Clinical trials: Remote Ischaemic Preconditioning
Ischemic Reperfusion Injury
Single-cycle Remote Ischemic Preconditioning and Postconditioning for Prevention of Contrast-Induced Nephropathy
This trial is a 2 x 2 factorial design, double-blinded, randomized controlled trial to evaluate efficacy and safety of remote ischemic preconditioning and postconditioning for prevention of contrast-induced acute kidney injury in…
- Trial name
- NCT02729155
- Testing
- RIPre, RIPost
- Where
- Thailand
- Volunteers
- 596 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Contrast-induced Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast-Induced Kidney Injury in Diabetic Patients (PRINCES)
This study investigates whether remote ischemic preconditioning (RIPC)-a non-invasive technique involving brief cycles of blood flow restriction to the arm-can prevent contrast-induced nephropathy (CIN) in diabetic patients…
- Trial name
- PRINCES (NCT07179874)
- Testing
- Remote Ischemic Preconditioning
- Volunteers
- 71 people
- Sponsor
- Universidad de Murcia
Pain
Remote Ischemic PreConditioning Effect on Postsurgical Pain
Remote Ischemic PreConditioning (RIPC) will improve the postoperative pain experience in patients undergoing abdominal surgery. Although abdominal surgery can be a lifesaving procedure many people have a significant amount of…
- Trial name
- RIPCEPP (NCT01383317)
- Testing
- Thigh Tourniquet (VBM Single Use Tourniquet Cuff Items 20-34-722SLZ-1)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Wake Forest University Health Sciences
Aortic Valve Stenosis
Protection by Remote Ischemic Preconditioning During Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) has rapidly been adopted into clinical practice, but concerns have been raised regarding periprocedural complications like e.g. myocardial injury, stroke or acute kidney injury.
- Trial name
- NCT02080299
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital, Essen
Atrial Fibrillation, Ventricular Arrythmias
Effect of Remote Ischemic Preconditioning on Cardiac Function After Cardiac Surgery
The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cardiac function in patients undergoing cardiac surgery compared to control intervention.
- Conditions
- Atrial Fibrillation, Ventricular Arrythmias, Myocardial Injury, Cardiac Function
- Trial name
- NCT00882622
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Germany
- Sponsor
- Patrick Meybohm
Aortic Dissection Type A
Remote Ischemic Preconditioning for Aute Type A Aortic Dissection Surgery
The goal of this clinical trial is to learn if a technique called remote ischemic preconditioning (RIPC) helps protect organs during emergency surgery for acute type A aortic dissection (ATAAD).
- Trial name
- NCT07383909
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- 16 sites in China
- Volunteers
- 1,312 people
- Sponsor
- Fujian Medical University
HF - Heart Failure
Acute Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Vascular Parameters in Patients With Suspected Heart Failure With Preserved Ejection Fraction
The PIRIC-FEp study will be a randomized clinical trial in sedentary patients with suspected heart failure with preserved ejection fraction.
- Trial name
- PIRIC-FEp (NCT07365501)
- Testing
- remote ischemic preconditioning
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- University of Castilla-La Mancha
Myocardial Infarction
Remote Ischemic Preconditioning in Primary PCI
Primary percutaneous coronary intervention (pPCI) is the preferred treatment in ST elevation myocardial infarction (STEMI). The infarct-related artery (IRA) can be opened in more than 90% of the patients.
- Trial name
- NCT00435266
- Testing
- Remote ischemic preconditioning
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Coronary Heart Disease
Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery
Coronary heart disease (CHD) is the leading cause of death in the UK, accounting for 124,000 deaths (2006) and costing the UK economy over £7.9 billion a year.
