Clinical trials: Rejection
Kidney Transplant Rejection
Assessing AlloSure Dd-cfDNA Monitoring Insights of Renal Allografts With Longitudinal Surveillance
Prospective Observational Multicenter Cohort. External validation of donor derived cell free DNA in Renal Transplantation. Assessing performance of dd-cfDNA as a surveillance tool and its association with clinical outcomes.
- Trial name
- ADMIRAL (NCT04566055)
- Testing
- AlloSure
- Where
- 8 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CareDx
Pancreatitis, Graft, Pancreatic Transplant Post-Transplant Dysfunction Rejection
18F-Fluciclovine PET/CT in the Assessment of Pancreatic Transplants
Hypothesis 1: 18F-Fluciclovine PET/CT can correctly and easily identify the pancreatic allograft and determine its viability Aim 1: Assess whether 18F-Fluciclovine can identify the pancreatic allograft accurately and assess its…
- Trial name
- NCT04852523
- Testing
- 18F-fluciclovine
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Utah
Heart Transplant Rejection
Biomarkers for Diagnosis, Prognosis, and Targeted Therapy After Heart Transplantation
The objective of this prospective observational single center study is to investigate donor-derived cell-free DNA (ddcfDNA), peripheral blood platelet mRNA, peripheral blood extracellular vesicle mRNA, and peripheral blood…
- Trial name
- EMBIO (NCT06064123)
- Testing
- Cell-free DNA
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Life Change Events, Loneliness
Me and the Others: Expectations and Evaluation of Social Relationships
Chronic and pervasive loneliness has been identified as an important factor in the relationship between adverse childhood experiences (ACE) (e.g. abuse and neglect) and mental disorders.
- Trial name
- NCT03764566
- Testing
- Questionnaires
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim