Clinical trials: Rejuvenation
Problem of Aging
A Slit Face Trial Using Micro-injections of Transparent Hyaluronic Acid Gel for Rejuvenation of the Cheek
Soft tissue augmentation with injectable hyaluronic acid (HA) is a well-established modality for the correction of facial volume loss, fat atrophy, fine lines, and wrinkles.
- Trial name
- NCT02679924
- Testing
- Hyaluronic Acid filler
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Isabella Guiha
Wrinkle, Spot Pigmented
Skin Rejuvenation With Topical Extract and Other Nutraceuticals
Hemp extract has been shown in several pre-clinical and clinical studies to have anti-aging effects on the skin through anti-oxidant and anti-inflammatory effects, in addition resveratrol, thyme and caffeine have been shown to…
- Conditions
- Wrinkle, Spot Pigmented, Lines Skin
- Trial name
- NCT05734703
- Testing
- Nutraceutical Topical
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Microbiome, Immune Function
The RAMP Study - Rejuvenation of the Aging Microbiota With Prebiotics
An individual's immune and metabolic status is coupled to consumed carbohydrates. Complex carbohydrates that are not digested by human enzymes may influence host biology by impacting microbiota composition and function, or act in…
- Conditions
- Microbiome, Immune Function, Inflammation
- Trial name
- RAMP (NCT03690999)
- Testing
- Prebiotic supplement
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Stanford University
Aging, Botulinum Toxin
The Impact of Age on Botulinum Toxin Potency in Facial Rhytides Treatment
Botulinum toxin is approved by the FDA for the treatment of facial wrinkles. Patients are usually older than 45 years and their main demand is to treat pre-existing facial wrinkles.
- Conditions
- Aging, Botulinum Toxin, Facial Wrinkles
- Trial name
- NCT03836638
- Testing
- 30 Units of botulinum toxin, 50 Units of botulinum toxin
- Where
- Lebanon
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Rejuvenation
Energy Devices for Rejuvenation
Non-ablative and ablative devices are the most commonly used minimally-invasive treatments for skin rejuvenation. Current devices on the market for rejuvenation include the lasers such as the Fraxel Restore, the Halo, the Helios…
- Trial name
- NCT03767972
- Testing
- Energy-based device
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Perimenopausal Disorder, Menopause
Inovium Ovarian Rejuvenation Trials
The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause…
- Conditions
- Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions
- Trial name
- NCT03178695
- Testing
- Autologous PRP injection into human ovarian tissue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascendance Biomedical
Skin Pigment, Photoaging
A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation
The purpose of this investigation is to evaluate the safety and efficacy of the Cutera excel V Laser Genesis procedure utilizing the 1064nm laser for skin rejuvenation.
- Trial name
- NCT03421691
- Testing
- excel V Laser
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Wrinkle
Clinical and Histological Evaluation of BTL-785F Non-invasive Treatment for Facial Rejuvenation
This study will evaluate the clinical efficacy, safety and the performance of the BTL-785-2 applicator of the BTL-785F system for non-invasive treatment of facial wrinkles and correcting facial skin laxity.
- Trial name
- NCT05987917
- Testing
- BTL-785-2, No Treatment
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Aging
Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments
A non-randomized, evaluator-blinded study was conducted to observe the changes in the face before and after facial rejuvenation using microfocused ultrasound.
- Trial name
- NCT06286384
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Alopecia
Fractional Photothermolysis for Hair Follicle Induction
This study is being done to evaluate the effects of fractional photothermolysis (known as laser resurfacing) using fractional laser for the induction of hair follicles via skin rejuvenation in subjects with scalp alopecia…
- Trial name
- NCT03382184
- Testing
- Fraxel Dual laser, Halo laser
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Dysmorphic Disorder (BDD), Congenital Labia Majora Hypotrophy
To Assess The Performance And Tolerance Of Janesse 20 In The Volume Restoration Of Labia Majora
The use of hyaluronic acid (HA)-based fillers administered by injection to obtain Labia Majora augmentation is performed by many surgeons and gynaecologists in Europe, US and other countries, but few studies have investigated the…
- Conditions
- Dysmorphic Disorder (BDD), Congenital Labia Majora Hypotrophy, Post-menopausal Labia Majora Hypotrophy
- Trial name
- NCT04936763
- Testing
- Janesse 20 (Cross-linked Hyaluronic Acid)
- Where
- 2 sites in Italy, Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Ultrasound, Injection Site
Sonography-Guided Volumetric Rejuvenation on Dorsal Hands
The goal of this randomized controlled study is to guide volumetric rejuvenation on dorsal hands with the maximal aesthetic appearance.
- Trial name
- NCT05819450
- Testing
- Volumetric rejuvenation
- Where
- 2 sites in Spain, Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Aesthetic Procedures, Cosmetic Techniques
MENA Consensus on Poly-L-Lactic Acid (PLLA) Biostimulator Use in Aesthetic Dermatology
This study aims to develop expert consensus on the safe and effective use of poly-L-lactic acid (PLLA) biostimulators in aesthetic dermatology across the Middle East and North Africa (MENA) region.
- Conditions
- Aesthetic Procedures, Cosmetic Techniques, Skin Aging, Rejuvenation
- Trial name
- NCT07261748
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Research Center
Aesthetic
PLLA and CaHA-R for Aesthetic Rejuvenation
Skin ageing is intricately linked to collagen degradation caused by internal and external factors. External factors contributing to ageing include ultraviolet rays, smoking, heat, and air pollution, and follow a distribution…
- Trial name
- NCT07202117
- Testing
- Sculptra Aesthetic, Radiesse
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Skin Rejuvenation, Lipofilling
Effect of Adipose Derived Stem Cells on Survival of Fat as Filler
this research is to study the effect of Adipose Derived Stem Cells on Survival of Fat as Filler
- Trial name
- NCT03965936
- Testing
- lipofilling, lipofilling enriched with adipose tissue derived stem cells
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Skin Aging, Facial Aging
Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality
This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis.
- Conditions
- Skin Aging, Facial Aging, Skin Quality
- Trial name
- NCT07466953
- Testing
- Mesenchymal Stem Cell-Derived Exosome
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mert Ersan
Wrinkle
Micro-injections of Transparent Hyaluronic Acid Gel (Restylane® Silk) for Rejuvenation of the Aging Cheek
The objective of this study is to determine the efficacy and safety of Restylane® Silk microinjections when used in a grid-like injection pattern for the correction of fine lines to the cheeks.
- Trial name
- NCT03461198
- Testing
- Restylane® Silk
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
This randomized, single-center, double-blinded, controlled, clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after radiofrequency microneedling and…
- Trial name
- NCT06157853
- Testing
- Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Aging
Investigation of a Novel Cosmeceutical to Reduce the Visible Signs of Cutaneous Aging
Tomorrowlabs has developed a revolutionary cosmeceutical formulation to rejuvenate aging skin. Tomorrowlabs is conducting this research to study whether this cosmeceutical can reduce the visible signs of cutaneous aging.
- Trial name
- REDUCEAGE (NCT02877758)
- Testing
- Tomorrowlabs cosmeceutical formulation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tomorrowlabs GmbH
Aesthetics
Study to Evaluate Restylane Vital Light Using an Injector Device
The purpose of the study is to evaluate the safety and efficacy of Restylane Vital White administered with an injector device on aged skin in the face, hands and décolletage.
- Trial name
- NCT01412190
- Testing
- Restylane Vital Light, No treatment
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D