Clinical trials: Remote Ischemic Preconditioning
Ischemic Reperfusion Injury
Single-cycle Remote Ischemic Preconditioning and Postconditioning for Prevention of Contrast-Induced Nephropathy
This trial is a 2 x 2 factorial design, double-blinded, randomized controlled trial to evaluate efficacy and safety of remote ischemic preconditioning and postconditioning for prevention of contrast-induced acute kidney injury in…
- Trial name
- NCT02729155
- Testing
- RIPre, RIPost
- Where
- Thailand
- Volunteers
- 596 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Carotid Artery Stenosis
Effect of Remote Ischemic Preconditioning on Cerebral Circulation Time in Patients With Severe Carotid Artery Stenosis (RIP-CCT)
Cerebral circulation time in patients with severe carotid artery stenosis was found to be associated with hyperperfusion syndrome. Remote ischemic preconditioning can change the ability of cerebral autoregulation.
- Trial name
- NCT05451030
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 122 people
- Sponsor
- General Hospital of Shenyang Military Region
Angina Pectoris, Myocardial Infarction
The Effect of Remote Ischemic Preconditioning on Major Organ Function in Patients With Coronary Artery Disease Undergoing Orthopedic Surgery
The investigators attempt to investigate the organ protective effect of remote ischemic conditioning in patients undergoing non-cardiac surgery with history of ischemic heart disease.
- Trial name
- RIPC-Angina (NCT02808936)
- Testing
- Remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Ischemia-reperfusion (IR) Injury
Clinical and Genomic Responses to Open Heart Surgery
This study will be the first large scale randomized study of remote ischemic preconditioning (RIPC) ever performed and will define the role of this novel therapy as a clinical tool.
- Trial name
- NCT00650507
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- The Hospital for Sick Children
Heart Valve Disease
Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass
The purpose of this study is to study the effect of remote ischemic preconditioning on acute kidney injury in patients undergoing heart valve replacement surgery with cardiopulmonary bypass.
- Trial name
- NCT01023152
- Testing
- Automated cuff-inflator
- Volunteers
- 74 people
- Sponsor
- Yonsei University
Ischemic Preconditioning
Remote Ischemic Preconditioning of Dynamic Cerebral Autoregulation in Healthy Adults
The purpose of this study is to determine the impact of remote ischemic preconditioning on dynamic cerebral autoregulation and related hematology indexes in healthy adults.
- Trial name
- RIPCA (NCT02965547)
- Testing
- Remote ischemic conditioning equipment, Intravenous blood collection, dCA measurement
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yi Yang
Coronary Artery Disease, Diabetes Mellitus
The Effect of Remote Ischemic Preconditioning on Diastolic Function in Coronary Artery Bypass Surgery Between Diabetic and Non-Diabetic Patients
This randomized controlled study aims to evaluate the effects of Remote Ischemic Preconditioning (RIPC) on diastolic function in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Diastolic Function
- Trial name
- NCT06841757
- Testing
- Remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alzahraa Khalil Marie
Ischaemic Heart Diseases
The Effect of Ischaemic-Reperfusion and Ischaemic Preconditioning on the Endogenous Fibrinolysis in Man
Heart attacks are usually caused by a blood clot blocking an artery supplying blood to the heart. Current treatments are designed at relieving this blockage as quickly as possible to minimise damage to the heart muscle.
- Trial name
- NCT00789243
- Testing
- Forearm vascular study
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Acute Kidney Injury
Remote Ischemic Preconditioning and Risk of Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Stent Implantation
This single-center, randomized controlled trial is to investigate the impact of remote ischemic preconditioning (RIPC) on the risk contrast-induced acute kidney injury and its long-term impact on renal function for patients with…
- Trial name
- REPAIR (NCT01827891)
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Beijing Anzhen Hospital
Myocardial Infarction
Long-term Remote Ischemic Preconditioning Improve Long-term Prognosis of Acute Myocardial Infarction Patients Without Emergency Reperfusion Therapy
Patients with acute myocardial infarction (AMI) are in critical condition especially without emergency reperfusion therapy. For example, heart failure, heart rupture, malignant arrhythmia are in high level.
