Clinical trials: Remineralization
White Spot Lesion
Remineralization Effect Of Egg Shell Versus Fluoride Varnish On Early Carious White Spot Lesions In Primary Teeth
The goal of this clinical trial is to to assess the remineralization potential of Egg shell hydrogel versus fluoride varnish in early carious white spot lesions in anterior primary teeth.
- Trial name
- NCT06932926
- Testing
- Egg shell hydrogel, Fluoride varnish
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Remineralization of Early Carious Lesion Using Natural Agents Versus Bioadhesive Polymers
This study will be conducted to evaluate: 1. The remineralization potential of natural agents (egg shell powder and clove extract) versus bioadhesive polymers (carbopol and carboxymethyl cellulose) with or without PH cycling…
- Trial name
- NCT04390256
- Testing
- Clove water extract, Carbopol, Carboxymethyle cellulose
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
To Determine the Ability of a New Product Formulation to Remineralize an Early Caries Lesion by an In-situ Study
This is a double blind, cross-over, controlled clinical trial utilizing thirty (30) adults to evaluate remineralization of early caries lesions.
- Trial name
- NCT02388178
- Testing
- Control toothpaste containing no anti-cavity ingredients, Experimental toothpaste containing fluoride and amino acid (arginine), Fluoride toothpaste containing fluoride as the anti-cavity ingredient
- Volunteers
- healthy volunteers welcome
- Sponsor
- Colgate Palmolive
White Spot Lesion
Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions
The aim of this study is to evaluate the remineralization potential of pearl powder on early ('white spot') lesions in enamel in orthodontic patients compared to casein phosphopeptide-amorphous calcium phosphate.
- Trial name
- NCT03976583
- Testing
- Cpp-Acp, Pearl powder
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cairo University
Remineralization, Enamel Lesions
Clinical Study to Evaluate Remineralization Using an in Situ Model.
This is a phase III clinical trial that aims to evaluate the enamel remineralization efficacy of three dentifrices on artificial caries lesions using an in situ model.
- Conditions
- Remineralization, Enamel Lesions, Enamel Subsurface Lesion
- Trial name
- REMINSITU (NCT07625670)
- Testing
- Fluoride toothpaste containing 750 ppm MFP in a Dical base, Fluoride toothpaste containing 1450 ppm MFP in a Dical base, Fluoride-free toothpaste in a Dical base
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
White Spot Lesion
Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesions
Clinical assessment of the effectiveness of two treatment modalities (self-assembling peptide (P11-4) (alone or combined with fluoride) and resin infiltration) for treating white spot lesions
- Trial name
- NCT06708481
- Testing
- P11-4, a self-assembling peptide, P11-4, a self-assembling peptide with flouride, resin infilteration
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- October 6 University
Tooth Erosion
In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste
This will be a randomized, controlled, single center, single- blind, 3 period, 3 treatment, cross-over, in situ design which consists of placing pre-eroded bovine enamel specimens intra orally using a palatal appliance and…
- Trial name
- NCT03296072
- Testing
- 0.254% w/w sodium fluoride and 5% KNO3, 0.454% w/w stannous fluoride, 5% KNO3
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Enamel Subsurface Lesion
Effects of a Chewing Gum Containing POs-Ca and Fluoride on Enamel
There were no differences in the degree of enamel remineralization of subsurface lesions among the chewing gums containing or not containing POs-Ca and fluoride.
- Trial name
- NCT01377493
- Testing
- chewing gum
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tokyo Medical and Dental University
Tooth Demineralization
Study of Treatments Used for White Spot Lesions After Orthodontic Treatment.
The purpose of this study is to learn more about the management of white spot lesions that occur after orthodontic treatment. White spot lesions generally improve slightly with time.
- Trial name
- NCT01059058
- Testing
- MI Paste Plus, PreviDent Fluoride Varnish, Normal Home Care
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Erosion, Acid Wear
Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion
The purpose of this study is to compare and evaluate the ability of two European Union (EU) regulated gel to foam toothpaste formulations versus a non-fluoride toothpaste using a modified in-situ model of dental erosion and…
- Trial name
- NCT01657903
- Testing
- Sodium Fluoride, Potassium nitrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Caries
In Situ Caries Efficacy of Fluoride Toothpastes
This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model
- Trial name
- NCT00708097
- Testing
- NaF, NaMFP
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Deep Caries
Remineralization of Caries Affected Dentin
Remineralization of carious affected dentin
- Trial name
- NCT04262076
- Testing
- Pulpine with Polyamidoamine Dendrimer
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP
This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.
- Trial name
- REEPP-WSC (NCT03963791)
- Testing
- Eggshell powder gel, CPP-ACP crème
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
In-situ Clinical Trial Assessing Ability to Detect and Monitor Active Caries and Their Remineralization
The goal of this clinical trial is to evaluate whether BlueCheck® can accurately detect and monitor early-stage dental caries (tooth decay) and their remineralization in adults.
- Trial name
- NCT07100626
- Testing
- BlueCheck
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Incisive Technologies Pty Ltd
White Spot Lesions
Effect of Nanohydroxyapatite Paste After Different Pretreatment Techniques on White Spot White Spot Lesions
forty teeth diagnosed with white spot lesions in children aged between 10-14 years old were selected to compare between the effect of using nanohydroxyapatite paste applicatio either alone or preceded by the application of HCl…
- Trial name
- NCT06834464
- Testing
- Nanohydroxyapatite paste, HCl liquid, microabrasion
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
White Spot Lesion
Effect of Different Remineralization Gels
The aim of the study is to treat white spot lesions that occur after orthodontic treatment. Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18.
- Trial name
- NCT05868603
- Testing
- Remineralization gel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
White Spot Lesion of Tooth
Bioactive Glass in the Treatment of Enamel White Spot Lesions
the aim of this study is to evaluate the effectiveness of BiominF® and Novamin® in comparison to Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in the treatment of enamel white spot lesions
- Trial name
- NCT04401280
- Testing
- BiominF, Novamin, CPP-ACP
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rania Salah
White Spot Lesions
Remineralization Potential of Ginger and Rosemary Herbals Versus Sodium Fluoride in Treatment of White Spot Lesions
To evaluate the effectiveness of ginger and rosemary herbals versus sodium fluoride in remineralization of incipient enamel caries.
- Trial name
- NCT03990935
- Testing
- ginger and rosemary gel
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University