Clinical trials: Relatives
Body Weight, Obesity & Overweight
Breastmilk and the Link to Overweight/Obesity and Maternal Diet in the Mother-breastmilk-child Triad
The prospective 5-month follow-up study will involve 150 mother-infant dyads grouped based on maternal baseline BMI category (normal weight, overweight, obesity).
- Conditions
- Body Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
- Trial name
- BLOOM-Triad (NCT07457515)
- Where
- 4 sites in Canada, Poland
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Warsaw University of Life Sciences
Pharmacokinetics
Assess Pharmacokinetics of Fostamatinib in Fed and Fasted State in Combination With Ranitidine to Assess Bioavailability
Study to Assess the Pharmacokinetics of R406 in Healthy Subjects when Fostamatinib 150 mg is Administered Alone in Fed and Fasted state and in Combination with Ranitidine in Fasted State, and to Assess the Relative…
- Trial name
- PK Combination (NCT01682408)
- Testing
- Fostamatinib - 1 x 150mg mannitol-based 38% drug-loaded tablet(orange reference), Fostamatinib - 3 x 50mg microcrystalline cellulose-based 13% drug loaded tablets,(blue) fed, Fostamatinib - 1 x 150mg mannitol based 38% drug-loaded tablet (batch variant A)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteers
First in Man Clinical Trial of Emodepside (BAY 44-4400)
This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers.
- Trial name
- NCT02661178
- Testing
- emodepside (BAY 44-4400)
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Drugs for Neglected Diseases
Healthy Participants
A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healthy Participants
The primary purpose of this study is to determine the relative bioavailability of brensocatib between the pediatric oral solution and oral tablets in healthy participants.
- Trial name
- INS1007 (NCT06344728)
- Testing
- Brensocatib Oral Solution, Brensocatib Oral Tablet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Insmed Incorporated
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Healthy Volunteers
A Study to Evaluate the Relative Bioavailability of Two Formulations of BIIB104 and Assess the Effect of Food on the Pharmacokinetics of BIIB104 Following Administration of a Single, Fixed, Oral Dose of BIIB104 in Healthy Participants
The primary objectives of this study are to evaluate the relative bioavailability of the BIIB104 test formulation compared with the reference formulation in healthy Caucasian male adult participants in the fasted state and to…
- Trial name
- NCT05152485
- Testing
- BIIB104 Reference Formulation, BIIB104 Test Formulation
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biogen
Bioequivalence
Characterisation of Relative Bioavailability With Bioequivalence Assessment of Deferiprone Tablets After Oral Single Dose Administration
The present study will be conducted in order to compare the bioavailability of the generic Test product (Deferiprone 500 Lipomed tablets, Lipomed AG, Switzerland) with a marketed Reference product (Ferriprox® film-coated tablets…
- Trial name
- NCT02980458
- Testing
- Deferiprone 500Mg Tablet, Deferiprone 500 MG Oral Tablet [Ferriprox]
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- SocraTec R&D GmbH
Healthy Participants
A Study to Evaluate the Drug Levels of Abatacept Converted From Drug Substance by Two Different Processes in Healthy Participants
The purpose of this study is to compare the relative absorption of abatacept in healthy participants following subcutaneous (SC) administration in which the drug substance is manufactured with the current or new process.
- Trial name
- NCT05981976
- Testing
- Abatacept
- Where
- 3 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy
GLPG0259 Solid Formulation Bioavailability and Food Effect
The purpose of the study is to compare the pharmacokinetics of GLPG0259 as a solid dosage formulation (with and without food)and an oral solution, and to assess its safety and tolerability.
- Trial name
- NCT01024517
- Testing
- GLPG0259 solution, GLPG0259
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Type 2 Diabetes
A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions
The purpose of this study is to demonstrate the relative bioequivalence of Metformin HCL Tablets, 1000 mg under fasting conditions.