- Trial name
- NCT02843464
- Testing
- reported remote ischemic preconditioning (RIPC)
- Volunteers
- 220 people
- Sponsor
- Xuanwu Hospital, Beijing
Myocardial Ischemia, Inflammatory Response
Remote Ischemic Preconditioning and Postoperative Myocardial Ischemia
High-risk abdominal surgery is frequently complicated by postoperative complications, such as sepsis, pneumonia or anastomotic dehiscence.
- Trial name
- MICOLON2 (NCT03460938)
- Testing
- Remote ischemic preconditioning
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- St. Antonius Hospital
Atrial Fibrillation
Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Recent studies indicate that remote ischemic conditioning can protect the heart and other organs during cardiac surgery. The investigators aim to investigate whether such a stimulus can reduce the incidence of atrial fibrillation…
- Trial name
- RICO (NCT01107184)
- Testing
- Remote ischemic conditioning
- Where
- Netherlands
- Volunteers
- 191 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Renal Function, Renal Injury
Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality.
- Trial name
- RenPRO-TAVI (NCT01925235)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Ischemia-Reperfusion Injury, Free Flap
Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction
This prospective randomized clinical study investigates the effects of Remote Ischemic Conditioning (RIC) on tissue perfusion and ischemia-reperfusion injury in patients undergoing free flap reconstruction in reconstructive…
- Conditions
- Ischemia-Reperfusion Injury, Free Flap, Conditioning Therapy
- Trial name
- RIPC (NCT07487220)
- Testing
- Remote ischemic preconditiong
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- Ruhr University of Bochum
Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast Nephropathy
Contrast-medium induced nephropathy (CIN) is a frequent and devastating complication of coronary angiography, occurring in 10-50% of cases.
- Trial name
- RIPC-CIN (NCT02674451)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Johns Hopkins University
Vascular Function
Effects of SIT Combined with Remote Ischemic Preconditioning on Vascular Function in Young Women with Masked Obesity
Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.
- Trial name
- NCT06664281
- Testing
- SIT, SIT combined RIPC
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Stroke
Protective Effects of Remote Limb Ischemic Preconditioning on Acute Cerebral Infarction
Stroke is one of the three leading causes of human death, and a major cause of adult disability. Our pre-clinical studies confirmed that ischemic preconditioning can prevent cerebral infarction.
- Trial name
- NCT01672515
- Testing
- RIPC group, Control group
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Myocardial Infarction
Effect of Propofol on Cardioprotective Role of Remote Ischemic Preconditioning (RIPC)
This study involves research using human subjects (cardiac surgical patients) to evaluate the effect of remote ischemic preconditioning (RIPC) on cardioprotective outcomes.
- Trial name
- NCT02932722
- Testing
- Control, Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Ischemic Stroke, Cerebral Small Vessel Disease
Remote Preconditioning Over Time To Empower Cerebral Tissue
Previous studies in animals and humans has shown that brief periods of reduced blood flow to one organ or tissue in the body can help protect other tissues from subsequent injury caused by reduced blood flow such as a stroke.
- Conditions
- Ischemic Stroke, Cerebral Small Vessel Disease, Cognitive Decline
- Trial name
- REM-PROTECT (NCT02169739)
- Testing
- Ischemic Preconditioning
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Myocardium; Injury, Cardiac Surgical Procedures
The Effect of Remote Ischemic Preconditioning in the Cardiac Surgery
Perioperative myocardial injury is a serious complication of cardiac surgery. This complication increases both mortality and morbidity of cardiac surgery.
- Trial name
- RIPC (NCT00997217)
- Testing
- remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Seoul National University Hospital