population, making it the most common medical condition treated by the VA Health Care System. Physical activity is the first line of defense in the treatment and management of hypertension.
- Trial name
- NCT02034422
- Testing
- Oral Antioxidant, Exercise rehabilitation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries
Effects of Robotic Versus Manually-Assisted Locomotor Training for Individuals With Incomplete Spinal Cord Injury
The purpose of this study is to collect data comparing two means of providing locomotor training: manual and robotic and the possible differential effects it may have on walking ability for persons with spinal cord injury (SCI).
- Trial name
- DE (NCT00127439)
- Testing
- Manually Assisted Locomotor Training, Robotic Assisted Locomotor Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Total Knee Arthroplasty, Osteoarthritis
Optimizing Physical Activity Outcomes After Total Knee Arthroplasty
Although total knee arthroplasty is an effective intervention for decreasing knee pain and improving physical function, physical activity levels remain low up to a year after surgery.
- Trial name
- NCT03226106
- Testing
- Physical Activity Behavior Intervention, Attention Control
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- VA Office of Research and Development
Vestibular Diseases
Computerized Vestibular Rehabilitation
Disorders of vestibular function and balance are an important component of many conditions that commonly affect veterans, such as inner ear diseases, diabetes, and traumatic brain injury.
- Trial name
- NCT03589859
- Testing
- VOR Test, Computer Game, Nausea Scale
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Rehabilitation of the Stroke Hand at Home
The purpose of this research is to evaluate a therapy delivery system for stroke patients that provide accessible, affordable stroke care.
- Trial name
- HAAPI (NCT01144715)
- Testing
- Hand Mentor (TM) robotic stroke therapy device, Home Therapy Program
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Kinetic Muscles
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
Self-Administered Interactive Exercise Program (Tele-Exergame)
This longitudinal Phase I feasibility trial combines care-as-usual with a 6-week, single-arm exercise intervention using Tele-Exergame, an interactive, self-administered home-based exercise program aimed at improving…
- Conditions
- Mild Cognitive Impairment (MCI), Mild Alzheimer Disease, Memory Deficits
- Trial name
- NCT07072962
- Testing
- home-based self-administered interactive exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
Stroke, Physical Disability
Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.
- Trial name
- NCT04569123
- Testing
- real stimulation, No stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Medical University of South Carolina
Stroke, Weakness, Muscle
EMG Training for Altering Activation Patterns After Stroke
Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.
- Conditions
- Stroke, Weakness, Muscle, Coordination Lack
- Trial name
- NCT03619772
- Testing
- Bilateral, Unilateral
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Moral Injury
Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans
The need for moral injury interventions is increasingly being recognized as a domain in Veteran care that must be addressed. Consequences of exposure to morally injurious events include risk for suicide, substance abuse, and…
- Trial name
- NCT03760731
- Testing
- Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Neoplasms
Yoga Cancer Rehabilitation Study: A Randomized Trial of Adaptive Yoga for Older Cancer Survivors
With advances in the detection and treatment of cancer, there are now 14 million cancer survivors in the U.S., 500,000 of whom are treated in the Veterans Health Administration.
- Trial name
- YogaCares (NCT01324102)
- Testing
- Yoga therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- VA Office of Research and Development
Retinitis Pigmentosa
Computer-Assisted Rehabilitation Environment Training After Argus Retinal Prosthesis
The goal of the current project is to fill the unmet clinical needs around the objective assessment of visual function and develop outcome-oriented visual rehabilitation approach using the computer assisted rehabilitation…
- Trial name
- NCT03444961
- Testing
- CAREN system training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The Cleveland Clinic
Multiple Sclerosis, Gait Disorders, Neurologic
Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple Sclerosis
The investigator plans to test the use of the Ekso Bionics® Gait Training (Ekso GT™) exoskeleton for gait training in MS patients. The device will solely be used in the clinic under direct supervision from a physical therapist.
- Trial name
- NCT04000373
- Testing
- Ekso GT™ exoskeleton
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Cleveland Clinic
Retinal Dystrophies, Healthy
Optical Head-Mounted Display Technology for Low Vision Rehabilitation
The goal of this study is to examine the ability of optical head-mounted display technology to enlarge the visual field of patients with severe visual field loss due to retinal dystrophy and to improve mobility and…
- Trial name
- NCT02983305
- Testing
- Head-Mounted Display
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Homelessness, Mental Health Conditions
ASPIRE Cognitive Enhancement Study
Cognitive impairments are present in up to 80% of homeless individuals, and may contribute to homelessness in Operation Enduring Freedom / Operation Iraqi Freedom / Operation New Dawn (OEF/OIF/OND) Veterans.
- Trial name
- ACES (NCT02657954)
- Testing
- CCT, HCE
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- VA Office of Research and Development
Cerebrovascular Accident
Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke
This study will evaluate the effectiveness of treatment with acetylcholinesterase inhibitors in improving cognitive function and overall rehabilitation in elderly stroke survivors.
- Trial name
- NCT00227994
- Testing
- Galantamine, Donepezil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Stroke, Rehabilitation
Rehabilitation Robotic System ReHand
The aim of this clinical trial is to investigate the efficacy of the ReHand rehabilitation system for the recovery of patients after a stroke. The main objectives of the study: 1.
- Conditions
- Stroke, Rehabilitation, Robotic Exoskeleton
- Trial name
- NCT06937346
- Testing
- The Rehand Robotic Glove, Standard Rehabilitation
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Karaganda Medical University
Low Back Pain
Translation of Robotic Apparel for Alleviating Low Back Pain
This is a NIAMS-sponsored clinical trial being conducted through the NIH Helping to End Addition Long-term (HEAL) Initiative's Back Pain Consortium (BACPAC) Research Program.
- Trial name
- NCT05736393
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston University Charles River Campus
Stroke
Robot-Assisted Hand Motor Therapy for Subjects With Hemiparetic Stroke
The purpose of this study is to develop and assess the effectiveness of robot-assisted movement therapy in enhancing hand motor function in subjects with chronic hemiparetic stroke, and to identify predictors of treatment…
- Trial name
- Robot3 (NCT01244243)
- Testing
- Hand & Wrist Assisting Robotic Device
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Irvine
Ischemic Stroke
Efficacy and Safety of Mexidol® in Stroke Therapy
The main purpose of the clinical trial is to evaluate the efficacy and safety of Mexidol® in sequential treatment for patients in the acute and early recovery periods of ischemic stroke compared to placebo.
- Trial name
- MIR (NCT06437626)
- Testing
- Mexidol (Ethylmethylhydroxypyridine Succinate)
- Where
- 17 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 304 people
- Sponsor
- Pharmasoft
Stroke
Treatment of Chronic Stroke With IpsiHand
The ultimate goal of this project is to develop a functioning and clinically feasible method for restoring function to motor-impaired stroke survivors. This ultimate goal will be approached through two different means.
- Trial name
- NCT02552368
- Testing
- IpsiHand Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine