Clinical trials: Relatives
Healthy
Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers
To estimate the effects of food on oxycodone pharmacokinetics after administration of 40 mg doses of PF-00345439 Formulation K and to estimate its relative bioavailability compared to PF-00345439 Formulation X in the fasted state…
- Trial name
- NCT01924676
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pain Therapeutics
Healthy
A Relative Bioavailability Study of Selpercatinib (LY3527723) in Healthy Participants
The main purpose of this study is to compare the amount of selpercatinib that gets into the blood stream and how long it takes the body to get rid of it, when given as three different formulations in adult healthy participants.
- Trial name
- NCT05136404
- Testing
- Selpercatinib
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Loxo Oncology, Inc.
Healthy Volunteers
Relative Bioavailability and Effect of Food Study With AGMB-129 in Healthy Participants
This is a single-center, open-label, single-dose, randomized, 3-period cross-over, Phase 1 study in healthy adult participants to assess the BA of AGMB-129 tablet formulation relative to that of the reference capsule formulation…
- Trial name
- NCT06397508
- Testing
- AGMB-129
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Agomab Spain S.L.
Healthy Volunteers
A Relative Bioavailability Study of Nicotine Delivery From Selected Oral Nicotine Products
This will be a randomised, cross-over, single-blind, confinement study conducted in 27 male or female snus or nicotine pouch users.
- Trial name
- NCT05452278
- Testing
- Product A, Product B, Product C
- Where
- Sweden
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Imperial Brands PLC
Post-traumatic Stress Disorder (PTSD), Aggressive Behavior
Prevention of Post-Traumatic Stress Disorder in Soldiers
Soldiers in conflict or former conflict regions deployed in peace-keeping missions were and are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior.
- Trial name
- NCT01729325
- Testing
- Preventive Narrative Exposure Therapy
- Where
- Burundi
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Metabolic Syndrome
Coenzyme Q10 and Vitamin A, C, E in Relation to the Oxidative Stress, Antioxidant Enzyme Activity and Inflammation in Subjects With Metabolic Syndrome
Metabolic syndrome (MS) is a significant risk factor of cardiovascular disease. However, the relationships between coenzyme Q10, antioxidant vitamins (Vitamin A, C, E) and the prevention of the risk of MS are still inconsistent.
- Trial name
- NCT01412476
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Healthy Volunteers
A Study to Investigate the Relative Bioavailability of 2 Tablet Formulations and the Effect of Food on the Pharmacokinetics of BGB-58067 in Healthy Participants
This study is being done to understand how the body processes 2 different tablet formulations of the study drug (BGB-58067) and how food intake influences the processing of the study drug by the body.
- Trial name
- NCT07712640
- Testing
- BGB-58067 Tablet (F-01 Formulation), BGB-58067 Tablet (F-02 Formulation)
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- BeOne Medicines
Fecal Incontinence
Safety and Tolerability of a Single Intra-anal Dose of NRL001 in Healthy Volunteers
This study is conducted to explore the safety and tolerability and plasma pharmacokinetics of NRL001 after single intra-anal dose of 1mL cream at increasing concentrations.
