Clinical trials: Renal Dialysis
End Stage Kidney Disease (ESRD), Hemodialysis
Hand Reflexology for Fatigue and Anxiety in Hemodialysis Patients
This randomized controlled trial evaluates the efficacy of hand reflexology massage (HRM) in reducing fatigue and anxiety among adult patients receiving maintenance hemodialysis.
- Conditions
- End Stage Kidney Disease (ESRD), Hemodialysis, Anxiety, Fatigue
- Trial name
- NCT07253831
- Testing
- Hand Reflexology Massage, Standard
- Where
- Iraq
- Volunteers
- 70 people
- Sponsor
- Kufa University
Acute Renal Failure
Influence Continuous Veno-venous Hemodialysis the Autoregulation
The aim of the study is to characterize the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
- Trial name
- dARICUCVVH (NCT01376531)
- Testing
- continuous veno-venous hemodialysis
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Johannes Gutenberg University Mainz
Kidney Disease, Chronic
Oral Findings in a Group of Egyptian Pediatric Patients at Endstage Renal Disease
In Egypt, the prevalence of end stage renal disease in pediatric population has never been estimated on a national scale. The patients at end stage renal disease encounter oral and dental problems that emphasize regular and…
- Trial name
- NCT03590067
- Testing
- Questionnaire
- Volunteers
- 150 people
- Sponsor
- Cairo University
Cardiovascular Diseases
Vitamin K1 to Slow Progression of Vascular Calcification in HD Patients
Patients on hemodialysis (HD) exhibit an immensely increased cardiovascular mortality associated with extensive vascular calcification (VC).
- Trial name
- VitaVasK (NCT01742273)
- Testing
- Vitamin K1
- Where
- 13 sites in Belgium, Germany and 1 more
- Volunteers
- 63 people
- Sponsor
- RWTH Aachen University
Chronic Kidney Disease, Dialysis
A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia
This is a phase III multi-centre study in three periods: the first period is a phosphate binder washout for 4 weeks, the second period is an open-label, flexible dose titration, the third period is a placebo-controlled withdrawal…
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00506441
- Testing
- MCI-196
- Where
- 39 sites in United States, Puerto Rico
- Volunteers
- 245 people
- Sponsor
- Tanabe Pharma Corporation
End Stage Renal Disease
Safety and Efficacy Study of the Effect of Etanercept in Hemodialysis Patients
Etanercept is a novel anti-inflammatory agent currently used in patients with rheumatoid arthritis. We are examining whether Etanercept is effective in improving the nutritional status of hemodialysis patients as a consequence of…
- Trial name
- NCT00293202
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kaysen, George A., M.D., Ph.D.
End-Stage Renal Disease; Hemodialysis
Nurse-Led Nutrition and Exercise Program for Hemodialysis Patients
This randomized controlled trial aims to evaluate the effectiveness of a nurse-led integrated nutrition and exercise intervention on improving health-related quality of life among hemodialysis patients.
- Trial name
- HD-NEX (NCT07535957)
- Testing
- Nurse-Led Integrated Nutrition and Exercise Program, Usual Hemodialysis Care
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Misan
Chronic Renal Failure, Hemodialysis
The Effect of CoQ10 Administration on Hemodialysis Patients
The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.
- Trial name
- NCT00307996
- Testing
- Coenzyme Q10 (drug)
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- University of Shizuoka
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis
This 6 month study will assess an investigational medication for patients on dialysis with secondary hyperparathyroidism. The study will look at the effects on parathyroid hormone, calcium and phosphorus levels.
- Trial name
- NCT00042653
- Testing
- AMG 073
- Volunteers
- 380 people
- Sponsor
- Amgen
Coronary Calcification, Vascular Calcification
Intravenous Sodium Thiosulfate on Coronary Calcification in Patients on Hemodialysis
The present study will examine the treatment effect of sodium thiosulfate on coronary calcification in patients on hemodialysis.
- Trial name
- NCT00720772
- Testing
- 25% intravenous (IV) sodium thiosulfate
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Ramathibodi Hospital
Hemodialysis Complication, Hemodynamic Instability
MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)
This proposal will measure the effects of mannitol administration versus placebo in hypotensive-prone, adult, maintenance hemodialysis patients with respect to changes in patient symptoms and blood pressure stability.
- Trial name
- NCT04428372
- Testing
- Mannitol, 0.9% saline
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Brigham and Women's Hospital
Arterial Hypertension, Hemodialysis
Mechanisms and Phenotypes of Hypertension in Patients in Chronic Hemodialysis
The goal of this study is to evaluate interdialytic blood pressure changes of the patients in chronic hemodialysis. The main question to be answered is: What is the relative importance of weight gain, the renin angiotensin…
- Trial name
- NCT06764277
- Testing
- There will be no intervention
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Bernardo Rodríguez Iturbe
Inflammatory Status, P-cresol
HFR Cartridge and Inflammation
A major limitation of standard hemodialysis is that it does not clear the plasma from interleukin-6 (IL-6) and p-cresol, two uremic toxins responsible for the high cardiovascular risk in end stage renal disease (ESRD).
- Trial name
- HFR (NCT01865773)
- Testing
- HFR dialysis
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Federico II University
Haemodialysis, End Stage Renal Disease on Dialysis
SASH: Sodium Accumulation Study In Haemodialysis
Haemodialysis (HD) sustains life in patients with end-stage kidney disease (ESKD) but is associated with a marked increase in incidence of cardiovascular disease (CVD) and high annual mortality rates.
- Trial name
- SASH (NCT05128188)
- Testing
- No intervention will be given in this study
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Pruritis
Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients
The purpose of this research study is to evaluate the efficacy of SARNA Sensitive Lotion in the treatment of uremic pruritus in adult hemodialysis patients in a double-blind Controlled comparative trial.
- Trial name
- NCT00693654
- Testing
- Sarna, Cetaphil
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University
Dialysis, Cardiovascular Disease
Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid
Patients with kidney failure on hemodialysis have an extremely high rate of cardiovascular disease including atherosclerotic cardiovascular disease.
- Conditions
- Dialysis, Cardiovascular Disease, Atherosclerosis, Inflammation
- Trial name
- NCT01159054
- Testing
- Extended Release Nicotinic Acid (Niaspan)
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Brigham and Women's Hospital
Heart Failure, Kidney Disease
Neck-Worn Monitoring Sensor for - A Study for Monitoring Subjects With Fluid-Management Issues During Dialysis
The study has two objectives based on the intended-use measurements and populations described above. The first objective is to show that relative changes in impedance as measured by the test device (ΔSFI) are strongly correlated…
- Trial name
- NCT02140905
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Baxter Healthcare Corporation
Chronic Kidney Disease, Peritoneal Dialysis Access
Improving Outcomes in Peritoneal Dialysis
The objective is to understand the best way to place Peritoneal Dialysis (PD) catheters, and the best way to collect data regarding their function in England, Wales and Northern Ireland.
- Trial name
- NCT02207751
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Renal Dialysis, Integrative Medicine
Integrative HD Vascular Access Assessment
The aim of this two-year study is to explore the relationship among function of HVA, nail-fold capillaries and TCM constitutions based on hybridizing data mining techniques.
- Conditions
- Renal Dialysis, Integrative Medicine, Hemodialysis Access Failure
- Trial name
- NCT03140345
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Peri-dialytic Cardiac Rhythms, Intradialytic Hypotension
Trial of Variable Dialysate Bicarbonate
QTc prolongation and premature ventricular contractions (PVCs) are common in hemodialysis (HD) patients and are associated with sudden cardiac death.
- Conditions
- Peri-dialytic Cardiac Rhythms, Intradialytic Hypotension, Electrolyte Changes, pH Changes
- Trial name
- NCT05814146
- Testing
- Dialysate bicarbonate concentration, Dialysate bicarbonate concentration - telemetry monitoring
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Brigham and Women's Hospital