- Trial name
- NCT00865033
- Testing
- Metformin HCL Tablets, 1000 mg Sandoz, Glucophage 1000 mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sandoz
Psychosis
To Demonstrate the Relative Bioequivalency of Generic Haloperidol Tablets Versus Haldol in Normal Volunteers
To demonstrate the relative bioequivalency of generic Haloperidol tablets versus Haldol in normal volunteers.
- Trial name
- NCT00946491
- Testing
- Haloperidol 10 mg Tablets (Cord Laboratories), Haldol 10 mg Tablets (McNeil Pharmaceuticals)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sandoz
Healthy
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets
The purpose of this trial is to demonstrate the relative bioavailability of 2 newly developed fixed dose combinations (FDC) tablets containing empagliflozin, linagliptin \& metformin extended release (XR) and the single tablets…
- Trial name
- NCT02821910
- Testing
- High dose FDC Empagliflozin/Linagliptin/Metformin XR, fed, 1 tab Empagliflozin +1 tab Linagliptin +2 tabs Metformin XR, High dose FDC Empagliflozin/Linagliptin/Metformin XR, fasted
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Carpal Tunnel Syndrome (CTS)
Study of the Carpal Tunnel Syndrome in Relation to Stress and Depression Among Medical Students
Participants will undertake validation of the median nerve and their anxiety and depression levels. Possible correlation will be searched.
- Trial name
- CRS (NCT06758518)
- Testing
- No Interventions
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Healthy
10 mg Donepezil Hydrochloride Orally Disintegrating Tablets Under Non-Fasting Conditions
This study investigated the relative bioavailability (rate and extend of absorption) of Donepezil Hydrochloride Orally Disintegrating Tablets, 10 mg by Teva Pharmaceuticals, USA with that of Aricept® Orally Disintegrating…
- Trial name
- NCT01260948
- Testing
- Donepezil Hydrochloride, Aricept®
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Heart Failure
Relative Bioavailability Study With Enalapril in Healthy Volunteers
Phase I study in healthy adult male and female volunteers to compare the bioavailability of enalapril administered in orodispersible Minitablets with or without water in comparison to the standard galenic tablet formulation of…
- Trial name
- NCT02252692
- Testing
- Enalapril
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ethicare GmbH
HIV Infections
Safety Study of Isentress® + Truvada® in Post-exposure Treatment of HIV Infection
The objective are to assess the nature and incidence of drug intolerance observed with a new antiretroviral triple therapy, Truvada® [0-0-1] + Isentress® 400 mg tablets [1-0-1], prescribed in a setting of the treatment of…
- Trial name
- NCT01114425
- Testing
- raltegravir (Isentress), Truvada®
- Where
- France
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux
Bacterial Infections
Relative Bioavailability Study Of Two Lincomycin Hydrochloride Hard Gelatinous Capsule
To assess the relative bioavailability of two different batches of Frademicina® drug product, containing 500 mg lincomycin hydrocloride, manufactured by Pfizer Laboratories Ltd.
- Trial name
- NCT01058824
- Testing
- Lincomycin
- Where
- 2 sites in Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hypercholesterolemia, CVD
Effect of Plant Sterol Enriched Milk on Plasma Lipid Levels of Humans Breast-fed During Infancy
The overall goal of this clinical study is to investigate how dietary cholesterol intake influences the plasma Total cholesterol (TC), LDL-Cholesterol levels and cholesterol metabolism between adults who had been breast-fed as…
- Trial name
- NCT01825668
- Testing
- Plant Sterols, High cholesterol
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
Bioavailability Study of Tacrolimus Capsules, 5 mg of Dr. Reddy's Under Fasting Conditions
The purpose of this study is to compare the relative bioavailability study of tacrolimus capsules 5 mg with prograf capsules 5 mg in healthy, adult, human subjects under fasting conditions and to monitor safety of subjects
- Trial name
- NCT01131988
- Testing
- Tacrolimus Capsules
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers
To estimate the effects of food on oxycodone pharmacokinetics after administration of 40 mg doses of PF-00345439 Formulation K and to estimate its relative bioavailability compared to PF-00345439 Formulation X in the fasted state…
- Trial name
- NCT01924676
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
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