Clinical trials: Renal Injury, Acute
Kidney Failure, Acute, Contrast Media
Bicarbonate v Saline to Prevent Contrast Nephropathy
Slowing of kidney function occurs in a minority of people given dye during angiography. The purpose of this study is to compare two different types of fluid given into a vein to reduce the risk of kidney injury: salt in water or…
- Trial name
- NCT00384995
- Testing
- 0.9% (154 mEq/L) IV Sodium Chloride, 1/6 M (166 mEq/L) IV Sodium Bicarbonate
- Where
- 5 sites in Italy
- Volunteers
- 61 people
- Sponsor
- Italian Society of Nephrology
COVID, Severe Acute Respiratory Syndrome
LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)
To evaluate the proportion of subjects alive and free of respiratory failure (e.g. need for non-invasive or invasive mechanical ventilation, high flow oxygen, or ECMO) and free of the need for continued renal replacement therapy…
- Conditions
- COVID, Severe Acute Respiratory Syndrome, Sars-CoV2, Acute Kidney Injury
- Trial name
- NCT04402957
- Testing
- LSALT peptide
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 61 people
- Sponsor
- Arch Biopartners Inc.
COVID-19, Respiratory Failure
Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients.
At the beginning of 2020, a global alert emerged which saturated intensive care units due to COVID-19 worldwide. This caused a need for mechanical ventilation due to atypical pneumonias that had a rapid evolution and respiratory…
- Trial name
- NCT06208592
- Testing
- Sevoflurane with AnaConDa
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Hospital Español de Mexico
Emergency Surgery, Acute Kidney Injury
Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery
Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of blood…
- Conditions
- Emergency Surgery, Acute Kidney Injury, Hemoglobin
- Trial name
- NCT06857630
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Samsun University
Cardiac Surgical Procedures
Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .
To determine if ultrasound measurement of renal and carotid arterial resistive indices are associated with post-cardiac surgery acute kidney injury.
- Trial name
- NCT02580292
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
AKI (Acute Kidney Injury) Due to Trauma
Single-Center Prospective Study to Investigate the Difference in the Incidence of Contrast-Induced Nephropathy in High-Risk Patients With the Use of the Dye-Vert Plus System
Coronary angiography (CAG) for diagnostic or therapeutic purposes such as percutaneous coronary intervention (PCI) is one of the common procedures which require the use of intravenous contrast media.
- Trial name
- Dye-Vert Plus (NCT04279457)
- Testing
- DyeVert Plus System, Standardized hydration protocol
- Where
- United States
- Volunteers
- 1,802 people
- Sponsor
- CAMC Health System
Acute Kidney Injury, Cardiac Surgical Procedures
Terbinafine for CSA-AKI Prevention
Primary Objective: To evaluate the efficacy and safety of perioperative oral terbinafine in reducing the incidence of cardiac surgery-associated acute kidney injury (CSA-AKI).Secondary Objectives:To assess the effects of…
- Trial name
- NCT07738328
- Testing
- Terbinafine
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Guangdong Provincial People's Hospital
Aortic Surgery, Postoperative Acute Kidney Injury
Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach
Acute kidney injury after cardiac surgery has been reported to increase morbidity and mortality. Several risk scoring models for prediction of aortic kidney injury after cardiac surgery have been developed.
- Trial name
- NCT01844219
- Testing
- elective or emergency aortic surgery (including ascending, arch, descending thoracic aorta)
- Where
- South Korea
- Volunteers
- 375 people
- Sponsor
- Samsung Medical Center
Covid19, AKI
Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN-69 Oxiris) vs (Standard AN-69) in COVID-19
Abstract Title: Randomized,open-label, controlled trial to evaluate efficacy and safety of a highly selective semipermeable membrane (AN69-Oxiris) in comparison with a selective semipermeable membrane ( standard AN69) in COVID-19…
- Trial name
- oXAKI-COV (NCT04597034)
- Testing
- AN69-Oxiris, AN69-Standard
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Acute Kidney Injury
Mortality and Morbidity Associated With New Onset Acute Kidney Injury in Critically Ill COVID-19 Infection Patients
This study explored the incidence of morbidity and mortality associated with AKI in critically ill adult patients infected with COVID-19. There are two groups for comparison. Group1.
- Trial name
- NCT05964088
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Arrowhead Regional Medical Center
Critical Illness, Acute Kidney Injury
Continuous Renal Replacement Therapy Circuit Lifespan in Intensive Care Patients
The goal of this retrospective observational study is to evaluate how long continuous renal replacement therapy (CRRT) circuits remain in use in adult intensive care unit patients and to describe how CRRT pressure measurements…
- Trial name
- NCT07842562
- Testing
- Archived CRRT Device Log Data
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
AKI, CHD - Congenital Heart Disease
NO During CPB in Neonates to Reduce Risk of AKI
Acute kidney injury (AKI) following cardiac surgery for congenital heart defects (CHD) in children affects up to 60% of high risk-patients and is a major cause of both short- and long-term morbidity and mortality.
- Conditions
- AKI, CHD - Congenital Heart Disease, Surgery
- Trial name
- NCT04216927
- Testing
- Nitric Oxide, Oxygen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Kidney Injury, Multi Organ Failure
Long Term Renal Function After CRRT in the Paediatric Intensive Care Unit, a Follow-up Study.
In this study the investigators will evaluate the long-term renal function in children treated with continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) and multiple organ failure (MOF) in the pediatric…
- Conditions
- Acute Kidney Injury, Multi Organ Failure, Children, Only
- Trial name
- NCT05629273
- Where
- Sweden
- Volunteers
- 156 people
- Sponsor
- Region Stockholm
Acute Renal Failure, Kidney Disease
Prevention of Serious Adverse Events Following Angiography
The purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine (NAC) with oral placebo for the prevention of…
- Conditions
- Acute Renal Failure, Kidney Disease, Coronary Artery Disease
- Trial name
- PRESERVE (NCT01467466)
- Testing
- IV isotonic saline, IV isotonic bicarbonate, N-acetylcysteine
- Where
- 54 sites in United States, Australia and 2 more
- Volunteers
- 5,177 people
- Sponsor
- VA Office of Research and Development
Acute Kidney Injury
Effect of Vitamin E+Selenium on Kidney Function in Controlled Hypotension
The purpose of this study is to determine whether Kidney injury happens in controlled hypotension during brain operations by using Neutrophil Gelatinase Associated Lipocalin ELISA Kit and if so, does VitaminE+Selenium prevent it
- Trial name
- NCT01554345
- Testing
- vitamin E +Selenium
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Liver Cirrhosis, Acute Kidney Injury
Korean Cohort Study of AKI & HRS in Cirrhosis
The aim of this study is to investigate i) whether two biomarkers (urine NAG, urinary cystatin C) could be predictive factor in patient with liver cirrhosis, , and ii) whether these biomarkers can predict response of terlipressin.
- Conditions
- Liver Cirrhosis, Acute Kidney Injury, Hepatorenal Syndrome
- Trial name
- NCT03530761
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Soonchunhyang University Hospital
Acute Kidney Injury, Renal Insufficiency, Chronic
Intensified Acute Kidney Disease Care to Reduce Chronic Kidney Disease
Strategies to stop AKI-AKD-CKD continuum - Policy is one of the collaborative projects, Strategies to stop AKI-AKD-CKD continuum, Epidemiology, Immunology, Repair, Artificial intelligence, and Policy (EIRAP).
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Acute Kidney Disease, Decision Support Systems, Clinical
- Trial name
- ISACC (NCT04145609)
- Testing
- Multidisciplinary team (MDT) care and Acute kidney disease (AKD) clinic
- Volunteers
- 690 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Acute Kidney Injury, Kidney Failure, Acute
Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department
This retrospective observational study aims to evaluate the clinical characteristics and in-hospital outcomes of critically ill adult patients who underwent hemodialysis (HD) or continuous venovenous hemodiafiltration (CVVHDF) in…
- Conditions
- Acute Kidney Injury, Kidney Failure, Acute, Kidney Failure
- Trial name
- NCT07765030
- Testing
- Hemodialysis (HD), Continuous Venovenous Hemodiafiltration (CVVHDF)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Antalya Health Sciences University
Acute Kidney Injury, Continuous Renal Replacement Therapy
Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient
In patients requiring renal replacement therapy (RRT) in the intensive care unit (ICU), continuous techniques are predominantly using due to better hemodynamic tolerance.
- Conditions
- Acute Kidney Injury, Continuous Renal Replacement Therapy, Intensive Care Unit
- Trial name
- CompEER (NCT06369064)
- Testing
- CVVHD Dialysis parameters, CVVHDF Dialysis parameters
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cirrhosis, Liver, Hepatorenal Syndrome
HRS-AKI Treatment With TIPS in Patients With Cirrhosis
The study compares the effectiveness and safety of TIPS implantation in patients with HRS-AKI (stage1, 2 and 3) and liver cirrhosis with standard therapy (drug therapy with terlipressin + albumin).
- Conditions
- Cirrhosis, Liver, Hepatorenal Syndrome, Acute Kidney Injury, Ascites Hepatic
- Trial name
- Liver-HERO (NCT05346393)
- Testing
- TIPS, Standard of Care
- Where
- 14 sites in Germany
- Volunteers
- 124 people
- Sponsor
- Jena University Hospital
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