Clinical trials: Remote Ischemic Preconditioning
Autoimmune Diseases, Infection
the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia
In a wide range of auto-inflammatory and infectious diseases attenuation of the immune response could be beneficial. Remote ischemic preconditioning (RIPC) has been identified as a means of protecting patients undergoing cardiac…
- Trial name
- RISPENDO (NCT02602977)
- Testing
- Multiple-dose Remote Ischemic Preconditioning, Single-dose Remote Ischemic Preconditioning, LPS infusion
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Acute Myocardial Infarction
Effects of Long-term Remote Ischemic Preconditioning on Clinical Outcome in Patients With Acute Myocardial Infarction
At present, there are 290 million cardiovascular patients in China, including 11 million patients with coronary heart disease. Remote ischemic preconditioning(RIPC) may play an effective endogenous cardiac protection.This study…
- Trial name
- L-RICP-AMI (NCT07181356)
- Testing
- RIPerC, RIPC
- Where
- China
- Volunteers
- 2,146 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Hypertension
Long-term of Remote Ischemic Preconditioning and Mindfulness in Patients With Mild Hypertension
According to the latest survey data of China hypertension annual meeting, there are about 300 million patients with hypertension in China, with 10 million new cases of hypertension each year, and there is an obvious trend of…
- Trial name
- NCT04753840
- Testing
- CRIC, MFT
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Perioperative Myocardial Injury
Perioperative Reduction of Inapparent Myocardial Injury
Recent data suggests that subclinical myocardial injury occurs in patients undergoing major abdominal surgery, and the degree of damage is proportionally linked to morbidity and mortality in the short and medium terms.
- Trial name
- PRIME (NCT01850927)
- Testing
- Remote ischaemic preconditioning, Control
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- London Surgical Research Group
Myocardial Infarction, Acute
Long-term Remote Ischemic Preconditioning Improve the Prognosis of Myocardial Infarction Patients With Emergency Reperfusion Therapy
Patients with acute myocardial infarction (AMI) are in critical condition. When primary percutaneous coronary intervention (PCI) was performing, no-reflow, reperfusion injury，heart failure, heart rupture, malignant arrhythmia…
- Trial name
- NCT03018873
- Testing
- remote ischemic preconditioning （RIPC）
- Volunteers
- 400 people
- Sponsor
- Xuanwu Hospital, Beijing
Aortic Valve Stenosis
Protection by Remote Ischemic Preconditioning During Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) has rapidly been adopted into clinical practice, but concerns have been raised regarding periprocedural complications like e.g. myocardial injury, stroke or acute kidney injury.
- Trial name
- NCT02080299
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital, Essen
Renal Cell Carcinoma
Effect of Ketorolac and Remote Ischemic Preconditioning on Renal Ischemia-reperfusion Injury in Patients Undergoing Partial Nephrectomy
Partial nephrectomy is a widely accepted alternative to radical nephrectomy in patients with clinically localized, unilateral renal cell carcinoma and a normal contralateral kidney.
- Trial name
- NCT01836406
- Testing
- Ketorolac tromethamine and remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Yonsei University
HF - Heart Failure
Effect of Nurse-assessed Remote Ischemic Preconditioning on Improving Exercise Capacity, Endothelial Function, and Arterial Stiffness in Patients With Heart Failure With Preserved Ejection Fraction
The PIRIC-FEp study will be a randomized clinical trial in sedentary patients with heart failure and stable preserved ejection fraction.
- Trial name
- PIRIC-FEp Stud (NCT07024810)
- Testing
- remote ischemic preconditioning
- Volunteers
- 48 people
- Sponsor
- University of Castilla-La Mancha
Hepatocellular Cancer
Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery
Liver resection has improved health outcomes in patients with hepatocellular carcinoma (HCC) in Singapore and worldwide. However, due to acute ischaemia/reperfusion injury (IRI) to the liver at the time of surgery, patients still…
- Trial name
- NCT03594929
- Testing
- Active RIC
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Perioperative/Postoperative Complications
Remote Ischemic Preconditioning Before Abdominal Surgery
Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%. Ischemic preconditioning may have a protective effect.
- Trial name
- NCT01340742
- Testing
- Remote Ischemic Pre-conditioning, Control
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Neuronal Injury
Remote Ischemic Preconditioning and Postoperative Neuronal Injury
The SHIELD trial is a single-center, randomized, controlled, parallel-group, single-blinded clinical trial investigating whether performing RIPC one day before surgery-compared to not performing RIPC-reduces postoperative…
- Trial name
- SHIELD (NCT07420153)
- Testing
- Remote ischemic preconditioning, Routine care
- Where
- Germany
- Volunteers
- 216 people
- Sponsor
- University of Hamburg-Eppendorf
Cerebral Aneurysm
Remote Ischemic Preconditioning for Intracranial Aneurysm Treatment
The RIPAT study is a prospective, randomized, double-blind study organized by the neurovascular group of the Clinical Department of Neurosurgery of Innsbruck Medical University, Innsbruck, Austria.
- Trial name
- RIPAT (NCT02162654)
- Testing
- Remote ischemic preconditioning
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University Innsbruck
Renal Cell Carcinoma
Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy
Partial Nephrectomy has become the standard treatment in patients with tumours <7cm (T1). Even though this is a nephron sparing surgery, there is still potential for acute kidney injury, due to ischemia during the surgery.
- Trial name
- NCT01771003
- Testing
- CellAegis' autoRIC™ Device
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University Health Network, Toronto
Remote Ischaemic Preconditioning, Contrast Induced Nephropathy
Use of Remote Ischaemic Preconditioning in the Prevention of Contrast Induced Nephropathy
With an increasingly ageing population the incidence of peripheral arterial disease (PAD) is rising. With approximately one quarter of all PAD patients ultimately progressing to Critical Limb Ischaemia (CLI), increased demands…
- Trial name
- NCT02516072
- Testing
- RIPC
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital
Cervical Compression Myelopathy, Ischemia
Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery
The purpose of this study is to assess whether a large clinical trial testing the effect of RIPC on neurologic outcome in patients undergoing elective cervical decompression surge is warranted.
- Conditions
- Cervical Compression Myelopathy, Ischemia, Reperfusion Injury, Spinal Cord Injury
- Trial name
- NCT00778323
- Testing
- limb remote ischemic preconditioning (LRIPC)
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Xijing Hospital
Laparoscopic Colorectal Surgery
Limb Remote Ischemic Preconditioning for Heart and Intestinal Protection During Laparoscopic Colorectal Surgery
Remote ischaemic preconditioning may confer the cytoprotection in critical organs. The investigators hypothesized that limb remote ischemic preconditioning (RIPC) would reduce heart and gastrointestinal function injury in…
- Trial name
- NCT01832337
- Testing
- Limb remote ischemic preconditioning (LRIP)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fei Li
Coronary Artery Bypass Graft Triple Vessel, Apoptotic DNA Damage
Remote Ischemic Preconditioning of Human Myocardium
The investigators aim to definitively show if human myocardium can be remotely preconditioned. In the writings there are no experiments that would prove that the remote preconditioning protocol effects on the higher protection of…
- Trial name
- NCT01994707
- Testing
- Remote ischemic preconditioning
- Where
- Poland
- Volunteers
- 134 people
- Sponsor
- Medical University of Silesia
Cardiac Function and Preconditioning
Effects of Remote Cardiac Ischemic Preconditioning
A heart attack occurs when blood flow is disrupted to the heart and is related to both the blockage and flow restoration (reperfusion injury).
- Trial name
- NCT06390358
- Testing
- Tefillin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jack Rubinstein
Kidney Transplantation, Delayed Graft Function
Context - Remote Ischemic Conditioning in Renal Transplantation - Effect on Immediate and Extended Kidney Graft Function
The purpose of this study is to determine whether remote ischemic conditioning can improve the outcome after renal transplantation with deceased donor.
- Conditions
- Kidney Transplantation, Delayed Graft Function, Acute Kidney Injury, Glomerular Filtration Rate
- Trial name
- Context (NCT01395719)
- Testing
- Remote ischemic conditioning
- Where
- 4 sites in Denmark, Netherlands and 1 more
- Volunteers
- 220 people
- Sponsor
- University of Aarhus
Patients With Elective Aortic Valve Replacement
Remote Ischemic Preconditioning Induces Myocardial RISK Signaling Pathway in Patients Undergoing Valvular Heart Surgery
The aim of this study is to investigate whether RIPC protects the heart against ischemia reperfusion injury on the concentrically hypertrophied myocardium
- Trial name
- NCT01946087
- Testing
- Remote ischemic preconditioning at left upper arm, Control group
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University