Clinical trials: Renal Injury, Acute
Obstructive Sleep Apnea, Acute Kidney Failure
Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function
Obstructive sleep apnea (OSA) is a frequently underdiagnosed condition that has emerged as an increasing medical problem with important social and financial implications worldwide.
- Conditions
- Obstructive Sleep Apnea, Acute Kidney Failure, Chronic Kidney Disease
- Trial name
- OSA-AKI (NCT00947479)
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
Acute Kidney Injury, Liver Transplant; Complications
Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients
The goal of this clinical trial is to evaluate the effect of intraoperative terlipressin on the incidence of early postoperative acute kidney injury in deceased doner liver transplantation.
- Trial name
- NCT06108362
- Testing
- Terlipressin, normal saline
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Acute Kidney Injury
Early Dry Cohort : Impact on the Fluid Balance of a Perfusion Based Protocol to Adjust UFnet During Deresuscitation in Intensive Care Unit.
Fluid overload is frequent and associated with mortality in critically ill patients, especially those with acute kidney injury. If fluid loading is a cornerstone of a resuscitation strategy, some authors promote an evacuation…
- Trial name
- Early Dry (NCT05119361)
- Testing
- Early Dry protocol
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury in the ICU
Automated System for Monitoring Urine Output in Intensive Care Patients
Acute kidney injury is common among ICU-admitted patients, and is associated with increased morbidity and mortality. Early recognition is essential to prevent complications.
- Trial name
- NCT05232045
- Testing
- Automated urinary output collection system group (tight monitoring of urine output)
- Where
- Israel
- Volunteers
- 1,800 people
- Sponsor
- Meir Medical Center
Biomarkers, Acute Kidney Injury
Vancomycin Exposure and Biomarker Tracking Using Real-time Monitoring of Interstitial Fluid
The goal of this observational study is to understand whether a wearable sensor (the Nutromics Sensor Device) can accurately measure drug and biomarker levels in the fluid just under the skin (interstitial fluid), instead of…
- Conditions
- Biomarkers, Acute Kidney Injury, Sepsis
- Trial name
- VENTURE (NCT07893223)
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Nutromics
Acute Kidney Injury
Arterial Stiffness and AKI Post-CABG
Acute Kidney Injury is a condition where your kidneys suddenly stop working properly and usually occurs if you are already unwell with an illness and can happen after having surgery.
- Trial name
- Heart-AKI (NCT02364427)
- Testing
- Arterial stiffness - Vicorder to measure pulse wave velocity
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- King's College Hospital NHS Trust
Sepsis, Acute Renal Failure
The Membrane Adsorbing OXiris Filter in Septic Patients With AKI
Patients with Sepsis / Septic Shock and AKI are submitted to Continuous Renal Replacement Therapy with the oXiris filter . The pro- inflammatory mediators , the endotoxin , interleukin 10 , the main cardiorespiratory indices and…
- Trial name
- MOSAKI (NCT03914586)
- Testing
- oXiris filter
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- FRANCO TURANI
Acute Kidney Failure
The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury
The primary objective is to safely determine if the investigators can identify the severity of Acute Kidney Injury (AKI) early in the course of the disease.
- Trial name
- NCT01275729
- Testing
- Furosemide
- Where
- 4 sites in United States
- Volunteers
- 96 people
- Sponsor
- University of Chicago
Hemodynamics Instability
Non-invasive Goal-directed thErapy oN cIrcUlatory Shock
Circulatory shock occurs when the oxygen supply to the tissues decreases, leading to cellular damage and affecting about one-third of patients admitted to Intensive Care Units (ICUs).
- Trial name
- GENIUS (NCT05336357)
- Testing
- Goal-Directed Therapy
- Where
- Brazil
- Volunteers
- 380 people
- Sponsor
- University of Sao Paulo
Acute Kidney Injury
Goal Direct Therapy to Prevent Acute Kidney Injury
This is an randomised controlled trial to investigate an strategy based in a protocol in prevention of acute kidney injury after cardiac surgery.
- Trial name
- GDT-AKI (NCT02396901)
- Testing
- Goal Direct Therapy
- Volunteers
- 214 people
- Sponsor
- University of Sao Paulo
Coronary Artery Disease
The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery
Cardiac surgery associated acute kidney injury (CSA-AKI) has been recognized as the second most common cause of hospital acquired AKI.
- Trial name
- NCT02496234
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Sapere Bio
Acute Kidney Injury
Rapid Evaluation of Acute Kidney Injury With NGAL in Acutely Ill Patients in the ICU
This is a multi-center, prospective, observational study of patients that are admitted to the intensive care unit (ICU). This study does not include any treatment or intervention and it is considered Nonsignificant Risk.
- Trial name
- REAL-ICU (NCT01294228)
- Where
- 28 sites in United States, Canada
- Volunteers
- 1,001 people
- Sponsor
- Abbott RDx Cardiometabolic
Acute Kidney Injury
Online Hemodiafiltration vs Conventional Hemodialysis in Acute Kidney Injury
Only limited data exist on the benefit of online hemodiafiltration in patient with Acute kidney injury. The objective of this pilot RCT is to assess the feasibility of a large multicentre RCT to determine whether, in patients…
- Trial name
- HDFAKI (NCT04525092)
- Testing
- Online Pre-dilution Hemodiafiltration, Conventional Hemodialysis, Online Post-dilution Hemodiafiltration
- Where
- 2 sites in Canada, Ireland
- Volunteers
- 45 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Kidney Injury
The Effect of Ulistin on Acute Renal Injury in Patients Undergoing OPCAB (Off Pump Coronary Artery Bypass): a Propensity Score Matched Study
Acute kidney injury (AKI) is a frequent complication after cardiac surgery. AKI has been reported as 7-40% depending on the type of surgery, and is known to increase to about 50% when there are risk factors.
- Trial name
- NCT04473144
- Testing
- Ulinastatin
- Volunteers
- 500 people
- Sponsor
- Ajou University School of Medicine
Diabetes Mellitus, Type 2, Coronary Artery Disease
POST-CABGDM: Empagliflozin in Perioperative CABG
Introduction: Diabetes Mellitus (DM) is a condition known to be associated with coronary artery disease (CAD) and its role as promoter of atherosclerosis is well stablished.
- Conditions
- Diabetes Mellitus, Type 2, Coronary Artery Disease, Coronary Artery Bypass Surgery, Acute Kidney Injury
- Trial name
- POST-CABGDM (NCT04523064)
- Testing
- Empagliflozin 25 MG
- Where
- Brazil
- Volunteers
- 155 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Kidney Injury, Renal Insufficiency
Novel Biomarkers for Risk Prediction of Contrast-Induced Acute Kidney Injury Post Coronary Angiography
Contrast-induced acute kidney injury (CI-AKI) has been recognized as the third most common cause of hospital acquired AKI, after hypotension-associated hypo-perfusion and post-operative AKI.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Kidney Diseases
- Trial name
- NORDICA (NCT02263820)
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Sapere Bio
Acute Kidney Injury
SGLT2 Inhibitors After Acute Kidney Injury With Indications Pilot
SGLT2i have been shown to reduce risk for mortality, progression of chronic kidney disease, and cardiovascular outcomes in these populations.
- Trial name
- NCT06124924
- Testing
- SGLT2 inhibitor
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Minnesota
Acute Kidney Injury, Obesity
Does the Presence of Preoperative Proteinuria Predict Postoperative Acute Kidney Injury in Obese Patients Undergoing Elective Laparoscopic Surgery?
Acute kidney injury (AKI) is a common, but significant complication after elective surgery which is associated with an increased risk of mortality, major adverse cardiac events, prolonged length of hospital stay, and increased…
- Conditions
- Acute Kidney Injury, Obesity, Proteinuria
- Trial name
- NCT02798042
- Testing
- Urine Sample
- Where
- United States
- Volunteers
- 1,434 people
- Sponsor
- NYU Langone Health
Acute Renal Failure
Influence Continuous Veno-venous Hemodialysis the Autoregulation
The aim of the study is to characterize the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.
- Trial name
- dARICUCVVH (NCT01376531)
- Testing
- continuous veno-venous hemodialysis
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Johannes Gutenberg University Mainz
Renal Insufficiency or Renal Failure &or End-stage Renal Disease
Cytokine Adsorption in Sepsis and Acute Kidney Injury
Aim of the study is to reduce the incidence of RIFLE stadium L and E after acute kidney injury in patients with severe sepsis/septic shock
- Trial name
- CASAKI (NCT02588794)
- Testing
- CytoSorb 300 ml device (3804606CE01)
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- Technical University of Munich
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