Clinical trials: Rejuvenation
Laser, Periorbital
Efficacy of Periorbital Rejuvenation With a 1927 nm Diode Laser Treatment
The purpose of this research project is to investigate the treatment design, therapeutic effects and safety of the 1927 nm laser for the rejuvenation of the skin around the eyes.
- Trial name
- NCT05811026
- Testing
- Periorbital rejuvenation with a 1927 nm diode laser treatment (2-week interval), Periorbital rejuvenation with a 1927 nm diode laser treatment (4-week interval)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Glabellar Lines, Midface Volume Deficiency
Prospective, Non-interventional Study Assessing Periorbital Rejuvenation Procedure
The goal of this observation is to assess the time course of holistic extended periorbital rejuvenation using botulinum toxin A, cross-linked hyaluronic acid and polynucleotides corresponding to the application in routine…
- Conditions
- Glabellar Lines, Midface Volume Deficiency, Periorbital Wrinkling
- Trial name
- NCT07398755
- Testing
- Letybo®, Philart® Eye, Saypha® Volume Plus Lidocaine
- Where
- Austria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yuvell
Skin Quality, Skin Wrinkles
Evaluation of Effects on Skin Quality of a Centella Asiatica Extracellular Vesicle-based Skin Care Formulation.
The study evaluates the effects of a skin care formulation containing Centella asiatica extracellular vesicles as the main active ingredient on facial appearance and skin quality in healthy participants.
- Conditions
- Skin Quality, Skin Wrinkles, Melanin Hyperpigmentation, Skin Hydration
- Trial name
- NCT06850935
- Testing
- Centella asiatica extracellular vesicle formulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Skin Manifestations, Wrinkle
A 56-day Clinical Study on Facial Skin Rejuvenation
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation…
- Conditions
- Skin Manifestations, Wrinkle, Photoaging
- Trial name
- NCT06188338
- Testing
- Fractional picosecond laser treatment followed by daily use of formulations containing MLYAAT-1002®., Fractional picosecond laser treatment followed by daily use of formulations without MLYAAT-1002®
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Laser Therapy, Exosomes
Enhancing Skin Rejuvenation Using Laser and Exosomes
Enhancing Skin Rejuvenation A Single-Blind, Randomized Control Study on the Combined Efficacy of Aerolase 1064 nm YAG Laser and Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells
- Trial name
- NCT07281690
- Testing
- 1064-nm Nd:YAG Laser Treatment, Topical Umbilical Cord-Derived Exosomes (UC-MSC Exosomes)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laser Beamer Skincare
Tear Trough Hollowing, Under Eye Bags
Platelet Rich Fibrin for Tear Trough Rejuvenation
The purpose of this study is to investigate the efficacy and longevity of Platelet Rich Fibrin (PRF) in combination with hyaluronic acid filler for cosmetic volume restoration of the tear troughs.
- Trial name
- NCT03313934
- Testing
- Hyaluronic Acid Filler and Platelet Rich Fibrin (PRF), Hyaluronic Acid Filler and Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rejuva Medical Aesthetics
Rejuvenation
The Efficacy of the Alma Hybrid System for a New Approach of Facial Skin Treatment
The study is aimed to evaluate the efficacy of the Alma Hybrid system for a new approach of facial skin treatment, using both ablative and non-ablative wavelengths.
- Trial name
- NCT04640207
- Testing
- Facial skin treatment
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
This randomized, multi-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after hybrid-fractional…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06436261
- Testing
- Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Laxity
Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing
The primary objective of this study is to evaluate the efficacy and tolerability of Pavise Extracellular Matrix Restore (ECMR), compared with standard acute post-operative care, when used as the primary occlusive treatment…
- Trial name
- NCT07462533
- Testing
- Pavise Serum, Co2/Er:YAG
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Skin Texture
Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation
The purpose of this study is to evaluate whether microneedling RF subcutaneous fat pad thickness in the temple, submental, and cheek regions, to determine whether the addition of topical PLLA after microneedling RF alters or…
- Trial name
- NCT07261527
- Testing
- microneedling RF treatment, PLLA, Sterile Water as control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Vulvar Atrophy
Evaluation of the Safety and Efficacy of Hyaluronic Acid Injection in Labia Majora Augmentation
The goal of this interventional clinical investigation using Genefill Contour® CE marked device outside of its indication is to compare with other hyaluronic acid device already marketed for labia majora augmentation in women…
- Trial name
- NCT06333782
- Testing
- Experimental- Genefill Contour®, Marketed comparator - Desirial®Plus
- Where
- 3 sites in France, Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bioscience Cosmetics SL
Wrinkle, Facial Expression
Comparison of the Effects of Two Frequencies of Application of Photobiomodulation on Facial Rejuvenation
Skin aging is an irreversible, slow and progressive process, being influenced mainly by age, but also by external factors such as ultraviolet radiation, smoking, alcohol, among others.
- Trial name
- NCT04911140
- Testing
- Photobiomodulation twice a week, Photobiomodulation three times a week, Simulated Photobiomodulation
- Where
- Brazil
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pre-cancerous Geriatric Skin
Effect of Dermal Rejuvenation on the UVB Response of Geriatric Skin
The objective of this study is to examine the ability of dermal rejuvenation therapies to protect geriatric skin from ultraviolet light (UVB)-induced carcinogenesis.
- Trial name
- Laser Genesis (NCT02090894)
- Testing
- UV Light (Laser Genesis)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Skin Aging, Skin Wrinklings
Facial Cosmetic Acupuncture on Skin Rejuvenation
Facial Cosmetic Acupuncture technique includes wrinkles, acupoints and muscle points on the face, head and neck. This study is designed to determine the efficacy and safety of Facial Cosmetic Acupuncture on skin rejuvenation.
- Trial name
- NCT01486303
- Testing
- Facial Cosmetic Acupuncture
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kyunghee University
Wrinkle
Association of Photobiomodulation With Platelet Rich Plasma Intradermal Injection for Facial Rejuvenation
Skin aging is an irreversible, slow and progressive process. It is influenced mainly by age, but also by external factors such as ultraviolet radiation, smoking, alcohol, among others.
- Trial name
- NCT04145999
- Testing
- PRP application, Photobiomodulation
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Blood Donors
Evaluation of Whole Blood With CPD Anticoagulant and AS-7/SOLX Additive Solution
This study will evaluate a new blood collection and filtration system that is intended to be used to collect, filter, separate and store red blood cells and, separately, plasma.
- Trial name
- NCT02145507
- Testing
- SOLX (Investigational), AS-3 (Control)
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation
Photoaging, Lentigo
TCA 15% Chemical Peel for Improvement in Hand Lentigines
This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter.
- Trial name
- NCT05471947
- Testing
- 15% Trichloroacetic acid + 3% glycolic acid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Aesthetic, Menopause
Post-Menopause Skin Rejuvenation Study
The post-menopausal state is marked by a sharp decline in estrogen, leading to significant structural and functional changes in the skin, including collagen loss, dryness, thinning, and reduced elasticity.
- Conditions
- Aesthetic, Menopause, Post-menopause, Injectables
- Trial name
- NCT07205744
- Testing
- Restylane SkinBoosters Vital, Sculptra Aesthetic
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Photodamaged Skin
Long-Pulsed Dye Laser and Intense Pulsed Light for Skin Rejuvenation.
The purpose of the trial is to compare clinical efficacy and occurrence of side effects in the treatment of photodamaged skin with Pulsed Dye Laser and Intense Pulsed Light.
- Trial name
- NCT00375141
- Testing
- Pulsed dye laser, Intense pulsed light
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital