Clinical trials: Remifentanil
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Sedative Adverse Reaction
Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry
The purpose of this university study is to evaluate the use of an advanced dental sedation technique involving two syringe-type pumps called Target Controlled Infusion (TCI) pumps.
- Trial name
- NCT03995134
- Testing
- Propofol and Remifentanil administered by TCI pump
- Where
- 2 sites in Canada, New Zealand
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Rhinoplasty, Dexmedetomidine
Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
The investigators compared the effects of remifentanil and dexmedetomidine administered under general anesthesia on hemodynamics, postoperative pain, recovery, postoperative nausea, vomiting, shivering, patient's and surgeon's…
- Conditions
- Rhinoplasty, Dexmedetomidine, Remifentanil
- Trial name
- NCT05572723
- Testing
- Remifentanil 2 MG, dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Anesthesia, General, Anesthesia, Intravenous
Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the…
- Trial name
- NCT02492282
- Testing
- Closed-Loop propofol and remifentanil system by Bispectral Index, Open-Loop propofol and remifentanil by Target Controlled Infusion, propofol
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Acute Pain, Respiration
Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers
The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model.
- Conditions
- Acute Pain, Respiration, Sedation
- Trial name
- Remiclon (NCT00730054)
- Testing
- Remifentanil+clonidine
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cognitive Ability, General
Relationship Between Cognitive Function and Pain
Patients with chronic pain can experience considerable changes in their cognitive function such as forgetfulness, increased absentmindedness, confusion etc. Opioids (e.g.
- Trial name
- NCT01375348
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Valvular Heart Disease
Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity
The purpose of this study is to determine desflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery.
- Trial name
- NCT02003885
- Testing
- increment of desflurane
- Where
- South Korea
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Labour Pain, Satisfaction
Remifentanil as Intravenous Patient-controlled Analgesia (IVPCA) During Labour
Remifentanil is a ultra short-acting synthetic opioid. It is rapidly metabolized by non-specific blood and tissue esterases. We wanted to investigate the efficacy and safety of remifentanil used as analgesia during labour.
- Conditions
- Labour Pain, Satisfaction, Adverse Effects
- Trial name
- NCT00202722
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Hyperalgesia
The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiSun 1 (NCT00811837)
- Testing
- Midazolam, Remifentanil
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pharyngeal Dysfunction, Pharyngeal Swallowing
Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers
The purpose of the study is to determine whether remifentanil influence the pharyngeal phase of swallowing using using pressure and impedance recordings.
- Trial name
- NCT01924234
- Testing
- Morphine, Remifentanil
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Thyroidectomy
Optimal Concentration of Remifentanil for NIM Tube Intubation With Low-dose NMBA
During thyroid surgery, Intraoperative Neuromonitoring (IONM) plays a crucial role in preventing serious complications such as bilateral vocal cord paralysis.
- Trial name
- NCT06162390
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Acute Cholecystitis
The Comparison of Hemodynamic Effects Between Remimazolam-remifentanil and Propofol-remifentanil in Patients Undergoing Laparoscopic Cholecystectomy
This study is conducted to determine whether the occurrence of hypotension is reduced by the combined use of remimazolam and remifentanil compared to the conventional combination use of propofol and remifentanil.
- Trial name
- NCT05164159
- Testing
- propofol group, remimazolam group
- Where
- South Korea
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hyperalgesia, Secondary
Modulation of Remifentanil-induced Postinfusion Hyperalgesia
In addition to alleviate pain there is growing evidence that µ-opioids enhance pain. This problem is known as opioid induced hyperalgesia(OIH).The NMDA receptor is involved in opioid induced hyperalgesia it may be possible to…
- Trial name
- NCT00785863
- Testing
- Remifentanil, Ketorolac and remifentanil, Parecoxib and remifentanil
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Elective Thyroidectomy
Effect of Remifentanil on Cough During Emergence From General Anesthesia : Trial to Compare Between Sevoflurane Anesthesia and Propofol Anesthesia
The objective of this study was to compare the effect of remifentanil on suppression cough reflex during emergence in patient anesthetized using either propofol or sevoflurane additionally under infusion of the identical…
- Trial name
- NCT01240109
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hemodynamic Instability, Intubation Complication
Effect-site Concentration of Remifentanil for Double-lumen Tubes Intubation: Airtraq VS Macintosh Laryngoscope
The 50% effective concentration of remifentanil by target controlled infusion was not determined for inhibiting the haemodynamic response during double-lumen tube (DLT) intubation.
- Trial name
- NCT03653910
- Testing
- Airtraq, Macintosh
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Cholecystolithiasis
Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI)
Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to…
- Trial name
- DLTCI (NCT02116985)
- Testing
- Dual-loop TCI, manual
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Hyperalgesia
Opioid-induced Hyperalgesia After Remifentanil Infusion
Remifentanil is a rapid-acting opioid which has been widely used in pain treatment during surgery for the last 15 years 1. Remifentanil is rapidly eliminated (minutes) from the body after end of infusion, and this makes it easily…
- Trial name
- NCT01702389
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Postoperative Pain
Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Intubation is a procedure that requires well relaxed muscles while general anesthesia is performed. In order to get adequate muscle relaxation, remifentanil, sevoflurane or both agents in combination have been reported as they…
- Trial name
- NCT02440204
- Testing
- Intubation, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Obstructive Sleep Apnea
Remifentanil in Children With Obstructive Sleep Apnea
This investigation tested the hypothesis that children with obstructive sleep apnea have an increased pharmacodynamic sensitivity to the miotic and respiratory depressant effects of the prototypic μ-opioid agonist remifentanil.
- Trial name
- ROSA (NCT03958396)
- Testing
- Remifentanil Infusion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine