Clinical trials: Renal Injury, Acute
Acute Kidney Injury
The Role of Biomarkers in the Early Detection of Acute Kidney Injury Induced by Liver Transplantation
Renal dysfunction is a major risk factor for poorer outcome after liver transplantation. Nevertheless, mechanisms of renal dysfunction in liver transplant recipients are not clearly understood.
- Trial name
- KILT (NCT01333319)
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Kidney Injury
Pharmacokinetics, Pharmacodynamics and Safety of Basis in Acute Kidney Injury Study
This study will determine the pharmacokinetics, pharmacodynamics and safety of escalating doses of Basis following twice daily oral administration in patients with acute kidney injury (AKI).
- Trial name
- BAKIS (NCT03176628)
- Testing
- Basis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Acute Kidney Injury
Establish and Apply the Evaluation System of Ultrasonic Integrated Technology for Prevention and Treatment of Acute Kidney Injury
Establish an integrated evaluation system of ultrasound technology for the prognosis of acute kidney injury, and in order to achieve non-invasive, reliable early diagnosis "gold standard".
- Trial name
- NCT02347930
- Testing
- kidney ultrasound
- Where
- China
- Volunteers
- 196 people
- Sponsor
- RenJi Hospital
Hydronephrosis, Ultrasound
Hand-carried Ultrasound to Assess Hydronephrosis
This study evaluates if trainees can accurately rule out dilation of the renal collecting system on ultrasound (hydronephrosis) using hand-carried ultrasound (HCU). Trainees will undergo a short ultrasound training program.
- Conditions
- Hydronephrosis, Ultrasound, Acute Kidney Injury
- Trial name
- NCT03774719
- Testing
- Hand-carried ultrasound
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Washington University School of Medicine
Contrast-induced Nephropathy, Acute Kidney Injury
The Use of Inorganic Nitrate for the Prevention of Contrast-induced Nephropathy
Contrast-induced nephropathy (CIN), an acute kidney injury resulting from the administration of intravascular iodinated contrast media, is an important cause of morbidity/mortality following coronary angiographic procedures in…
- Conditions
- Contrast-induced Nephropathy, Acute Kidney Injury, Acute Coronary Syndrome
- Trial name
- NITRATE-CIN (NCT03627130)
- Testing
- Potassium Nitrate, Potassium Chloride
- Where
- United Kingdom
- Volunteers
- 640 people
- Sponsor
- Barts & The London NHS Trust
Remimazolam, Propofol
Remimazolam on the Incidence of Postoperative Acute Kidney Injury
We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the…
- Conditions
- Remimazolam, Propofol, Acute Kidney Injury, Hemodynamic Stability
- Trial name
- NCT07674719
- Testing
- Remimazolam (Byfavo), propofol
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Acute Kidney Injury, Sepsis
Predictive Value of Doppler RSI for Prediction of AKI in Septic Patients in ICU
Acute kidney injury (AKI) Diagnosis is based on rising creatinine. Intrarenal vasoconstriction occurs earlier and measuring flow resistance in the renal circulation (Renal Resistive Index (RRI)) could become part of vital organ…
- Trial name
- NCT04426032
- Testing
- Renal Doppler Ultrasound
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Kidney Failure, Acute, Myopathy; Drugs
The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)
The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure.
- Conditions
- Kidney Failure, Acute, Myopathy; Drugs, Heart Arrhythmia, Succinylcholine Sensitivity
- Trial name
- NCT06707532
- Testing
- Propofol, Rocuronium
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Gastrointestinal Hemorrhage, Liver Cirrhosis
Optimal Clinical Predictors to AKI in Cirrhotic Patients Experienced Acute Gastrointestinal Hemorrhage
Acute kidney injury (AKI) is a common complication, occurring in approximately 20% of hospitalized cirrhotic patients and has a significant negative impact on patients' outcomes according to either the initial stage (at the time…
- Conditions
- Gastrointestinal Hemorrhage, Liver Cirrhosis, Acute Kidney Injury
- Trial name
- ABC(AKI-B) (NCT04184934)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Kidney Injury, Postoperative Complications
Evaluation of Postoperative Organ Injury, Risk Factors, and Short-Term Clinical Outcomes in Patients Admitted to Intensive Care After Noncardiac Surgery
This retrospective observational study examines whether troponin levels measured before surgery are associated with acute kidney injury during the first 48 hours after surgery in patients admitted to intensive care after…
- Trial name
- TROP-AKI (NCT07907887)
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people
- Sponsor
- Ankara Training and Research Hospital
Machine Learning, Acute Kidney Injury
Machine Learning Predict Acute Kidney Injury in Patients Following Cardiac Surgery
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication which may result in adverse impact on short- and long-term mortality.
- Trial name
- NCT04966598
- Where
- China
- Volunteers
- 2,108 people
- Sponsor
- Yunlong Fan
Postoperative Acute Kidney Injury, Postoperative Complications
Hypotension Prediction Index-guided Hemodynamic Optimization Trial to Reduce Postoperative Acute Kidney Injury (HYT).
MAIN AIM OF THE STUDY To establish whether hemodynamic management guided by the hypotension prediction index (HPI) guided by the administration of intravenous fluids and vasoactive drugs in patients undergoing elective major…
- Trial name
- HYT (NCT05569265)
- Testing
- Intraoperative hemodynamic management
- Where
- 26 sites in Spain
- Volunteers
- 958 people
- Sponsor
- Maria José Clara Colomina Soler
Left Cardiac Catheterization, Percutaneous Coronary Intervention
Dapagliflozin to Prevent the Incidence of Contrast Induced Nephropathy After Heart Catheterization and Percutaneous Coronary Intervention
Left heart catheterization and percutaneous coronary intervention (PCI) has become a useful tool in interventional cardiology, in which iodinated contrast media is used.
- Conditions
- Left Cardiac Catheterization, Percutaneous Coronary Intervention, Acute Kidney Injury, Sodium-glucose Co-transporter 2 Inhibitors
- Trial name
- NCT04806633
- Testing
- Dapagliflozin 5mg
- Where
- 2 sites in Greece
- Volunteers
- 1,722 people
- Sponsor
- G.Gennimatas General Hospital
Acute Kidney Injury
PREdiction of succeSSful weanING From Continuous Renal Replacement Theraphy: the Possible Role of Delta C-cistatin
The goal of this observational study is to know if, in patients with acute kidney injury, naive for renal injurie, admitted to different ICUs, the change in plasma concentration of c-cistatin, between initiation and…
- Trial name
- PRESSING (NCT06714214)
- Where
- 3 sites in Italy
- Volunteers
- 152 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Kidney Injury, Chronic Kidney Diseases
Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration
To date, little knowledge exists related to the use of hemodialysis (HD) in infants and has been limited to mainly single center studies.
- Conditions
- Acute Kidney Injury, Chronic Kidney Diseases, Renal Dialysis
- Trial name
- ICONIIC (NCT05161078)
- Testing
- CARPEDIEM
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Critical Illness
Bedside Renal Ultrasound Assessment in Patients With Acute Kidney Injury
Exploring the predictive and evaluative value of various indicators of bedside critical renal ultrasound in critically ill patients with acute kidney injury (AKI)
- Trial name
- NCT06156098
- Testing
- No Intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qin Zhang
General Surgery
The GUARDIAN Pilot Trial
The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward MAP ≥80 mmHg (tight pressure management)…
- Trial name
- GUARDIAN (NCT04789733)
- Testing
- Tight pressure management, Routine pressure management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Cardiac Surgery
Neutrophil Gelatinase-associated Lipocalin as a New Biomarker to Detect Acute Kidney Injury in Postoperative Cardiac Surgery
Observational study aimed to test the ability of Neutrophil Gelatinase-associated Lipocalin (NGAL) concentration in blood and urine to predict and diagnose early acute renal failure (ARF) in patients after cardiac surgery…
- Trial name
- NCT01594788
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Severe Malaria, Malaria,Falciparum
Effect of Paracetamol on Kidney Function in Severe Malaria
A randomised open labeled, parallel-group, controlled trial to assess the efficacy of paracetamol to reduce kidney dysfunction caused by cell-free haemoglobin-mediated oxidative damage in paediatric patients with falciparum…
- Conditions
- Severe Malaria, Malaria,Falciparum, Acute Kidney Injury, Paracetamol
- Trial name
- PROTECtS (NCT04251351)
- Testing
- Paracetamol, Mechanical antipyresis
- Where
- Democratic Republic of the Congo
- Volunteers
- 460 people
- Sponsor
- University of British Columbia
Acute Kidney Failure
The Acetylcysteine for Contrast-Induced Nephropathy Trial
The purpose of this study is to evaluate the efficacy of acetylcysteine compared to placebo for the contrast-induced nephropathy prevention, between 48 and 96 hours after procedures that use contrast.
- Trial name
- ACT (NCT00736866)
- Testing
- Acetylcysteine
- Where
- Brazil
- Volunteers
- 2,300 people
- Sponsor
- Hospital do Coracao
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.