Clinical trials: Remote Ischemic Preconditioning
HF - Heart Failure
Acute Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Vascular Parameters in Patients With Suspected Heart Failure With Preserved Ejection Fraction
The PIRIC-FEp study will be a randomized clinical trial in sedentary patients with suspected heart failure with preserved ejection fraction.
- Trial name
- PIRIC-FEp (NCT07365501)
- Testing
- remote ischemic preconditioning
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- University of Castilla-La Mancha
Congenital Heart Disease, Cardiopulmonary Bypass
Seattle Cardiorenal Remote Ischemic Preconditioning Trial
Remote Ischemic Preconditioning (RIPC) is a treatment that may be associated with improved outcomes after cardiac surgery. It can be elicited noninvasively by using a tourniquet to elicit transient ischemia over a lower…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Myocardial Injury, Acute Kidney Injury
- Trial name
- SCRIPT (NCT01260259)
- Testing
- RIPC, Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Aortic Dissection Type A
Remote Ischemic Preconditioning for Aute Type A Aortic Dissection Surgery
The goal of this clinical trial is to learn if a technique called remote ischemic preconditioning (RIPC) helps protect organs during emergency surgery for acute type A aortic dissection (ATAAD).
- Trial name
- NCT07383909
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- 16 sites in China
- Volunteers
- 1,312 people
- Sponsor
- Fujian Medical University
Myocardial Injury, Mortality
Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart-Study)
The purpose of this study is to evaluate the effects of Remote Ischaemic Preconditioning on perioperative ischaemic injury in patients undergoing cardiac surgery compared to control intervention.
- Trial name
- NCT01067703
- Testing
- Remote Ischemic Preconditioning
- Where
- 10 sites in Germany
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Schleswig-Holstein
Acute Kidney Insufficiency, Acute Renal Insufficiency
The Influence of Remote Ischemic Preconditioning on Acute Kidney Injury After Cardiac Surgery
Acute kidney injury is associated with cardiopulmonary bypass during heart surgery and its pathogenesis is similar to that of ischemia-reperfusion injury.
- Conditions
- Acute Kidney Insufficiency, Acute Renal Insufficiency, Acute Kidney Injury, Ischemic Preconditioning
- Trial name
- NCT00821522
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Robert Kramer, MD
Ischemic Stroke, Remote Ischaemic Preconditioning
Effect of Remote Ischemic Preconditioning on Early Neurological Deterioration in Acute Perforating Artery Infarction
This study aims to conduct a prospective, randomized, double-blind, multicenter, parallel-controlled, group-sequential trialto scientifically evaluate the safety and efficacy of remote ischemic preconditioning (RIC) in preventing…
- Trial name
- RIC-END (NCT07237542)
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 910 people
- Sponsor
- Jinling Hospital, China
Transplant Dysfunction
Remote Ischaemic Preconditioning in Transplantation (RIPTRANS)
Remote ischemic preconditioning (RIPC) is a concept where remotely induced ischemia produces protection against ischemia-reperfusion injury in a remote organ.
- Trial name
- NCT03855722
- Testing
- RIPC
- Where
- Finland
- Volunteers
- 496 people
- Sponsor
- Helsinki University Central Hospital
Peripheral Arterial Diseases
Effects of Remote Ischemic Preconditioning on Moderate PVD Patients A Pilot Randomized Control Trial
Remote ischemic Preconditioning (RIPC) is a phenomena first observed in cardio-thoracic patients in which exposing the limbs for periods of short intermittent ischemia produces protective effect on heart muscle.
- Trial name
- RIPC-PVD (NCT02273232)
- Testing
- Remote Ischemic Preconditioning, Supervised Exercise, Standard Care
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- National University of Ireland, Galway, Ireland
Lung Neoplasms
Effect of Remote Ischemic Preconditioning on Lung Injury After Pulmonary Resection
The purpose of this study is to determine whether ischemic preconditioning reduces lung injury in patients undergoing pulmonary resection.
- Trial name
- NCT01307085
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Cai Li
Effectivity of RIPC in Outcomes of TAVI Procedure
Cardioprotective Effect of RIPC in Patients Undergoing TAVI
We aim to investigate whether RIPC (remote ischemic preconditioning) is effective in the TAVI setting to reduce post-procedural myocardial damage and improve patient outcome.
- Trial name
- CARE-TAVI (NCT02283398)
- Testing
- without RIPC, RIPC
- Where
- 3 sites in Germany
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Pressure; Brachial Plexus
The Effect of Remote Ischemic Preconditioning (RIPC) on Blood Pressure and Its Vascular Protection Effect
The purpose of this study is to determine the effect of remote ischemic preconditioning (RIPC) on blood pressure and its vascular protection effect among Chinese young healthy adults and primary hypertensive patients stage I.
- Trial name
- NCT02414997
- Testing
- RIPC
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Liver Surgery, Remote Ischaemic Preconditioning
Lactate Clearance After RIPC in Liver Resection
The primary aim of the study is the evaluation of the efficacy of remote ischemic preconditioning (RIPC) in terms of increase of the clearance of lactates 4 hours after the end of the hepatic resection.
- Trial name
- ARAGON (NCT05594641)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Exercise
Ischemic Preconditioning in Endurance Athletes
The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.
- Trial name
- NCT01774461
- Testing
- Remote ischemic preconditioning
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Acute Mountain Sickness
Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide
The primary objective of the study will be to determine whether rapid remote limb ischemic preconditioning (RIPC) combined with acetazolamide can further reduce the incidence of acute mountain sickness (AMS) during the 6-hour…
- Trial name
- NCT05023941
- Testing
- Acetazolamide, Doctormate® (twice daily for 6 days), Doctormate® (forth daily for 3 days)
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Ji Xunming,MD,PhD
Ischemic Preconditioning, Acute Kidney Injury
Remote Ischemic Preconditioning During Lower Limb Revascularization
The aim of this study is to evaluate the role of remote ischemic preconditioning (RIPC) in preventing acute kidney injury after lower limb revascularization.
- Conditions
- Ischemic Preconditioning, Acute Kidney Injury, Limb Ischemia
- Trial name
- NCT04016857
- Testing
- RIPC, Control
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Messina
Ischaemic Reperfusion Injury
Remote Ischaemic Preconditioning in Children Undergoing Cardiac Surgery
Surgical correction of congenital heart defects in children requires the utilization of cardiopulmonary bypass, a technique that temporarily substitutes heart and lung functions during surgery.
- Trial name
- NCT01680601
- Testing
- Remote ischaemic preconditioning (RIPC)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- NHS Greater Glasgow and Clyde
Acute Cholecystitis, Endothelial Dysfunction
Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery
This study examines if remote ischemic preconditioning in patients undergoing minor acute abdominal surgery (laparoscopic cholecystitis due to acute cholecystitis) is associated with a modulation of endothelial dysfunction.
- Trial name
- PUMAS (NCT04156711)
- Testing
- Remote Ischemic Preconditioning (RIPC)
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Aortic Valve Disease, Myocardial Ischemia
Remote Ischemic Preconditioning in Patients Undergoing Isolated Aortic Valve Replacement Surgery
The goal is to investigate the efficacy, safety and possible neuro- and cardioprotective effects of remote ischemic preconditioning (RIPC) in adult cardiac patients undergoing isolated aortic valve replacement surgery with a…
- Trial name
- NCT02694016
- Testing
- Remote ischemic preconditioning
- Where
- Finland
- Volunteers
- 4 people
- Sponsor
- Oulu University Hospital
Myocardial Injury, Cardiac Surgery
Effect of Cyclosporine and Remote Ischemic Preconditioning in Reperfusion Ischemia Injury on Tetralogy Fallot Patients With Correction Surgery
The study aimed to evaluate the combined effects of cyclosporine and remote ischemic preconditioning on MDA, calcium cytosol concentration, and mitochondrial edema in tetralogy Fallot patients undergoing corrective surgery.
- Trial name
- NCT05691764
- Testing
- Cyclosporin, remote ischemic preconditioning
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Hypertension, Vascular Diseases
The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
The purpose of this study is to assess whether remote ischaemic conditioning, applied chronically, improves vascular health in older adults
- Trial name
- RIPCo (NCT05971407)
- Testing
- Remote Ischaemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham