Clinical trials: Relationship Dynamics, active
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Bipolar Disorder I or II, Healthy (Controls)
Decoding Emotional Dynamics in Bipolar Disorder
The goal of this neuroimaging study is to investigate how emotional states fluctuate in people with bipolar disorder (BD) compared to healthy controls, and to understand the neural mechanisms driving mood instability.
- Trial name
- NCT07221864
- Testing
- Think and Regulate Affective State Task
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Football, Injury
The Relationship Between Training Dynamics and General Health Status in Veteran Football Players
The goal of this observational study is to learn how training habits and general health status are related to injury risk in veteran football players (men over 35 years old who play recreational football).
- Conditions
- Football, Injury, Veteran
- Trial name
- NCT07027592
- Testing
- Survey Study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Age-Related Macular Degeneration (AMD)
EarLy Treatment Response in nEoVascular Macular Degeneration With Eylea 8mg: ELEV8 A Prospective Observational Open Label Study Investigating the Fluid Dynamics During Early Response to Aflibercept 8mg in Patients With Exudative Age-related Macular Degeneration (AMD).
This prospective, observational, open-label study evaluates early treatment response to intravitreal aflibercept 8 mg in patients with exudative age-related macular degeneration.
- Trial name
- ELEV8 (NCT07434713)
- Testing
- treatment with Aflibercept 8mg (Eylea)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Recurrence
Association Between Irrigation Fluid Absorption and Perioperative cfDNA Dynamics After TURBT
This prospective observational cohort study aims to evaluate the association between intraoperative irrigation fluid absorption and perioperative cell-free DNA (cfDNA) dynamics in patients undergoing transurethral resection of…
- Conditions
- Bladder (Urothelial, Transitional Cell) Cancer, Bladder Cancer Recurrence, Progression of Bladder Cancer, Transurethral Resection of Bladder Tumor
- Trial name
- NCT07589413
- Testing
- Measurement of Intraoperative Irrigation Fluid Absorption and Perioperative cfDNA Profiling
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhiping Wang
Sarcopenia in Elderly, Dysphagia
Relationship Between Swallowing Dynamics and Suprahyoid Muscle Activity in Sarcopenic Dysphagia
Sarcopenic dysphagia is defined as swallowing difficulty among the elderly due to the loss of whole body skeletal and swallowing muscle mass and function.
- Trial name
- NCT07198568
- Testing
- Surface electromyography, Videofluoroscopic swallowing study (VFSS)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Inha University Hospital
Cataract
Small RNA tRF-31 Changes in Patients With Age-Related Cataract
The goal of this observational study is to evaluate the expression characteristics and clinical relevance of the tRF-31/HIPK2 signaling axis in adults over 18 years old with age-related cataract (ARC).
- Trial name
- NCT07672899
- Testing
- Biospecimen collection (Anterior lens capsule)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms
Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study
The goal of this study is to examine changes in blood biomarkers following hyperbaric oxygen therapy (HBOT) in military veterans with traumatic brain injury and persistent post-concussive symptoms.
- Conditions
- Traumatic Brain Injury (TBI) Patients, Post Concussive Symptoms, PTSD
- Trial name
- NCT07849465
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Summit Hyperbarics and Wellness
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
PTSD, Depression
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD.
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- NCT04356274
- Testing
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Pregnancy Related, Pregnancy Loss
Microbiome and Malnutrition in Pregnancy
This study is being conducted to investigate how a mother's nutritional status and her gut microbiome during pregnancy contribute to the birth outcomes and health of her baby.
- Conditions
- Pregnancy Related, Pregnancy Loss, Pregnancy Complications, Pregnancy; Parasitic Disease
- Trial name
- MMIP (NCT04992104)
- Where
- 2 sites in Canada
- Volunteers
- 800 people
- Sponsor
- The Hospital for Sick Children
Pediatric Cancer, Coping Behavior
Coping and Attachment in Pediatric Oncohematology
Cancer can be a traumatic and particularly salient experience in a person's history. The ways in which the pediatric patient copes with it depend on the interaction of several factors present in his or her life context, primarily…
- Conditions
- Pediatric Cancer, Coping Behavior, Relationship, Parent Child
- Trial name
- CopAt (NCT06858163)
- Where
- 3 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Family Dynamics, Family Relations
Dialogical Family Guidance PostDoc Study
This new family intervention, called Dialogical Family Guidance (DFG) is developed to target family needs especially in families with a child with neurodevelopmental disorders.
- Conditions
- Family Dynamics, Family Relations, Family Support
- Trial name
- DFG II (NCT06322511)
- Testing
- Dialogical Family Guidance (DFG)
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Tampere University
Acute Heart Failure (AHF), Heart Failure
Urinary Chloride and Sodium Changes and Residual Congestion in Acute Heart Failure
The goal of this observational study is to learn how changes in urinary sodium and chloride levels relate to fluid overload and short-term outcomes in patients hospitalized with acute heart failure (AHF).
- Conditions
- Acute Heart Failure (AHF), Heart Failure, Congestion
- Trial name
- CLORINA-IC (NCT07597512)
- Where
- 4 sites in Spain
- Volunteers
- 223 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Opioid Use Disorder (OUD)
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
This study aims to understand how ibogaine treatment may change brain activity and symptoms in people with moderate-severe opioid use disorder (OUD), as defined by the DSM-5.
- Trial name
- MIND-OUD (NCT07226570)
- Testing
- Observational study with MRI/EEG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Rare Diseases
A Longitudinal Study on Family Adaptation and Relationship Dynamics in Pediatric Rare Diseases
Rare diseases in children can affect not only the child's health but also the well-being and relationships within the entire family.
- Trial name
- FAIR (NCT07497581)
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Markus A. Landolt
Radiation Enteritis
Plasma GLP-2 Dynamics and Acute Radiation Enteritis After Abdominopelvic Radiotherapy
This prospective observational study will enroll 50 adults who are scheduled to receive radiotherapy to the abdomen or pelvis. The study will not assign any additional treatment or change routine clinical care.
- Trial name
- NCT07759258
- Testing
- Abdominopelvic Radiotherapy
- Volunteers
- 50 people
- Sponsor
- Wang Xinying
Active Outdoor Play and Related Healthy Dietary Behaviours
B-challenged: Co-creating Physical and Social Environments to Promote Children's Active Outdoor Play
BACKGROUND An alarmingly low number of children meet public health guidelines for physical activity and healthy dietary behaviours, and are at increased risk of developing lifestyle-related diseases.
- Trial name
- B-challenged (NCT07136376)
- Testing
- Physical and social environmental interventions.
- Where
- 5 sites in Denmark, Germany and 3 more
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc