Clinical trials: Remote Ischaemic Conditioning
Cerebral Small Vessel Diseases
Effects of Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation, Blood Pressure and Heart Rate Variability in Patients With Cerebral Small Vessel Disease
The purpose of this study is to determine effects of remote ischemic conditioning on dynamic cerebral autoregulation, blood pressure and heart rate variability in patients with cerebral small vessel disease.
- Trial name
- ESCAPE-SVD (NCT05225948)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Hemorrhagic Shock
Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock
The purpose of the study is to evaluate whether remote ischemic conditioning is a safe and effective intervention to prevent the development of inflammation and coagulopathy in trauma patients with hemorrhagic shock.
- Trial name
- NCT02071290
- Testing
- Pneumatic tourniquet
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Remote Ischemic Conditioning
Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation
The purpose of this study is to determine the effect of remote ischemic conditioning on cerebral autoregulation in patients undergoing cerebrovascular stent implantation.
- Trial name
- NCT05970653
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Yi Yang
Ischemic Heart Disease
Effects of Remote Ischemic Conditioning on Myocardial Perfusion in Humans
Cardiovascular disease is the second leading cause of death in Denmark, and ischemic heart disease accounts for the bulk of it. The purpose of this study is to clarify whether a mechanical method of remote ischemic conditioning…
- Trial name
- CONDI-PET (NCT02230098)
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Pre-Eclampsia; Mild, Gestational Hypertension
Effect of RIC on BP and Inflammatory Response in Women With Pre-eclampsia
The aim of this pilot cohort study is to investigate whether treatment with remote ischemic conditioning (RIC) has a beneficial effect on blood pressure as well as the immune system in pregnant women with newly diagnosed…
- Trial name
- NCT03323762
- Testing
- Remote Ischaemic Conditioning (RIC)
- Where
- 3 sites in Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Stroke, Acute
r-tPA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke Recovery
to detect the efficiency and safety of intravenous rtPA combined with RIPC in acute ischemic stroke patients
- Trial name
- rtPA-RIC (NCT02886390)
- Testing
- ischemic conditioning
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Ischemia-Reperfusion Injury
Remote Ischemic Conditioning Using the autoRIC
The purpose of the study is to evaluate the hypothesis that patients receiving remote ischemic conditioning using the autoRIC device show statistically significant reduction in the prevalence of ischemia-reperfusion injury to the…
- Trial name
- SHIELD (NCT03318575)
- Testing
- autoRIC
- Where
- 16 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- CellAegis US, Inc.
End-stage Renal Disease
The Protective Effect of Remote Ischemic Conditioning on Residual Renal Function in Hemodialysis Patients (RIC-HD)
Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease. However, factors such as hemodynamic instability can lead to gradual loss of residual renal function (RRF) in HD patients.
- Trial name
- RIC-HD (NCT06275152)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yuanjun Yang
Atrial Fibrillation
Effect of Remote Ischemic Preconditioning on Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Graft Surgery
Atrial fibrillation is the most common arrhythmic complication after coronary artery bypass grafting (CABG). Post operative atrial fibrillation (POAF) increases morbidity and mortality.
- Trial name
- NCT01500369
- Testing
- sphygmomanometer cuff inflations, standard of care
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- Baystate Medical Center
Acute Ischemic Stroke
Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke Due to Large Artery Atherosclerosis
Large Artery Atherosclerosis is one of the most prevalent causes of stroke worldwide and is associated with a high risk of disability and recurrent strokes.
- Trial name
- RIC-LAA (NCT06775782)
- Testing
- Remote Ischemic Conditioning (RIC) treatment, Medical Management
- Where
- China
- Volunteers
- 1,150 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Remote Ischemic Conditioning
The Impact of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Healthy Adults
The purpose of this study is to determine the impact of serial remote ischemic conditioning on dynamic cerebral autoregulation and related hematology indexes in healthy adults.