- Trial name
- NCT01406925
- Testing
- NRL001 cream
- Where
- Bulgaria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norgine
Healthy Volunteer
A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants
This open-label, randomized, 4-way crossover study in healthy participants will determine the relative bioavailability of the tablet formulation relative to the capsule formulation and the effect of a high-fat and low-fat meal on…
- Trial name
- NCT02856152
- Testing
- GDC-0276 capsule, GDC-0276 tablets
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Colorectal Cancer
Survivorship in Lynch Syndrome Families
Objectives: Specific Aims: 1. Researchers will evaluate and compare predictors of health-related quality of life (QOL) among colorectal cancer (CRC) survivors who have Lynch syndrome (LS) with those patients who have sporadic CRC…
- Trial name
- NCT01126840
- Testing
- Telephone Interview, Questionnaire
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Relative Bioavailability of Pioglitazone After Co-administration With Different Doses of BI 10773 in Healthy Volunteers
The objective was to investigate the effect of different doses of BI 10773 on the bioavailability of pioglitazone after multiple oral doses of both drugs
- Trial name
- NCT02172235
- Testing
- Pioglitazone, Pioglitazone - low dose, BI 10773 - low dose
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Aging
Active Life Engagement in Relation to Health-related Outcomes Among Community-dwelling Chinese Older Adults
This study aims to examine within-person variations of different contexts (time, physical, psychosocial and affective) of active life engagement, and how these variations predict a set of physiological indicators and…
- Trial name
- NCT03518580
- Testing
- real-time assessment of biopsychosocial functioning
- Where
- Hong Kong
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mobile Phone Use
Time Need to Detect Mobile Phone Use to Prevent Muscle Fatigue
Using a smart phone while adopting a poor posture can cause various physical problems. The neck and shoulders are particularly vulnerable to pain due to smart phone use, with the muscles showing a high level of muscle fatigue…
- Trial name
- NCT04641208
- Testing
- mobile phone
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MTI University
Iron Deficiency
Relative Bioavailability of Ferric Pyrophosphate From an Apple Juice Drink
The aim of this study is to find out how well iron is absorbed when a newly developed form of ferric pyrophosphate is added to a commercial apple juice drink.
- Trial name
- NCT00474682
- Testing
- Micronized dispersible ferric pyrophosphate
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Healthy
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets
The purpose of this trial is to demonstrate the relative bioavailability of 2 newly developed fixed dose combinations (FDC) tablets containing empagliflozin \& metformin XR and the single tablets of empagliflozin and metformin XR…
- Trial name
- NCT02106923
- Testing
- 1 tablet Empagliflozin/2 tablets Metformin XR, 10 mg Empagliflozin/1000 mg Metformin XR, 1 tablet 10 mg Empagliflozin/3 tablets Metformin XR
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Bioequivalence Study of Fenofibrate 160mg Tablets Under Fed Conditions
The objective of this study was to compare the single-dose relative bioavailability of Ranbaxy and Abbott (TriCor) 160 mg fenofibrate tablets under fed conditions.
- Trial name
- NCT00775359
- Testing
- Fenofibrate 160 mg tablets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Type 2 Diabetes Mellitus
Influence of Glucagon Inhibition in Relation to the Anti-Diabetic Effect of Glucagon-Like Peptide-1 (GLP-1) in Patients With Type 2 Diabetes Mellitus
Incretinbased treatment of patients with type 2 diabetes mellitus (T2DM) has increasing interest. The incretin glucagon-like peptide-1 (GLP-1) stimulates beta-cells to increased secretion and production of insulin.
- Trial name
- NCT00655603
- Testing
- Infusion of native hormones from the pancreas and gut (GLP-1)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
To Determine Bioequivalence Under Fed Conditions
Bioavailability Study of Leflunomide Tablets Under Fed Conditions
To compare the single-dose Bioavailability of Kali and Aventis
- Trial name
- NCT00653003
- Testing
- Leflunomide, ARAVA
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Hereditary Angioedema
A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161
The purpose of the study is to compare how the body takes up and then eliminates the study drug BCX4161 when it is taken orally as a hard gelatin capsule and as a soft gelatin capsule.
- Trial name
- NCT02125162
- Testing
- BCX4161
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BioCryst Pharmaceuticals
Patello Femoral Syndrome
Relation Between Femoral Nerve Conduction Velocity and Its Mechanosensitivity Changes Among Patellofemoral Pain Syndrome
1. to investigate the relation between NCV of femoral nerve and other dependent variables such as ( pain \& limited hip extension ROM )in patients with PFPS . 2.
- Trial name
- NCT04624542
- Testing
- Electromyographic device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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