Clinical trials: Remimazolam
Coronary Artery Bypass Grafting, Remimazolam
Remimazolam for Postoperative Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac severe arrhythmia globally and is associated with an increased risk of mortality and morbidity, with a loss of 6.0 million disability-adjusted life-years worldwide in 2017…
- Trial name
- RePAF (NCT05891145)
- Testing
- Remimazolam, midazolam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Flumazenil Adverse Reaction, Ambulatory Surgery
Reversal of Remimazolam by a Single Dose of Flumazenil
Remimazolam, a brand-new sedative which has benzodiazepine property. It is an ultra-short acting sedative and regarded as a proper drug for procedural sedation.
- Conditions
- Flumazenil Adverse Reaction, Ambulatory Surgery, Postoperative Nausea, Remimazolam
- Trial name
- NCT05382806
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Emergence Agitation, Remimazolam
Effect of Remimazolam vs Sevoflurane Anesthesia on Incidence of Emergence Agitation and Complications in Children Undergoing Ophthalmic Surgery
As a novel ultra-short-acting benzodiazepines drugs, Remimazolam has been accepted for induction and maintenance of clinical anesthesia.
- Conditions
- Emergence Agitation, Remimazolam, Sevoflurane, Pediatric Ophthalmic Surgery
- Trial name
- NCT05527314
- Testing
- Remimazolam, Sevoflurane, Fentanyl
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Remimazolam, Body Composition
Body Composition Analysis and Time to Emergence From Remimazolam
Remimazolam is a novel general anesthetic drug. The time to emergence from remimazolam-based general anesthesia is variable among patients, but little is known about the risk factors for delayed emergence.
- Trial name
- NCT05512559
- Testing
- body composition analysis
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Remimazolam, Orthopedic Procedures
Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia
Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages.
- Conditions
- Remimazolam, Orthopedic Procedures, Sedatives, Anesthesia, Spinal
- Trial name
- NCT05379777
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Asan Medical Center
Emergence Agitation, Remimazolam Besylate
Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery
Emergence agitation (EA) is a transient, self-limited, non-fluctuating state of psychomotor excitement, which closely revolves around the emergence of general anesthesia.
- Conditions
- Emergence Agitation, Remimazolam Besylate, Perioperative Sedation, Laparoscopic Abdominal Surgery
- Trial name
- NCT05624424
- Testing
- Rematazolam Besylate, Propofol, Sevoflurane
- Where
- 6 sites in China
- Volunteers
- 1,317 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
General Anesthesia, Electroencephalography
Electroencephalographic Profiles During General Anesthesia: a Comparative Study of Remimazolam and Propofol
How anesthetic drugs induce and maintain the behavioral state of general anesthesia is an important question in medicine and neuroscience.
- Conditions
- General Anesthesia, Electroencephalography, Laparoscopic Cholecystectomy, Remimazolam
- Trial name
- NCT05533567
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
General Anesthesia, Laparoscopic Cholecystectomy
Differential Effects of Remimazolam and Propofol on Dynamic Cerebral Autoregulation During General Anesthesia
Cerebral autoregulation (CA) is the property of the cerebral vascular bed to maintain cerebral perfusion in the presence of changes in blood pressure.
- Conditions
- General Anesthesia, Laparoscopic Cholecystectomy, Remimazolam, Propofol
- Trial name
- NCT05533580
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Remimazolam Benzenesulfonate on Nenhanced Recovery After Surgery, Possible Molecular Mechanism of Remimazolam Benzenesulfonate
Effect and Mechanism of Remimazolam Benzenesulfonate on Enhanced Recovery After Surgery in Patients Undergoing Radical Gastrectomy for Gastric Cancer
The purpose of this study is to discuss the benzene sulfonic acid red horse azole shimron the occurrence of postoperative complications in patients with gastric cancer radical and its severity, at the same time, comparing the…
- Trial name
- NCT05559151
- Testing
- Remimazolam Benzenesulfonate
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhonghua Chen,MD
Remimazolam, Orthopedic Procedures
ED90 of Remimazolam Loading Dose for Sedation in Patients Under Monitored Anesthetic Care
Currently used drugs for monitored general anesthesia include propofol, midazolam, and dexmedetomidine. Each drug has different advantages and disadvantages.
- Conditions
- Remimazolam, Orthopedic Procedures, Sedatives
- Trial name
- NCT05340335
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Remimazolam, Anesthesia, General
Bispectral Index and Patient State Index During General Anesthesia With Remimazolam
The aim of this study is to compare the bispectral index (BIS) and patient state index (PSI) during general anesthesia using remimazolam.
- Conditions
- Remimazolam, Anesthesia, General, Hypnotics and Sedatives, Thyroid Disease
- Trial name
- NCT05432050
- Testing
- Bispectral index and Patient state index monitoring
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy
This study aims to compare the safety and efficacy of remimazolam and propofol in EUS-FNA/FNB sedation. This study is a prospective, single-blind study.
- Conditions
- Endoscopic Ultrasonography-guided Fine Needle Aspiration, Sedation Complication, Remimazolam
- Trial name
- NCT05437497
- Testing
- Remimazolam Injection, Propofol Injection
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Remimazolam
The Effect of Remifentanil on ED95 of Remimazolam for Loss of Consciousness in Adult Patients
This study prospectively uses the biased coin technique to investigate the effect of concomitant administration of remifentanil on the 95% effective dose of intravenous remimazolam (Effective dose 95 [ED95]) required for loss of…
- Trial name
- NCT05434494
- Testing
- Remimazolam, remifantanil
- Volunteers
- 80 people
- Sponsor
- Ajou University School of Medicine
Day Surgery, Patient Outcome Assessment
Effects of Remimazolam on Quality of Recovery After Ambulatory Surgery
Remimazolam is a novel ultra-short acting benzodiazepine with rapid onset of effects, short maintenance and faster recovery time.
- Conditions
- Day Surgery, Patient Outcome Assessment, Quality of Recovery, Remimazolam
- Trial name
- NCT05320016
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Bundang Hospital
Sedation Complication, Midazolam
Remimazolam Tosilate Sedation and Midazolam Sedation in Dental Patients
Remimazolam Tosilate is a new short-acting benzodiazepines used in sedation. It has the advantages of rapid metabolism, quick recovery without injection pain.
- Conditions
- Sedation Complication, Midazolam, Remimazolam
- Trial name
- NCT04602845
- Testing
- Fentanyl, Flurbiprofen, Midazolam
- Where
- 2 sites in China
- Volunteers
- 81 people
- Sponsor
- Peking University