Clinical trials: Relapse to Smoking
Nicotine Dependence, Smoking Cue Reactivity
Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers
This trial aims to determine whether dopamine D3 receptors are elevated in smokers versus nonsmokers and whether correlations exist between D3 receptor binding potential (BP) and functional MRI (fMRI) reactivity to smoking cues…
- Conditions
- Nicotine Dependence, Smoking Cue Reactivity, Relapse to Smoking
- Trial name
- NCT01784016
- Testing
- [11C]-PHNO
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Smoking Cessation
Effectiveness of Mobile Phone-Based Intervention to Prevent Smoking Relapse Among Recent Smoking Quitters
Main Objective The main objective of the study is to investigate the effectiveness of a mobile phone-based intervention in reducing relapse ate among recent quitters who are attending the smoking cessation program in Jazan.
- Trial name
- NCT03994445
- Testing
- Mobile Phone-Based Intervention
- Where
- Saudi Arabia
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- Ibtihal Altalhi
Smoking Cessation
Technology-Enhanced Quitline Services to Prevent Smoking Relapse
The purpose of this study is to see if automated telephone monitoring will enhance existing quitline services, such as Alere Wellbeing's Quit For Life program, and help people quit smoking.
- Trial name
- TEQ (NCT00888992)
- Testing
- Quitline Service + 10 automated monitoring calls, Quitline service + 20 automated monitoring calls
- Where
- United States
- Volunteers
- 1,785 people, healthy volunteers welcome
- Sponsor
- Indiana University
PTSD, Smoking
Use of Technological Advances to Prevent Smoking Relapse Among Smokers With PTSD
The primary goal of the study is to evaluate the use of a new smart phone application in preventing relapse to smoking among people with PTSD.
- Trial name
- QUIT4EVER (NCT01990079)
- Testing
- Bupropion, nicotine replacement therapy, Smoking cessation counseling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Smoking, Low Physical Activity Level
Perfect Fit: Evaluation of a Virtual Coach for Smoking Cessation and Physical Activity
The leading cause of disease burden across the globe is cardiovascular disease (CVD). Important modifiable behavioral CVD risk factors include, amongst others, smoking and low physical activity (PA).
- Trial name
- NCT06095999
- Testing
- Perfect Fit intervention: virtual coaching intervention to quit smoking and increase physical activity
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Tobacco-Related Carcinoma
Episodic Future Thinking and Future Thinking Priming for Smoking Cessation
This trial studies the main and interactive effects of episodic future thinking and future thinking priming tasks on helping participants to quit smoking.
- Trial name
- NCT04297332
- Testing
- Behavioral Intervention, Informational Intervention, Nicotine Replacement
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Tobacco Use Disorder
Text Message Support to Prevent Smoking Relapse
The purpose of this research is to test a text message intervention for people who are beginning an attempt to quit smoking. The intervention seeks to teach people to think about their cravings to smoke in more helpful ways.
- Trial name
- NCT02968095
- Testing
- Text Message Craving Program, Self-Help Manual Plus Control Texts
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Miami University
Smoking Behavior, Smoking Lapse Behavior
Efficacy and Safety of NicVAX® Co-administered With Varenicline (Champix®)
The purpose of this study is to evaluate the efficacy and safety of NicVAX co-administered with varenicline as an aid in smoking cessation over a one-year period in smokers who want to quit smoking.
- Conditions
- Smoking Behavior, Smoking Lapse Behavior, Smoking Relapse Behavior
- Trial name
- NCT00995033
- Testing
- NicVAX vaccine, Varenicline
- Where
- 2 sites in Netherlands
- Volunteers
- 558 people
- Sponsor
- Maastricht University Medical Center
Smoking, Smoking Cessation
Biopsychosocial Predictors of Nicotine Relapse
This study aims to investigate the associations between emotion regulation ability, stress-induced neural activity changes, and susceptibility to relapse in smokers attempting to quit.
- Conditions
- Smoking, Smoking Cessation, Nicotine Addiction, Tobacco Smoking Behavior
- Trial name
- BioNic (NCT06470321)
- Testing
- Flexiquit Computerized Smoking Cessation Program
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Smoking Cessation
Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulation Followed by Maintenance Stimulation to Prevent Relapse
Smoking cessation is a public health priority. Tobacco is directly responsible for 75,000 deaths per year in France. Without help, less than 5% of smokers are still abstinent after 12 months of smoking cessation.
- Trial name
- TABACSTIM 3 (NCT05152810)
- Testing
- Transcranial Magnetic Stimulation sessions, Evaluations
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Nicotine Dependence
Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention
The purpose of this research study is to find out if an investigational drug, GSK598809 can help people who have very recently quit smoking; the investigators want to find out if continuing to take GSK598809 over six weeks can…
- Trial name
- NCT01188967
- Testing
- GSK598809
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Relapse-Prevention Booklets as an Adjunct to a Tobacco Telephone Helpline("Quitline")
The study primary purpose is smoking relapse prevention. This study is a collaboration between researchers who developed the relapse-prevention intervention, at the H.
- Trial name
- NCT01352000
- Testing
- Smoking Cessation
- Where
- United States
- Volunteers
- 3,830 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking, Smoking Cessation
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children
The investigators aim to address the following specific aims: Determine the efficacy of Prog in preventing postpartum smoking relapse and reducing smoking relapse risk factors.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction
- Trial name
- NCT04783857
- Testing
- Progesterone 200 MG Oral Capsule
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Minnesota
Smoking Cessation
Smoking Cessation and Relapse Prevention in Women Postpartum
Background: Pregnancy was found to be a significant triggering factor for smoking cessation and the reduction of nicotine consumption, but 50 - 70 % of mothers who stopped smoking during pregnancy resume tobacco smoking after…
- Trial name
- EARLINT-EP3 (NCT00475046)
- Testing
- Motivational Interviewing
- Volunteers
- 2,790 people
- Sponsor
- University Medicine Greifswald
Tobacco Use Cessation, Pregnancy Related
mHealth Intervention to Prevent Postpartum Smoking Relapse
This project aims to develop an adapted and enhanced mHealth couple intervention to prevent post-partum smoking relapse.
- Trial name
- RESPREMO (NCT04207827)
- Testing
- xSmoker app, SMS, Usual Care
- Where
- Romania
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Smoking Cessation
Benefits of a Cognitive Behavioral Therapy Intervention for Smoking Cessation Supported by Virtual Reality Smoking Cue Exposure
Cognitive-behavioral therapy (CBT) combined with medication is an established intervention for smoking cessation. However, long-term abstinence rates of maximum 35% are yielded.
- Trial name
- ViReTa (NCT03707106)
- Testing
- CBT smoking cessation, virtual reality based cue exposure, progressive muscle relaxation
- Where
- 2 sites in Germany
- Volunteers
- 246 people
- Sponsor
- University Hospital Tuebingen
Smoking Cessation
Mindfulness-based Treatment to Prevent Smoking Relapse
Background: Smoking causes a variety of health problems and causes burden to healthcare systems. Even when support is provided, local data suggest that around 50% of biochemically confirmed quitters resume smoking within 6 months…
- Trial name
- NCT03930329
- Testing
- MBRP group
- Where
- Hong Kong
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Schizophrenia, Schizoaffective Disorder
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
Varenicline (Chantix) is a smoking cessation treatment that was approved in 2006 by the FDA for treatment of nicotine dependence and may be particularly beneficial in smokers with schizophrenia or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Smoking
- Trial name
- SCRP (NCT00621777)
- Testing
- Varenicline
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Postpartum Smoking Relapse
Transtheoretic Model, Postpartum Smoking Relapse, Smoking Cessation Intervention
The postpartum period is an important opportunity to improve maternal and fetal health by preventing smoking relapse in women. To achieve this goal, digital platforms, which are the latest technological developments are used.
- Trial name
- NCT05711225
- Testing
- smoking cessation intervention given according to the web-based transtheoretic model during pregnancy on postpartum smoking relapse.
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Semra YILMAZ
Smoking, Smoking Reduction
Preventing Relapse to Smoking Among Prisoners After Release
Prisoners experience huge health inequalities, and their exceptionally high smoking prevalence (five times the national average) contributes significantly to their high mortality.
- Conditions
- Smoking, Smoking Reduction, Electronic Cigarette Use
- Trial name
- PROSPER (NCT04271371)
- Testing
- Not yet developed
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham