Clinical trials: Relapse to Smoking
Smoking Cessation
Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulation Followed by Maintenance Stimulation to Prevent Relapse.
Tobacco control is a Public Health priority. Tobacco is directly responsible for 75,000 deaths per year in France. Without help, less than 5% of smokers are still abstinent within 12 months of quitting.
- Trial name
- TabacStim2 (NCT04591743)
- Testing
- Active TCS, nicotine treatment, Questionnaires
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Substance Dependence
Relapse Prevention Study in Newly Abstinent Smokers
The purpose of this study is to determine the effect of GSK598809 as compared to placebo in preventing recently-quit smokers from going back to smoking.
- Trial name
- NCT00793468
- Testing
- GSK598809, Nicotine Replacement Transdermal Patch
- Where
- 10 sites in United States
- Sponsor
- GlaxoSmithKline
Smoking Cessation, Coronary Artery Disease
Cytisine Compared to Combination NRT in Relapsed Smokers
Cigarette smoking causes cardiovascular disease (CVD) yet many smokers with CVD are unable to quit despite strong desire to do so.
- Trial name
- CYTvsNRT+ (NCT04286295)
- Testing
- Cytisine, Nicoderm C-Q Transdermal Product, Nicorette Lozenge Product
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Smoking
Relapse Prevention Through Social Networking Groups
According to the Census \& Statistics Department, there are still 659,300 daily smokers (11.1%) in Hong Kong. Smoking is addictive, and it is difficult for some motivated smokers to quit without assistance.
- Trial name
- NCT02007369
- Testing
- WhatsApp, Facebook
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The University of Hong Kong
Tobacco Use Cessation, Tobacco Use Disorder
Progesterone & Postpartum Relapse to Smoking
The primary goal of this project is to investigate the potential efficacy of exogenous progesterone (with supplemental relapse prevention counseling) on postpartum relapse in new mothers.
- Trial name
- NCT01798394
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cigarette Smoking
Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)
The central objective of the project is to evaluate the effect of incorporating smoking related contexts into very low nicotine content (VLNC) cigarette extinction trials on clinically relevant, smoking-related outcomes.
- Trial name
- VLNCCue (NCT02538042)
- Testing
- Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (0.07 mg), MCE+
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Francis McClernon, Ph.D.
Nicotine Dependence
Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking
The purpose of this study is to evaluate the efficacy of the glycine antagonist, GW468816, compared with placebo on duration of abstinence and rates of relapse in recently quit female smokers in a randomized, double-blind…
- Trial name
- NCT00218465
- Testing
- GW468816
- Where
- 2 sites in United States
- Volunteers
- 264 people
- Sponsor
- Massachusetts General Hospital
Smoking Cessation
Preventing Postpartum Relapse to Smoking Using Yoga and Cognitive Behavioral Therapy: A Randomized Pilot Study
The purpose of this study is to develop strategies to maintain smoking abstinence initiated in pregnancy and prevent relapse in the postpartum period.
- Trial name
- NCT00360581
- Testing
- Yoga, Yoga and Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nicotine Dependence
Smart Olfaction App to Reduce Relapse
The proposed project aims to refine and test a novel biobehavioral smoking cessation intervention that integrates the strategic application of olfactory stimulation to reduce cigarette craving with an established smartphone-based…
- Trial name
- SOARR (NCT07007195)
- Testing
- Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Houston
Smoking Cessation
Innovations to Prevent Relapse Among Low-income African American Smokers
The purpose of this research is to study a relapse prevention program for adult former smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03982576
- Testing
- Nicotine replacement therapy (NRT), CS-CBT intervention, Path2Quit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Case Comprehensive Cancer Center
Smoking
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
This study evaluates the efficacy and safety of brenipatide when compared to placebo for reducing the risk of relapse to cigarette smoking in adults who have recently quit.
- Trial name
- RENEW-Smk-1 (NCT07223840)
- Testing
- Brenipatide
- Where
- 29 sites in United States, China and 1 more
- Volunteers
- 222 people
- Sponsor
- Eli Lilly and Company
Lung Cancer
Comparison of Nicotine Inhaler and/or Bupropion in Helping People to Stop Smoking and Prevent the Recurrence of Smoking
RATIONALE: Use of a nicotine inhaler and/or bupropion may be effective in helping people stop smoking and prevent them from starting smoking again.
- Trial name
- NCT00033592
- Testing
- bupropion hydrochloride, nicotine
- Where
- 25 sites in United States, Canada
- Volunteers
- 1,708 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Smoking Cessation
Not Quite Ready to Quit
In our communications with the public, the investigators will call this the Not Quite Ready to Quit Smoking Study. One new method to increase quit attempts is to have smokers reduce their cigs/day.
- Trial name
- NCT01866722
- Testing
- Usual care, Reduction, 5Rs
- Where
- United States
- Volunteers
- 560 people
- Sponsor
- University of Vermont
Smoking
Web and Phone Intervention to Maintain Postpartum Tobacco Abstinence
This study seeks to develop and test a Web-based tobacco relapse prevention program targeting postpartum women who quit smoking for pregnancy.
- Trial name
- StayQuit (NCT01864954)
- Testing
- Web+phone
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Oregon Research Institute