- Trial name
- ERICCA (NCT01247545)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- 28 sites in United Kingdom
- Volunteers
- 1,612 people
- Sponsor
- University College, London
Bilateral Limb Ischemic Preconditioning, Intracranial Arterial Stenosis
Feasibility, Safety and Efficacy of Remote Ischemic Preconditioning for Symptomatic Intracranial Arterial Stenosis in Octogenarians
Making a limb transiently ischemic induces ischemic tolerance in distant organs such as the heart. This study aims to evaluate the feasibility, safety and initial efficacy of using briefly repetitive bilateral limb ischemic…
- Trial name
- NCT01570231
- Testing
- bilateral limb ischemic preconditioning (Doctormate, IPC-906X)
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Ji Xunming
Burn Injury, Acute Wound
Cutaneous Microcirculation After Remote Ischemic Preconditioning
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound
- Trial name
- NCT02417805
- Testing
- Intervention: Remote Ischemic Preconditioning
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Peripheral Arterial Disease
A Study on the Phenomenon of Remote Ischaemic Preconditioning in Patients With Peripheral Artery Disease
This study aims to evaluate whether remote ischemic preconditioning (RIPC) daily for 28 days reduces the symptoms of intermittent claudication in patients with peripheral artery disease (PAD).
- Trial name
- NCT05084066
- Testing
- Repeated remote ischemic preconditioning
- Where
- Estonia
- Volunteers
- 42 people
- Sponsor
- Tartu University Hospital
Congenital Heart Disease, Cardiopulmonary Bypass
Seattle Cardiorenal Remote Ischemic Preconditioning Trial
Remote Ischemic Preconditioning (RIPC) is a treatment that may be associated with improved outcomes after cardiac surgery. It can be elicited noninvasively by using a tourniquet to elicit transient ischemia over a lower…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Myocardial Injury, Acute Kidney Injury
- Trial name
- SCRIPT (NCT01260259)
- Testing
- RIPC, Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Hypertension, Vascular Diseases
The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
The purpose of this study is to assess whether remote ischaemic conditioning, applied chronically, improves vascular health in older adults
- Trial name
- RIPCo (NCT05971407)
- Testing
- Remote Ischaemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cardiotoxicity
Remote Ischaemic Preconditioning in Childhood Cancer
Survival rates of children with cancers have improved significantly in the recent few decades. Nonetheless, the side effect of this class of drugs on heart function remains to be an issue of concern.
- Trial name
- NCT03166813
- Testing
- Remote Ischaemic Preconditioning, Control
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Coronary Artery Bypass
Remote Ischemic Preconditioning in Type 2 Diabetic Patients Undergoing CABG
This randomized, double-blind, prospective clinical trial aims to investigate the effect of remote ischemic preconditioning (RIPC) on myocardial protection in patients with type 2 diabetes mellitus undergoing elective coronary…
- Conditions
- Diabetes Mellitus, Coronary Artery Bypass, Remote Ischaemic Conditioning
- Trial name
- NCT06977230
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
Ischemia
Trial of the Effects of Remote Preconditioning on the Tissue Metabolism During Exercise and Ischemia
Previously, the preconditioning signaling pathways have been studied on molecular level or in animal model. By using MR spectroscopy and imaging in a dynamic human model of preconditioning, we will have a better understanding how…
- Trial name
- NCT00791206
- Testing
- Real preconditioning
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Osteoarthritis, Hip, Cardiovascular Diseases
Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.
Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities.
- Conditions
- Osteoarthritis, Hip, Cardiovascular Diseases, Bone Cement Implantation Syndrome, Kidney Diseases
- Trial name
- PRINCIPAL (NCT06323018)
- Testing
- Remote Ischemic Preconditioning
- Where
- Estonia
- Volunteers
- 200 people
- Sponsor
- University of Tartu
Heart Valve Diseases
Effect of Remote Ischemia Preconditioning on Myocardial Injury in Patients Undergoing Heart Valve Surgery
Remote ischaemic preconditioning has shown its cardiac protective effect during heart surgery including coronary artery bypass graft surgery, congenital heart disease and aneurysm.
- Trial name
- NCT01175681
- Testing
- remote ischaemic preconditioning
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Sun Yat-sen University
Heart Valve Surgery, Acute Kidney Injury
Effects of Remote Ischemic Preconditioning at Different Time Phases in Patients Undergoing Heart Valve Surgery
Patients undergoing heart valve surgery require cardiopulmonary bypass, a procedure that can lead to a temporary reduction in blood flow to major organs and subsequent ischemia-reperfusion injury, thereby triggering postoperative…
- Trial name
- NCT07888634
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Fujian Medical University Union Hospital