Clinical trials: Rejuvenation
Facial Skin Hydration, Skin Rejuvenation
Comparison of KIRA Hydrating Treatment and Jet Peel for Facial Skin Hydration
This study compared the effects and tolerability of two non-invasive facial treatment systems on skin hydration: a hydroabrasion-jet system (KIRA) and a conventional high-pressure jet system (JET PEEL).
- Trial name
- NCT07793149
- Testing
- Vacuum-Assisted Hydroabrasion, High-Pressure Jet Infusion, Jet Infusion at 5 Bar
- Where
- 2 sites in Serbia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Faculty of Pharmacy Novi Sad
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Skin Aging of Face and Hands
A Pilot Study on the Use of Platelet Rich Plasma (PRP) for Facial and Hand Skin Rejuvenation
The overall goal of this study is to develop regenerative cell therapy for use in female patients with aging skin. The primary objective of this proposal is to conduct a pilot study on the efficacy and safety of using PRP to…
- Trial name
- PRP (NCT03647917)
- Testing
- Platelet Rich Plasma
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Skin Rejuvenation
Skin Rejuvenation Using Stem Cell Secretome
This clinical trial aims to investigate the effect of umbilical cord explants (UC)-explants and UC-mesenchymal stem cells (MSCs) secretome on skin rejuvenation, to provide future reference or standard in the application of cell…
- Trial name
- NCT06217627
- Testing
- secretome
- Where
- Lebanon
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- COR clinic of Regenerative Medicine
Wrinkle
Efficacy and Safety of 675-nm Laser for Dorsal Hand Rejuvenation
This study aimed to evaluate efficacy and safety of 675-nm laser for dorsal hand rejuvenation in Thai patients. Twenty-six subjects aged 50 to 65 years diagnosed with wrinkle and solar lentigines on both dorsums of hands were…
- Trial name
- NCT06486727
- Testing
- Redtouch
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Aging
Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks
This study tests whether certain medicines and a skin treatment can slow down or partly reverse the body's aging process. As people age, the activity of their genes changes in predictable ways.
- Trial name
- NCT07888595
- Testing
- Topical anti-aging peptide serum
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Frontiers in Bioscience Research Institute and Aging
Skin Laxity, Skin Tightening
Effects of QUANTUM Probe for Skin Rejuvenation and Subdermal Retraction in Patients Undergoing High-Definition Liposculpture
This prospective study aims to evaluate the safety and effectiveness of Quantum, a fully internal bipolar radiofrequency probe, for the treatment of prominent skin laxity, providing patients with a more toned and youthful…
- Conditions
- Skin Laxity, Skin Tightening, Body Contouring Surgery, Skin Elasticity
- Trial name
- Quantum001 (NCT06958978)
- Testing
- Quantum RF
- Where
- Colombia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Vascular Lesions, Photoaging
VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation
This is a multi-center, multi-cohort, prospective, open-label study of VELOS for treatment of vascular skin disorders. The plan is to enroll up to 60 subjects from up to 3 centers in the US and worldwide.
- Trial name
- NCT02468453
- Testing
- velos
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Facial Aging, Rejuvenation
Secretome Treatment for Facial Rejuvenation
Secretome treatment for facial rejuvenation
- Conditions
- Facial Aging, Rejuvenation, Stem Cell, Stem Cell Banking
- Trial name
- NCT07227883
- Testing
- Autologous Hair Follicle-Derived Secretome, Control Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acorn Biolabs Inc.
Skin Smoothness, Radiance
Clinical Case Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment on Healthy Females with Fitzpatrick Skin Types V and VI
This single-center, open-label, clinical case trial was conducted to evaluate the efficacy and tolerability of a topical facial treatment when applied by a license esthetician in clinic in a series of 3 sessions with 1 month…
- Conditions
- Skin Smoothness, Radiance, Overall Appearance
- Trial name
- NCT06633731
- Testing
- Biocellulose Mask, Post Procedure Cream, Gentle Cleanser
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Laser Therapy, Rejuvenation
Evaluation of Non-ablative and Fractional Combination Treatment for Improvement in Skin's Appearance
The study is designed to determine the safety, efficacy, patient comfort and patient satisfaction of the combined treatment of Refirme ST and Matrix RF both devices approved under 510k clearances.
- Trial name
- NCT01403597
- Testing
- Refirme ST Applicator and Matrix RF Applicator
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Aging
RESTOR: PK/PD mTORi Inhibition in Older Adults
As people get older, there are changes in their cells and tissues that may affect their ability to function. This can lead to increased death and age-associated disorders, like heart disease, cancer, and Alzheimer's disease.
- Trial name
- RESTOR (NCT06658093)
- Testing
- Rapamycin, Everolimus
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Fine Lines, Wrinkles
A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation
This single-center clinical trial was conducted to evaluate the efficacy and tolerability of a topical facial treatment when applied by a license esthetician in clinic in a series of 3 sessions with 1 month intervals, in…
- Conditions
- Fine Lines, Wrinkles, Laxity; Skin
- Trial name
- NCT06629792
- Testing
- Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging
Effectiveness and Safety of Cellbooster Shape in Healthy Subjects
SUISSELLE has developed a CE marketed (2021) HA-based superficial epidermis/dermis injection filler and skinbooster product, Cellbooster® Shape (CBS). CBS is produced using patented CHAC Technology.
- Trial name
- NCT07636512
- Testing
- Skin booster injection (CBS)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Suisselle
Infraorbital Hollows
Rejuvenation of the Lower Eyelid Using a Combination of Two Hyaluronic Acid Fillers - a Pilot Study
The primary objective of this study is to determine the efficacy and longevity of the use of Restylane® and Perlane® in combination for the rejuvenation of the infraorbital hollows and to measure patient satisfaction with this…
- Trial name
- NCT00852241
- Testing
- Restalyne, Perlane
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic