Clinical trials: Renal Function After Partial Nephrectomy
Renal Cell Cancer
The Value of a Convolutional Neural Network-Based Renal Artery Perfusion Model in Predicting Renal Function After Partial Nephrectomy: A Prospective Study
The goal of this observational study is to develop a CNN-based machine module to predict postoperative fractional renal function in people who are proposed to undergo partial nephrectomy.
- Trial name
- NCT06751498
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Shao Pengfei
Renal Cell Carcinoma, Renal Function Abnormal
The Cold Ischemia Robot-assisted Partial Nephrectomy
To establish evidence that cold ischemia, achieved through the use of ice slush, can improve the recovery from ischemia on the operated kidney in patients undergoing robot-assisted partial nephrectomy.
- Trial name
- NCT07326280
- Testing
- Cold ischemia robot-assisted partial nephrectomy, Warm ischemia robot-assisted partial nephrectomy
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Sun Yat-sen University
Renal Cell Carcinoma
Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy
Preserving kidney function during removal of a kidney tumor is becoming increasingly important as rates of chronic kidney disease increase.
- Trial name
- NCT02131376
- Testing
- Non-renorrhaphy, Renorrhaphy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
Kidney Neoplasms
Assessment of Oncological and Functional Outcomes After Robot Assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
Currently, partial nephrectomy (PN) is considered as the gold standard treatment modality for small renal masses. In this setting, robot-assisted and conventional laparoscopic approaches are gaining more consensus every day.
- Trial name
- NCT02924922
- Testing
- Laparoscopic partial nephrectomy, Robot assisted partial nephrectomy, Conventional laparoscopic instruments
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- Luzerner Kantonsspital
Ischemia Reperfusion Injury
Pneumoperitoneum Preconditioning for the Prevention of Renal Function After Laparoscopic Partial Nephrectomy
The present study is designed to investigate the short-term and long-term renoprotective role of pneumoperitoneum preconditioning in patients undergoing laparoscopic partial nephrectomy.
- Trial name
- NCT03822338
- Testing
- Pneumoperitoneum preconditioning
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Kidney Neoplasms / Surgery, Glomerular Filtration Rate
The Study on the Effectiveness of [68Ga]Ga-HBED-CC-DiAsp PET/CT in Calculating GFR and Predicting Residual Renal Function After Partial Nephrectomy
In subjects with different levels of renal function and no history of renal tumors, GFR is measured using [68Ga]Ga-HBED-CC-DiAsp PET/CT, the Gates method, and the 99mTc-DTPA dual plasma method.
- Conditions
- Kidney Neoplasms / Surgery, Glomerular Filtration Rate, Positron-Emission Tomography(PET)
- Trial name
- NCT06973798
- Testing
- GFR will be measured using three methods at two weeks before surgery and four ± one week after surgery, GFR will be measured using three methods: [68Ga]Ga-HBED-CC-DiAsp PET/CT, the Gates method, and the dual plasma sampling method with 99mTc-DTPA.
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luo Yaping
Renal Cell Carcinoma, Kidney Neoplasms
Multimodal Prediction of Postoperative Prognosis After Partial Nephrectomy for Endophytic Renal Cell Carcinoma
This retrospective observational cohort study aims to develop and externally validate an imaging-clinical multimodal fusion model for predicting postoperative prognosis in patients with endophytic renal cell carcinoma undergoing…
- Conditions
- Renal Cell Carcinoma, Kidney Neoplasms, Endophytic Renal Tumor, Postoperative Renal Function
- Trial name
- PN-ProMM (NCT07697417)
- Testing
- Imaging-clinical multimodal prognostic modeling
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Tianjin Medical University Second Hospital
Renal Cell Carcinoma (RCC), Renal Function Abnormal
Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
- Trial name
- NCT07497958
- Testing
- Ischemic preconditioning, NO ischemic preconditioning
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Sun Yat-sen University
Renal Cell Carcinoma (RCC)
Computed Tomography Radiomics-Derived Nomogram for Predicting Early Renal Function Decline After Partial Nephrectomy in Renal Cell Carcinoma: A Multicenter Development/Validation Study
The goal of this observational study is to explore the relationship between CT-based radiomics and postoperative renal function changes in patients with localized renal cell carcinoma (RCC) undergoing partial nephrectomy (PN).
- Trial name
- NCT07117786
- Testing
- CT Contrast, Computed Tomography
- Volunteers
- 1,437 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Partial Nephrectomy, Kidney Cancer
Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy
After partial nephrectomy, kidney function decreases by about 10% overall and by about 20% in the operated kidney. This is primarily due to the loss of healthy parenchymal volume during resection of the tumor.
- Conditions
- Partial Nephrectomy, Kidney Cancer, Renal Function Aggravated
- Trial name
- NCT03323021
- Testing
- Dehydrated human amnion/chorion membrane, Standard of Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- MiMedx Group, Inc.
Renal Cell Carcinoma
The Evaluation of Functional Parenchymal Volume and Split Renal Function Before and After Partial Nephrectomy
The study aims to compare pre- and postoperative 3D renal function results of patients who underwent on-clamp and off-clamp partial nephrectomy.
- Trial name
- NCT04798963
- Testing
- On-clamp partial nephrectomy, Off-clamp partial nephrectomy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Nephrectomy, Renal Cell Cancer
Contrast-enhanced Ultrasound and Super-resolution Imaging Predict Renal Function Outcome After Nephrectomy
The goal of this prospective cohort study is to evaluate the predictive value of Contrast-Enhanced Ultrasound (CEUS) and Super-Resolution Imaging (SRI) technologies regarding renal function outcomes in patients with renal cell…
- Conditions
- Nephrectomy, Renal Cell Cancer, AKI - Acute Kidney Injury
- Trial name
- NCT07294859
- Where
- China
- Volunteers
- 285 people
- Sponsor
- Jinling Hospital, China
Renal Function After Partial Nephrectomy
PaNeX: Partial Nephrectomy Under Xenon
Purpose of this study is to determine whether Xenon - as compared to Isoflurane - shows a nephroprotection after partial nephrectomy.
- Trial name
- PaNeX (NCT01839084)
- Testing
- Xenon, Isoflurane
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- RWTH Aachen University
Renal Cell Carcinoma
Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy
This study is designed to investigate a novel approach to offer more ESRD participants the benefits associated with renal transplantation by increasing the supply of available allografts
- Trial name
- NCT05725421
- Testing
- Donor Radical and Partial Nephrectomy, Kidney Transplantation, Laparoscopic Radical Nephrectomy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center