- Trial name
- NCT04899362
- Testing
- BB-RIC-D1/LAPUL Medical Devices Co, Ltd, China, Intravenous blood collection, dCA measurement
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Stroke, Acute, Ischemic Stroke
Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke
This study aims to investigate whether Remote Ischemic Conditioning (RIC) improves rheo-erythrocrine dysfunction in acute ischemic stroke
- Conditions
- Stroke, Acute, Ischemic Stroke, Cerebrovascular Disorders, Central Nervous System Diseases
- Trial name
- ENOS (NCT04266639)
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Grethe Andersen
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1)
Currently, early reperfusion is considered as the most effective therapy for the treatment of acute ischemic stroke (AIS). Over the past 20 years, intravenous tissue plasminogen activator (IV tPA) has been demonstrated to be the…
- Trial name
- NCT03210051
- Testing
- Remote ischemic conditioning, Endovascular treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Unilateral Cerebral Palsy, Hemiplegic Cerebral Palsy
Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability
Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's independence.
- Conditions
- Unilateral Cerebral Palsy, Hemiplegic Cerebral Palsy, Remote Ischemic Conditioning
- Trial name
- NCT05355883
- Testing
- Remote Ischemic Conditioning (RIC), Hand Arm Bimanual Intensive Therapy (HABIT), Bimanual Cup Stacking Training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- East Carolina University
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning combined with intravenous thrombolysis in treating acute ischemic stroke.
- Trial name
- NCT04980625
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 558 people
- Sponsor
- Yi Yang
Traumatic Brain Injury, Brain Injuries
Remote Ischemic Conditioning in Traumatic Brain Injury
Traumatic brain injury (TBI) is a leading cause of death among trauma patients accounting for one-third of all trauma mortalities.
- Conditions
- Traumatic Brain Injury, Brain Injuries, Brain Trauma, Brain Injuries, Traumatic
- Trial name
- MOTION (NCT03899532)
- Testing
- Remote Ischemic Conditioning, No-Remote Ischemic Conditioning
- Where
- United States
- Sponsor
- University of Arizona
Adult Patients With Septic Shock Admitted in Intensive Care Unit
Remote Ischemic Postconditioning in Septic Shock
Septic shock is a leading cause of death worldwide despite intensive research efforts. Only a few interventions have been proven to be effective in improving patient-centered outcomes.
- Trial name
- RIPOST-sepsis (NCT07273942)
- Testing
- Remote ischemic conditioning, No intervention
- Where
- 23 sites in France
- Volunteers
- 720 people
- Sponsor
- Hospices Civils de Lyon
Old Age, Mobility Limitation
RIC (Remote Ischemic Conditioning) in Older Individuals
The purpose of this study is to examine the feasibility and acceptability of a technique called remote ischemic conditioning (RIC) that aims to improve muscle strength, muscle mass, exercise tolerance, resilience (i.e.
- Conditions
- Old Age, Mobility Limitation, Debility
- Trial name
- NCT06476288
- Testing
- Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
COVID, Corona Virus Infection
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
This research aims to assess the use of an experimental and non-invasive procedure, Remote Ischemic Conditioning (RIC), as an adjunct therapy in attenuating severe COVID-19 disease.
- Conditions
- COVID, Corona Virus Infection, Acute Lung Injury, Ischemia Limb
- Trial name
- NCT04659460
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Coronary Artery Bypass, Myocardial Reperfusion Injur
Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome.
This study evaluates the addition of remote ischemic preconditioning and postconditioning to standard myocardial protection protocol in patients submitted to off - pump coronary artery bypass grafting in a prospective, 1:1…
- Conditions
- Coronary Artery Bypass, Myocardial Reperfusion Injur, Ischemic Preconditioning, Myocardial, Ischemic Postconditioning
- Trial name
- RICARDO (NCT03363958)
- Testing
- Remote Ischemic Preconditioning with Postconditioning
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medinet Heart Centre